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J
TRT has been underwhelming for 4+ years - Low SHBG

But to answer your question a lot of the time I go by "feel" and do adjust "on the fly," which unfortunately is a recipe for disaster.
- JQ88
- Post #49
- Sep 24, 2015
- Forum: When TRT Is Not Enough (ED, Libido, & More)
J
TRT has been underwhelming for 4+ years - Low SHBG

60/250/.25 (2x/wk) at the same time had my T at 550 and e2 at 17 right before scheduled injection. All other numbers looked good. Tsh borderline high, I have added seaweed into my diet. However, e2 spike from HCG is unaccounted for. And Anastrozole doesn't block e2 effects from HCG anyways...
- JQ88
- Post #48
- Sep 24, 2015
- Forum: When TRT Is Not Enough (ED, Libido, & More)
J
TRT has been underwhelming for 4+ years - Low SHBG

Thanks Vince, Wow. No AI. I'm envious. I too have tanked my e2. I've been on the low side way more than the high side. My e2 seems to fluctuate, especially with HCG and I can't get labs every day. It was through this forum I've learned low e2 actually means higher body fat. So while I...
- JQ88
- Post #46
- Sep 24, 2015
- Forum: When TRT Is Not Enough (ED, Libido, & More)
J
HCG dose and timing for this TRT protocol?

Hi Nelson, I've been struggling to nail down a protocol for years. I really admire your literature and advice I have read through the years. I am so I decisive about HCG. I seem to get major e2 spikes from HCG, although I definitely feel it's mood uplifting benefits. I see you take...
- JQ88
- Post #7
- Sep 24, 2015
- Forum: Testosterone Side Effect Management
J
TRT has been underwhelming for 4+ years - Low SHBG

I have struggled to find a protocol that is consistent for almost two years now. That's why I asked about what works for you? I continue to be indicisive about HCG. Just not sure that it's necessary. So I go back and forth. I get bad e2 spikes from HCG, and Adex dosing becomes like hitting a...
- JQ88
- Post #43
- Sep 24, 2015
- Forum: When TRT Is Not Enough (ED, Libido, & More)
J
TRT has been underwhelming for 4+ years - Low SHBG

Vince Carter, I'd love to hear your current protocol. E2 should be quite similar to shbg for optimal sexual functioning. So if your SHBG is 14, then you will have to lower your e2 to around 14. You will become a stud in the bedroom, however you might experience some low e2 symptoms. Also...
- JQ88
- Post #41
- Sep 24, 2015
- Forum: When TRT Is Not Enough (ED, Libido, & More)

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038