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Why Clomid Fails: The Zuclomiphene Threshold
Since both Clomid isomers are excreted primarily (50%) via the gut Cal-D-Glucarate shouldn't have much affect since it works at the renal(kidney) level to increase glucuronidation of different chemicals/hormones. A mere 8% of clomid excretion appears to take place in the kidneys. It certainly...- socks
- Post #10
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T
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Why Clomid Fails: The Zuclomiphene Threshold
I linked to my sources, might have missed one. I'd been writing this up in Word and its now to the point I thought it would be useful to share.- socks
- Post #3
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T
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Why Clomid Fails: The Zuclomiphene Threshold
Part One: Clomid Introduction - Selective estrogen receptor modulator, which occupies e2 receptors acting as a weak estrogen - Two parts/isomers, 30-50% zuclomiphene(estrogenic) and 50-70% enclomiphene (non-estrogenic) (1) - Inhibits negative feedback of e2 primarily at the...- socks
- Thread
- Replies: 22
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T
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Need Advice! 23 Year old male
Interesting, how'd they reach that conclusion? I've assumed from my reading that Docs usually rely on actual response to dosing(clomid/hcg challenge stuff) to genuinely determine primary vs secondary.- socks
- Post #10
- Forum: Testosterone Basics & Questions
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What do you do for maintaining size?
Cut the cardio to minimal amounts and focus on using/building metabolically active tissue (muscle) if you want to get leaner. If not able to physically lift weights (injuries), be sure to rely primarily on cardio that utilizes a lot of muscle, ie. stairmill/stepper or inclined treadmill instead...- socks
- Post #4
- Forum: Workouts & Routines
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Need Advice! 23 Year old male
Hey partner, you should definitely reach out to a TRT service provider like defy or primebody who can link you up with a Doc in your area that's competent. If you total T was higher, I'd say you look secondary, but as your numbers exist, you could certainly have some dysfunction at the...- socks
- Post #8
- Forum: Testosterone Basics & Questions
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Three Weeks on Clomid - Lab Results
What's your dosage protocol? This is the first time having your low T addressed? You have great Free T, but I've heard it's around the Total T level of 650-700 that things actually start to feel better assuming free t stays in midrange. Looking forward to hearing more as I'm in a similar...- socks
- Post #6
- Forum: Blood Test Discussion
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Testosterone half life table
Here's a little more detailed analysis for those of you interested.- socks
- Post #12
- Forum: Testosterone Basics & Questions
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Is Clomid working?
Not sure if it was a typo, but "calcium gluconate" is not indicated in estrogen management. It's calcium-d-glucarate that Saya and many others typically recommend. On e2, I've heard another Doc mention a 10:1 ration as the minimum they shoot for between free t:e2. So right now you're toeing...- socks
- Post #15
- Forum: Testosterone Basics & Questions
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Is Clomid working?
On SHBG levels, indeed liver issues or diet can play a role there. One study on men found an inverse relationship between Vitamin D levels and SHBG. Have you Vit. D checked on next panel. On increased appetite, could be related to Clomiphene's effect on various brain regions that regulate...- socks
- Post #13
- Forum: Testosterone Basics & Questions
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