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    Severe Sides After Ceasing 25mg Clomid + 1mg Anastrozole

    Thank you so much for the support, seriously. Easily the worst ~6 weeks of my life. I've had food poisoning multiple times, dislocations, "stress" with finances and relationships, but I have never before felt like I was literally losing my mind and personality at the same time. I'm so glad to...
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    Severe Sides After Ceasing 25mg Clomid + 1mg Anastrozole

    Thanks. I'm going to get a fresh lab with no biotin interference to conclusively figure out my Free T/E2 ratio. With that I'll be able to either do something about crashed E2 or rule it out.
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    Severe Sides After Ceasing 25mg Clomid + 1mg Anastrozole

    It's been 5 weeks and you've said I'm only past one half-life; what is the generally understood half-life of the zuclomiphene isomer?
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    Severe Sides After Ceasing 25mg Clomid + 1mg Anastrozole

    Appreciate that reply. I searched the forum further and it looks like 6-8 weeks is a reasonable time for things to settle naturally. I'm only at 5 weeks and have been improving so I'm going to wait it out.
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    Severe Sides After Ceasing 25mg Clomid + 1mg Anastrozole

    Yeah, after bixt's reply to my post I researched further. I think crashed E2 hasn't been showing up on labs due to my multivitamin having 1,367% of the daily recommendation of Biotin. Would crashed E2 present as low estrodial on the sensitive test or is there a separate test for E2? I'm...
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    Severe Sides After Ceasing 25mg Clomid + 1mg Anastrozole

    So, I actually agree with this while I was still taking both. But do you think the fact that I'm still having wild anxiety episodes 5 weeks later could be attributed to the anastrozole despite the much shorter half life than zuclomiphine? Honest question, I'm new to this...
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    Severe Sides After Ceasing 25mg Clomid + 1mg Anastrozole

    I'd just like to strongly warn anyone against taking regular Clomid for HRT purposes. I'm almost 5 weeks out since my last dose and am still nowhere near myself. My life has basically been put on hold for over a month as I have no way to know when I'm going to be "triggered" and freak out about...
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    Severe Sides After Ceasing 25mg Clomid + 1mg Anastrozole

    From what I've read, there are a few things this doc did wrong: 1. Prescribed Clomid instead of Enclomiphine 2. Started at 25mg ED out of the gate; seems like 12.5mg is a better place to start, and possibly not even every day. 3. Two 1mg doses of Anastrozole per week is extremely high. He also...
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    Severe Sides After Ceasing 25mg Clomid + 1mg Anastrozole

    Firstly, wanted to say thank you to everyone here as I've gotten a lot out of searching this forum while dealing with all of this, and also found Defy Medical here who has been very helpful. Back in August 2021 I had a lab done showing Total T at 346 with Free T at 43.7 pg/mL. My primary doc...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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