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  1. H

    Permanent crash of estrogen?

    A lot of high cortisol symptoms are the same as low e2 symptoms so you gotta keep that in mind, you seem really stressed and anxious at the moment so that’s most likely what it is and especially if you say dhea helped you as many times when dhea is low cortisol is high.
  2. H

    Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!

    That’s actually really interesting, I’ll have to read more into it and try it myself. I like to go the more natural route myself when i can when it comes down to mental health.
  3. H

    Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!

    I’ve been reading a lot into the NEM stress response and when your body is in a constant state of fight or flight/stress such as with most people nowadays, it gets overwhelmed and switches to your primal system to survive(limbic system) same case for depersonalization. When this happens your...
  4. H

    Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!

    24mg a day and I still have frequent urination but only cause I’m on natural diuretics for high blood pressure
  5. H

    Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!

    Feeling like my old self again and even better actually now that I have much less stress in my life, am more driven, and have worked through my issues (GAD, OCD, depression, etc) the testosterone only further amplifies that ambition and drive and positive traits whereas before I feel like it was...
  6. H

    Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!

    That would also explain why some members low e2 symptoms got worse as they raised the dose of testosterone after crashing because it just increased the issue of overstimulating the nervous system more causing more anxiety which then becomes a vicious cycle
  7. H

    Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!

    yup, weight gain only around midsection hard to put on muscle/lack of muscle glycogen constant joint pain. Crippling Fatigue after eating where I wanted to fall sleep and a whole plethora of weird symptoms for years and years with weird reactions to certain foods/supplements that are supposed...
  8. H

    Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!

    I think I might’ve figured it out guys or at least in my case. It took me coming off testosterone going through anything and everything to reduce my stress in life/fix my ocd and reduce my anxiety and I believe the issue comes down to hpa axis dysfunction/overstimulation, depersonalization...
  9. H

    Estrogen valerate injections for crashed e2 symptoms

    Same problem here after years of using aromatase inhibitors, only gotten worse on trt so trying to come off with hcg and and a serm as my body only seems to respond to those instead of exogenous hormones. Serms make my low e2 symptoms worse but just gonna bear through it as I have nothing to...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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