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  1. G

    Damage to my penis... please help

    You might also try DMSO which seems to benefit just about everything.
  2. G

    Damage to my penis... please help

    This is just a wild guess on my part, but a vacuum penis pump might be worth a try. The concept would be that it draws blood into the penis and the increased blood flow might be therapeutic. There was also a study posted here a while back that said Hyperbaric Oxygen Therapy increased vascular...
  3. G

    Help with blood test results and erectile dysfunction

    Several things: - Time Restricted Eating is essential no matter what. Specifically, start by eating within an 8 hour time window so that your are only drinking water for 16 hours per day. Part of insulin resistance appears to be that cells are over-stimulated by constant exposure to insulin, so...
  4. G

    Male...gaining slight fat with cellulite in thighs all of a sudden even with normal lab results

    You are making a claim that does not seem to be supported by evidence or logic, so you you need to cite some or expect your position to be challenged. For example, aromatizing compounds are well-known to lead to gyno in some people and be countered by an AI. Gyno is at least partially fat...
  5. G

    Starting TRT Soon

    I can't remember if I mentioned this before but have you tried timed-release melatonin for sleep? It sounds like some sort of dopamine or cortisol issue but melatonin might help. A spoonful of quality honey before be d might also help if it a low blood sugar issue. Also, I've run across several...
  6. G

    Male...gaining slight fat with cellulite in thighs all of a sudden even with normal lab results

    Stress can certainly impact cortisol, so it sounds like that is a prime candidate for your issues. When dealing with any difficult issue however, you want have everything working in your favor, and you want most stored fat in your body to be saturated fat, not PUFAs. Resolution of cellulite is...
  7. G

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    I've never used this product but I do use 100% DMSO all the time and it can certainly be a little harsh on the skin in some places. Mixing whatever your normal dose of alphagels with the 70%DMSO/30% aloe-vera blend might reduce the skin issues.
  8. G

    Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis

    Thanks for posting this. This implies that blood pressure should rise if blood viscosity is in fact rising in a problematic way, however I've had a mysterious rise in HCT with no rise in BP that I can tell. I'm wondering (hoping) that perhaps BP can be used as a way to tell if a rise in HCT is a...
  9. G

    Male...gaining slight fat with cellulite in thighs all of a sudden even with normal lab results

    Have you eliminated all seed oils from your diet? Do you have any reason to think your cortisol may have increased? High cortisol can cause abnormal fat deposits (see Cushings Syndrome/Disease).
  10. G

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    Personally, if they're the only source, I wouldn't let this scare me away. There's nothing wrong with DMSO and if the DHT works then it works. MT-2 was known to be under-dosed from the non-US/CA sources but it is so strong and you have to dose by experimentation anyway so it doesn't really matter.
  11. G

    Testosterone Therapy Induced High Hematocrit- Can Therapeutic Phlebotomy Be a Double-Edged Sword?

    "Testosterone stimulates the production of red blood cells (erythropoiesis) by initially increasing erythropoietin (EPO), establishing a new EPO/hemoglobin "set point," This seems underappreciated and could explain why some of us have our HCT jump up and stay up for no apparent reason. On the...
  12. G

    Looking for honest advice on hematocrit

    Is it possible you were under-hydrated for the test where your HCT was higher? That could do it.
  13. G

    Blood test feedback (incl before, during, after KETO - impressive results)

    The issue with sleep and keto (i had the same issue) as I understand it is low blood sugar episodes provoking cortisol release at night which puts the body into an awakened state. You can having your carbs late evening, or having a large serving of glycine late evening. I went away from strict...
  14. G

    Help with blood test results and erectile dysfunction

    I agree with the direction Funk is suggesting which is to look for root cause issues. If viagra is not working that suggests a lack of Nitric Oxide production, so things like Beet Root powder, Nitric Oxide tablets, sunshine and HIIT would be good to try. Bi-mix or Tri-mix would be another option...
  15. G

    Warning for Men on TRT: Low Ferritin is Bad

    Many thanks for taking the time to put that together. My original concern was avoiding iron overload, however in the last year my hematocrit jumped up for no known reason so I am now donating blood a bit more frequently to keep it i check, but I have no symptoms of low iron. I have quercetin on...
  16. G

    Dosages

    Hmmm. A brief experiment with a form of T that leaves your system quickly might be fine as an experiment, however that sounds like some sort of infection or nutrient issue. Have you been to a holistic doc who specializes in fatigue? Lyme disease is very tricky to diagnose but could cause that...
  17. G

    Warning for Men on TRT: Low Ferritin is Bad

    Two questions: 1) since the amount of iron that can be carried by Ferritin can apparently vary massively, how can ferritin alone be a good measure of available iron? My understanding is that TIBC is a better measure but I would be interested in your thoughts, and 2) if someone is trying to...
  18. G

    Dosages

    As other threads have discussed, the dosage to reach a particular blood level can vary from person to person, so there is a degree of experimentation involved. I agree with Vince that starting low and adjusting up after a couple of months if your symptoms dictate is a good approach. What...
  19. G

    What is the Salt Trick for Men ? : Salt, Healthy Blood Pressure Levels, and Libido.

    More good info in the link below, especially regarding the affect of salt on Zeta Potential and the factors involved in finding healthy salt. https://www.midwesterndoctor.com/p/the-truth-about-salt-efa
  20. G

    Melanotan 2 Question

    I recommend starting with 100-300 mcg (micrograms) and then adjusting upward if necessary. The people who seem to have bad reactions start with higher amounts. For me, it is not a night and day miraculous difference, but a very noticeable bump in the right direction, which I combine with dozens...
  21. G

    Melanotan 2 Question

    No. It requires sun exposure.
  22. G

    Does arthritic elbow mean I can't lift weights?

    For me, the key to the descent is to envision the muscles tensioning like a spring or rubber band, so my cue on the descent is to think “coil, coil,coil…”. This is what powerlifters mean when they say “stay tight”. I only inhale and then hold my breath if necessary until the lift, at which point...
  23. G

    Does arthritic elbow mean I can't lift weights?

    First of all, kudos to you for being open-minded enough to try new things. Most people use an issue as an excuse to stop lifting. Several comments… Something I’ve noticed is that when you injure a joint, the body seems to try to protect itself by immobilizing the joint by locking up the muscles...
  24. G

    Immunodeficient / Looking for Guidance Starting Peptides & Other Injectables

    Regarding Vitamin C, you can take higher levels while your body is fighting an infection (think of C as being like the bullets for your innate immune system "gun") however I back down as soon as I start to feel better. It will provoke diarrhea if you take too much but I've never had an issue. I...
  25. G

    Melanotan 2 Question

    For me it's the same. The tanning is excessive however.
  26. G

    Immunodeficient / Looking for Guidance Starting Peptides & Other Injectables

    A few ideas. Regarding recovery from illness, I would start with micro-nutrients. Do you ramp up you vitamin C intake whenever you feel an illness coming on? By ramp-up I mean go from maybe a gram per day to 5-10 grams per day? And add-in liposomal C? In addition, Vitamin D blood levels over 50...
  27. G

    0.25mg oral Finasteride daily - risk of Post-Finasteride Syndrome?

    I have recently started using red light therapy for joint issues and in reading about it, it seems to have a pro-hair affect as well. I use the $90 face mask sold on amazon but it is a flexible mat that you can form to use almost anywhere including the top of your head. Also, there have been a...
  28. G

    Does arthritic elbow mean I can't lift weights?

    I've had tons of joint issues, they come with lifting and living, but thankfully they've all pretty much resolved and I'm lifting as much as ever for the most part. Look through the tread "Fixes for Joint Issues." A few highlights and things I need to go back and add to the other thread: - DMSO...
  29. G

    Latest developments in Parkinson's disease biomarkers

    Vitamin D is apparently helpful for PD, as with so many other things https://articles.mercola.com/sites/articles/archive/2025/05/26/vitamin-d-and-parkinsons-disease.aspx Also, I heard an interview with Dr. Bredesen where he said his dementia reversal protocol was showing benefit for...
  30. G

    About to Start a New Protocol

    This is an essential point and one that doesn't get nearly enough emphasis. I'm so used to doing this that I completely missed it but thanks to Phil for bringing it up
  31. G

    About to Start a New Protocol

    Your plan and reasoning seems sound. An observation however...It sounds like you need to develop the ability to act independently from your Doctor, both for practical reasons (most of us have had to make dozens of tweaks to get to where we are in a good spot which would have been frustrating and...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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