Sounds good. There is no real trough with a 2x daily application. If you Look at the pharmacokinetics there’s about a 23% decrement 12 hours after application. Creams are not treated like injections with regard to through measurements. Levels differ in every man but for the most part 100 mg...
He measures 5 hours after application. 1600. Free 53. Feel better than ever and ever thing we can measure had improved. So when it is all said it’s what makes me healthier not what makes you happy or your opinion based on not treating 1 single patient
Symptoms first and foremost along with free T It’s that simple. Of course he is optimizing all the other hormones as well. But like I said he is not caught up in the number. If your free is 35 ng/dl for instance and you are still symptomatic he will give you the option of raising the dose to...
Dr Nichols typically starts men on 2 clicks (100mg) twice per day and adjust dosage based on symptoms and levels (free T). He has a few on 4 clicks 2x per day but anything more than that is cost prohibitive and instructs patients they would be better off doing injections. Nichols is the one that...
Jay Campbell is still a close friend and big fan of Dr Nichols. He mentions him on just about every podcast he does on testosterone including the most recent with Dr Anthony Jay (who is also a big supporter of Dr Nichols) concerning gynecomastia.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
⚠️ Medical Disclaimer
This tool provides predictions based on statistical models and should NOT replace professional medical advice.
Always consult with your healthcare provider before making any changes to your TRT protocol.
ℹ️ Input Parameters
Normal range: 300-1000 ng/dL
Predicted Hormone Levels
Enter your total testosterone value to see predictions
Results will appear here after calculation
Understanding Your Hormones
Estradiol (E2)
A form of estrogen produced from testosterone. Important for bone health, mood, and libido.
Too high can cause side effects; too low can affect well-being.
DHT
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth,
prostate health, and masculinization effects.
Free Testosterone
The biologically active form of testosterone not bound to proteins.
Directly available for cellular uptake and biological effects.
Scientific Reference
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
