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  1. G

    Benefits Add Up for Regular Aspirin Use

    When I looked into this, the affect of aspirin lasts for several days at least, so intermittent dosing makes sense. Also, from what I can tell, the bleeding risk is way overblown. People have been taking 81 per day for decades with no apparent issues. I take 325mg immediate release 2-3 times per...
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    American men are hungry for injectable T: A legion of new health clinics are serving it up

    Something I've observed that may be driving some of the "more is better" mentality is that many people (mostly men) do their gym protocols in a manner that essentially comes down to "try harder", which is what the 1-2 sets to failure approach boils down to. This will work to some degree for the...
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    Oxandrolone (Anavar) Medical Uses- Presentation Attached

    So are you saying Oxandrolone suppresses estradiol (which I've never heard anyone else report) or that it suppressed your Testosterone and that in turn suppressed estradiol?
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    Lithium

    The anti-aging author and doctor, Dr. Sandra Kaufmann is a huge proponent of lithium. She covers it in one of her books I think and has spoken about it on several podcasts.
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    Blood panel, how's mine look?

    If one has both HCG and Kisspeptin on hand, is there a case for alternating them by injecting each once per week? Are they potentially doing similar but slightly different and complimentary/synergistic things?
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    Any Testosterone Propionate Compounding Pharmacies left?

    An observation...There have been several posters here over the years (the most recent one was about a year ago I think) who reported excellent results injecting at very long intervals, every three weeks in one case I remember. Of course there were people here who said that couldn't be true, but...
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    HCG induced aromatase down regulation?

    I've had what could be a similar situation although I can't directly tie it to the HCG. I can definitely say that HCG does not necessarily rise E2. Mine was rock bottom for a while on test and HCG. I thought maybe something else was blocking aromatase like melatonin or Cialis, but maybe your...
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    Is it time for TRT?

    Since you're trying for a child, I would say that it is essential to try Clomid/Enclomiphene or HCG first. Also note that your symptoms (including low T) could be due to things other than hormones, particularly some sort of chronic infection such as lyme disease. You could also have some sort of...
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    Taurine – What's It Good For?

    ergo-log and examine.com are two places to start https://ergo-log.com/taurine-archives.html
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    Advice on where to find trustworthy peptides

    Several things: - I agree with Nelson on Peptide Sciences. I've used them for years. I have also used nootropic source. - I have also used Phase4 (max-supplement.com) for transdermal patches for BPC. They have sketchy overtones, but I have had great results. I have no issue with injections in...
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    Blood panel, how's mine look?

    What are you referring to here? Also, have you checked E2 at your current lower dose? I too seem to feel better at lower doses but my E2 has been too low, at least on paper. I'm becoming more intrested in the E2 injections.
  12. G

    Oxandrolone Decreasing Abdominal Fat

    I mention it in the context of minimizing T suppression for those who are not on anything else, similar to the protocols that combine it with oral T. I agree that Oxandrolone alone is likely a better thing to try first before jumping into TRT if gym/body comp are the primary goals.
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    Oxandrolone Decreasing Abdominal Fat

    The net takeaway seems like more evidence that men looking to start TRT solely for gym/body composition reasons might want to consider enclomiphene/oxandrolone to start with, although at a lower dose and focused on the post-training anabolic window.
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    Indirect way of monitoring E2 without blood test?

    A best I can tell, higher E2 is better for me (higher being above rock bottom) but libido is really not an issue for me. Some people are high responders to DHT and similar substances but as far as I can tell I'm not. Creatine also supposedly raises DHT, but I suspect moderate rises are offset by...
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    Blood panel, how's mine look?

    Yes. It's just like when you put a muscle in a cast. It/They atrophy from lack of use
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    Feeling pretty sick following this mornings shots ...

    I agree with Phil. Also, in many years of observing the hormone space, AIs seem to be the single highest risk for causing major hard-to-resolve issues, so doing other things, like splitting dosages, adjusting dosages, changing ester/formulation, and using other things that have a mild AI affect...
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    Indirect way of monitoring E2 without blood test?

    Another option is to supplement things that act like and AI such as Zinc, melatonin and Cialis, but which don't seem to have the excessive and unpredictable downsides of AIs, and go by symptoms from there. I have the opposite problem of trying to raise E2 so I have been on the lookout to avoid...
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    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    If soreness is your primary issue, it’s possible that lack of anabolism is part of the problem, but it sounds like your protocol should be doable without much soreness. Jumping to Oxandrolone before ruling out some other fundamental issues seems a bit premature so before you jump to that I would...
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    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    I would try it and see. A lot will depend on your how recovery-friendly your lifting protocol is. I (almost) never do a set to failure, but I do a lot of near-maximal sets and I have found that this massively reduces the recovery time needed while also letting me do far more near-maximal volume...
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    About to Start a New Protocol

    I just went back and read your initial post, and unless I missed it somewhere else, I don't see where you've done a thorough check-up with a Holistic/Integrative Doc, someone who would check for nutrient status, long-term infections (e.g. lyme) and other things that could cause your symptoms...
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    The significance of selegiline/(-)-deprenyl after 50 years in research and therapy (1965-2015)

    I cut the pills in half. They are quite small but they could be cut again with a pill splitter but I am fine with the 2.5 mg dose, at least in theory since I don't feel anything similar to Gman.
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    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    Yes. It's not going to do as much as that plus other anabolics, however I think it's a viable approach if one want a moderate boost. Many people who start TRT looking primarily for gym gains should IMO start with some sort of minimally suppressive protocol such as enclomiphene/oxandrolone...
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    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    FWIW, I've found the same thing when I cut my dose of Test cyp, at least in the short term. I would do so permanently and add in Oxandrolone for the anabolic effects, except that my E2 is already very low and I haven't wanted to get into supplementing E2 directly.
  24. G

    Building a TRT protocol around hCG

    Have you run into any strategies for raising E2 in those of us who are perpetually low? I use HCG and my T is high normal but E2 is constantly very low.
  25. G

    Help with blood test results and erectile dysfunction

    I agree with Funk on the Berberine. Also, there is some evidence that lowering protein may help, and there has been a lot of discussion of that recently in relation to the Sugar Diet (which has been around for decades but has recently be re-publicized). It's not something I think it is viable...
  26. G

    Building a TRT protocol around hCG

    I'm increasingly thinking, both from my own experience and observing others, that what you are describing makes the most sense, but with the addition of other targeted compounds to address specific issues. In your case, a moderate dose of Oxandrolone to replace the "lost" T seems logical (or...
  27. G

    High HCT low iron

    The time for high Vitamin C supplementation no matter what is if you feel any kind of infection/illness coming on. Especially Liposomal Vitamin C. Vitamin C is like the ammo for your innate immune system "gun". It's interesting that it may have raised your HCT since some of us struggle with...
  28. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Thanks for posting this. One of the big problems with what I'll call the Minimally Suppressive Testosterone/SERM approaches is the lack of publicly available discussion on the results of such experimentation, so it's interesting to see your results. I had never heard of L-Tyrosine creating those...
  29. G

    Severe Muscle Pain from Crestor?

    I have found that the 250mg version doesn't have even 1 quarter of the flush off the 500 version, so I have switched to taking more of the 250's.
  30. G

    Damage to my penis... please help

    It can make some people smell like Garlic for a little while although I've never had this issue. It does not affect libido. You have to make sure the skiin is clean in the area you apply it. AMidwesternDoctor on substack has done a massive series on it and I suggest you read that. It can...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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