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  1. R

    Almost one year on TRT... struggling to find balance

    Forgot to mention: I'm highly suspicious of HCG as a cause of the anxiety/rapid heart rate feeling I've had during my time on TRT. When I first started, they had me injecting HCG the day BEFORE Test and I would always notice especially high anxiety/rapid heart rate that day. Also, when they...
  2. R

    Almost one year on TRT... struggling to find balance

    So I've posted a few times around here. Started TRT last September, so right around 10 months as of now. It has been a journey, for sure. If I'm being honest, I've felt "ok" or "bad" more than I've felt good, but it's been better than pre TRT overall, so that's worth something. I'm with...
  3. R

    Decoding SHBG and primary vs. secondary

    You're probably right. Overall, I think it has been a good choice to go the TRT route, if I could only figure out the estrogen issue. I'm 31, fit (12% or so bodyfat gaged by visible abs/muscle definition), yet my E2 has continually been the problem for the 9 months I've been on TRT. I get to a...
  4. R

    Decoding SHBG and primary vs. secondary

    Vince, You're probably right. Overall, I think it has been a good choice to go the TRT route, if I could only figure out the estrogen issue. I'm 31, fit (12% or so bodyfat gaged by visible abs/muscle definition), yet my E2 has continually been the problem for the 9 months I've been on TRT. I...
  5. R

    Decoding SHBG and primary vs. secondary

    You make a good point, thanks for your feedback.
  6. R

    Young Men Had Low Testosterone Symptoms with T Under 400 ng/dL

    I am 31 and was at 333 prior to TRT and felt AWFUL. Like, could barely make it through the day or stay awake in the mid-afternoon/evening, zero libido, zero energy. So add me to to the list of this being very true.
  7. R

    Decoding SHBG and primary vs. secondary

    I've been on TRT for nearly 9 months now. My initial labs, before starting, were as follows: Initial labs (pre-trt): Total T: 3.33 (2.8-8.0) Free T: 6.1 (8.7-25.1) SHBG:69 (16.5-55.9) LH: 5.6 (1.7-8.6) Estradiol sensitive: 19.6 (8-35) Most recent labs (taken the morning before injection on an...
  8. R

    AI + HCG timing on EOD protocol

    Thanks for advice Vince. So let's say I keep current EOD protocol (it's a true EOD, not M/W/F), and want to try just adding hcg without an AI for 4-6 weeks and testing to see where e2 goes... when should I inject hcg? I'm looking to start with 500 IUs per week and see if that gets balls back...
  9. R

    AI + HCG timing on EOD protocol

    I've been on TRT for 7-8 months. Started with Test + HCG + AI two times per week. After some research, hoped that switching to EOD would eliminate need for AI, but unfortunately, it's still creeping up. After 7 weeks on EOD Test only, E2 is 42 and I'm feeling it with water retention, hot...
  10. R

    What is the best dose of HCG? Dr Saya presents two case studies.

    Dr. Saya, I'm a Defy patient as well -- 6 months. Starting out, I was on 80mg Test Cyp, 250IU's HCG, and .25 anastrozole (all twice per week). After three months, my labs came back with Total T above 1500, Free T 42, and E2 at 49 --- and I was feeling it. Fatigue had returned, lots of...
  11. R

    Lab Results and Your Input

    Thanks Gotcha, thanks for your feedback.
  12. R

    Lab Results and Your Input

    SHBG is 69.
  13. R

    Lab Results and Your Input

    Hey all, First time poster here. I've suspected low T for a few years, but after finally convicing my Doc to test for it 3 years ago, he would only look at Total T and it came back at 6.6 (2.80 - 8.00), so he said "you're just stressed" and sent me on my way. I've been in his office once per...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic

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