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K
Nice review of the time-course of the effects of TRT

You raise some valid concerns that I would agree with.
- KSPhD
- Post #3
- Apr 19, 2017
- Forum: Testosterone and Men's Health Articles
K
Nice review of the time-course of the effects of TRT

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188848/
- KSPhD
- Thread
- Apr 19, 2017
- Replies: 3
- Forum: Testosterone and Men's Health Articles
K
New to Defy: Protocol and Supplies - Questions

JohnDoe - I'm in the 300 Total /20 E2 range...
- KSPhD
- Post #8
- Apr 17, 2017
- Forum: Testosterone Basics & Questions
K
New to Defy: Protocol and Supplies - Questions

Thanks Vince, I was curious too. I used clomid previously and that elevated my estrogen quite a bit.
- KSPhD
- Post #5
- Apr 17, 2017
- Forum: Testosterone Basics & Questions
K
New to Defy: Protocol and Supplies - Questions

Thanks Vince!
- KSPhD
- Post #3
- Apr 17, 2017
- Forum: Testosterone Basics & Questions
K
New to Defy: Protocol and Supplies - Questions

Had a phone consult with one of the docs at Defy today. I will speak with someone tomorrow about getting the prescriptions, needles and so forth. I was wondering what you would recommend in terms of needle size, syringe size, and other supplies. Also what is the most affordable way to get the...
- KSPhD
- Thread
- Apr 17, 2017
- Replies: 26
- Forum: Testosterone Basics & Questions
K
Does Testosterone Replacement Affect the Thyroid?

The only study I have seen was with supraphysiological doses of T, and even then the changes in Thyroid function were small.
- KSPhD
- Post #20
- Apr 15, 2017
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
K
Constipation - Is it TRT - Metformin

Test cyp seems like the most unlikely cause. Metformin and AI's are known to cause constipation. Take a fiber supplement morning and night, drink lots of water. Do you need the metformin for diabetes or is this being Rx'd for aging reasons?
- KSPhD
- Post #4
- Apr 15, 2017
- Forum: Health & Wellness
K
Testosterone (or Anastrozole?) Decreased my HDL: What Can I Do?

Full text for those who are interested. Nelson, there is a higher hazard ratio for those at the very bottom and those at the very top. But if you look at Table 2, there is a difference in incidence rates for men (comparing <30 and >51) of ~7 / 1000 person years. I don't think this is much to...
- KSPhD
- Post #5
- Apr 13, 2017
- Forum: Testosterone Side Effect Management
K
Testosterone (or Anastrozole?) Decreased my HDL: What Can I Do?

I think the HDL woes are overblown. If you are over 40 mg/dl you are likely just fine. Most people can get there easily eating well and moving more or participating in structured exercise. HDL boosting drug trials have all failed over the past decade as they don't impact mortality. The newest...
- KSPhD
- Post #3
- Apr 13, 2017
- Forum: Testosterone Side Effect Management
K
Dr. James Carroll - Houston Texas

You also have Larry Lipshultz Houston.
- KSPhD
- Post #4
- Apr 13, 2017
- Forum: Doctor and Clinic Reviews
K
Nostril breathing increases nitric oxide

This sounded like hokum, but there appears to be some support for this in the scientific literature. http://onlinelibrary.wiley.com/doi/10.1002/ar.20782/full
- KSPhD
- Post #4
- Apr 1, 2017
- Forum: Health & Wellness
K
Need fish oil recommendation

Worth a look. https://labdoor.com/rankings/fish-oil http://www.nutrasource.ca/ifos/product-reports/default.aspx
- KSPhD
- Post #35
- Mar 25, 2017
- Forum: Nutrition and Supplements
K
TUDCA: Elevated Liver Enzymes or Triglycerides...

Anyone have experience supplementing with TUDCA (Tauroursodeoxycholic Acid) to lower triglycerides or liver enzymes? Was it effective?
- KSPhD
- Thread
- Mar 21, 2017
- Replies: 2
- Forum: Nutrition and Supplements
K
Creatine: Everything You Need To Know

Vince, that is likely a function of age. The GFR declines after age 45 at ~1 ml/min.
- KSPhD
- Post #8
- Mar 19, 2017
- Forum: Nutrition and Supplements
K
Creatine: Everything You Need To Know

Nice summary Will. One of the more exciting benefits extending beyond human performance is the potential protective effect in fatty liver disease. A recent review is attached for those interested...
- KSPhD
- Post #2
- Mar 18, 2017
- Forum: Nutrition and Supplements
K
TRT in Kansas City?

Thank you Vince. I appreciate the info. How has your experience been with Defy? Are the costs reasonable?
- KSPhD
- Post #4
- Mar 9, 2017
- Forum: Doctor and Clinic Reviews
K
TRT in Kansas City?

Has anyone been able to locate a good doctor in the Kansas City area? I have hypogonadism, and have used clomid until now for fertility reasons. I am off clomid, but most local physicians are pushing creams or pellets - neither of which interest me. Thanks!
- KSPhD
- Thread
- Mar 8, 2017
- Replies: 25
- Forum: Doctor and Clinic Reviews

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038