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  1. G

    On TRT: How to check the state of cardiovascular system & how to find heart specialist

    For K2, I take either 2-3 MK-4 capsules with 100mcg each per day, or 100mcg Mk-7, however I suspect a higher dose of MK-4 would be fine. Some people APOE4's I think can build up too much K2 so I stay at moderate doses since I don't know if I'm in that category. For Lp(a), the best advice I've...
  2. G

    Interesting injury

    This sounds like a reminder of the importance of doing something for all body parts, even ones most people normally don't think about. If you are lucky enough to train at a gym that has a 4-way neck machine, it is a great, essential movement IMO. Otherwise you can buy a neck harness to use with...
  3. G

    On TRT: How to check the state of cardiovascular system & how to find heart specialist

    You might also check Lp(a). There isn't AFAIK a perfect fix if it's elevated although Oxandrolone apparently will help, but you could be at greater risk if it's elevated and hence might want to take more extreme measures
  4. G

    Thinking about TRT and could use some guidance

    My two cents: - Stop the finasteride and go to topical - It's way too soon for TRT. HCG or Clomid/monotherapy would be much lower risk, but may not be necessary either. You could add a low dose of oxandrolone to that if gym performance is still a concern at that point - Are you using viagra or...
  5. G

    On TRT: How to check the state of cardiovascular system & how to find heart specialist

    This is a huge topic but here are a few things to start with. I recently heard the results of a large sample of data correlated with heart events, and the number one risk factor was A1C, which should be under 5.5 or hopefully lower. This makes sense since elevated blood sugar can damage the...
  6. G

    Vitamin D May Slow Cellular Aging

    Yes, I'm a huge believer too and have heard many positive reports. Just be sure to take some vitamin K2 as well so that you don't get any calcium deposits where they're not supposed to be.
  7. G

    Vitamin D May Slow Cellular Aging

    IMO, Vitamin D plus k2 is worthwhile just for the benefits to the innate immune system alone. Everything else is a nice bonus. Above 50 is apparently the sweet spot. Pneumonia is a fairly big risk for may of us.
  8. G

    HCT and blood donation

    Bloodletting tends to correlate with longer life and there are some fairly exotic theories as to why. One of the simpler benefits is that it reduces the chances of Iron overload which is something you certainly don't want.
  9. G

    Can blood work be incorrect?? Really confused

    Regarding the breathing issues, something you may want to look into is nebulizing hydrogen peroxide. You need to dilute it with saline, but I saw it have incredible affects during Coivd, restoring people's breathing to normal within a matter of minutes. Do your own due diligence but it seems...
  10. G

    Vitamin E, an Antioxidant, As a Possible Therapeutic Agent for Treating Pain

    The boswellia definitely seems to help me with my hip, leg and knees. I had not heard of black seed oil for inflammation but have some so I'll give it a try. For joint pain, the Gunthers methol rub and diclofenac gel both seem to help a lot, as well as BPC 157.
  11. G

    Vitamin E, an Antioxidant, As a Possible Therapeutic Agent for Treating Pain

    The Vitamin E gurus emphasize that a full-spectrum Vitamin E should be used that includes all Tocopherols and tocotrienols. Chris Masterjohn recommends the Tocosorb brand. Also, I have noticed benefit from Boswellia, something that gets very little publicity. Curcumin can help too and has...
  12. G

    Can blood work be incorrect?? Really confused

    It sounds to me like the root of your issues is not hormonal, but hopefully Defy can still help with that. There is a lot of info in TRTGUY9's thread about chronic fatigue and brain fog. Ideally you can find a good holistic/integrative doc but there are not too many out there. You may want to...
  13. G

    Can blood work be incorrect?? Really confused

    Is there a dosage/protocol where you consistently feel/perform well? My two cents is that when all else fails, get into a state where you look/feel/perform well and if numbers like HC aren't optimal, manage it as best you can but give them a year or so of monitoring and see how they vary over...
  14. G

    7.5mgs daily labs

    Also, depending on what dimension you need/want further improvement on, there may be approaches other than more T to achieve what you need.
  15. G

    New to TRT. Received first labs. Concerned and need help.

    Yes, donating blood will briefly lower HCT, however there are other benefits, the primary one being prevention of iron overload. The is some mechanism by which long runs apparently lower iron, however other than that, bleeding of some form and chelation, there is no way to get rid of iron, and...
  16. G

    Can blood work be incorrect?? Really confused

    As someone who's had some unexplained variation in test numbers myself, there's something to be said for staying on a protocol for while that in theory should work, and then seeing how your numbers align over a few measurements. My HCT was elevated and then dropped right back down after a while...
  17. G

    New to TRT. Received first labs. Concerned and need help.

    Three more random thoughts that occurred to me... - You might want to have one of the hair analysis tests done that measure mineral status. They're fairly cheap and might give you hint at an issue - If you have access to a sauna at your gym it is worth trying since sweating is one of the body's...
  18. G

    Hello from NC

    Something else you might try is just to stop altogether for about 10-15 days. If things dramatically improve at some point during that time, that would be a clue that your sweet spot is somewhere lower and you can restart at a lower dose. In my early days of TRT I used to come off for a couple...
  19. G

    Updated Labs - Help Please

    IMO, if you are in a generally good place, I would stay where you are for a while and see if your e2 improves over time. It's hard enough to get symptoms sorted out, let alone trying to optimize numbers as well. It's impossible for me to tell if the brief supplemental e2 possibly reset my...
  20. G

    Updated Labs - Help Please

    I've had issues with unexplainably low E2 as well but it seemed to resolve after a while and rose to more normal levels (a while being a year or so). A lot of things I wouldn't have expected can interfere with the aromatase enzyme, such as zinc, so you might want to review you supplements and...
  21. G

    New to TRT. Received first labs. Concerned and need help.

    How about starting a thread dedicated to whatever it is you're arguing about and leave this and other threads to the specifics of the OP's topic. This has become like bar fight that spills out of one bar and goes up and down the street into other bars. My contribution to that thread would be...
  22. G

    New to TRT. Received first labs. Concerned and need help.

    It's way more nuanced. Some compounds, specifically Anadrol, are well-known to make people look red. There are plenty of people who likely have high-blood pressure. The "dry" look of thin subQ fat layer can make some people look red. Boldenone can raise HCT. and increase vascularity. But the...
  23. G

    Can blood work be incorrect?? Really confused

    There are other options. What issues are you looking for the TRT to resolve?
  24. G

    Can blood work be incorrect?? Really confused

    For results that extreme, my approach is to immediately test again if possible and assuming no symptoms. I had elevated HCT for a while and I can say that it is essential that you be fully hydrated to get an accurate test. I would schedule your tests late morning and drink at least half a gallon...
  25. G

    Advice and next steps. 38 years old with 305 total t

    First, IMO, there are many things you need to explore before going on external T. It is nowhere near as simple as many make it out to be. Since your sexual function is still fairly good, I would be doubly cautious because, as many men have reported, TRT can mess that up and not have it resolve...
  26. G

    New to TRT. Received first labs. Concerned and need help.

    Sparky's comments remind me that intestinal permeability (leaky gut) could be at play here too. There are tests for that (LPS?) but it seems better to just follow a protocol that would cure/prevent the leaky gut, such as Dr. Gundry's Gut Check protocol.
  27. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    In general, poor health is accompanied by a decline in Nitric Oxide production. The Viagra class of drugs blocks an enzyme that breaks down nitric oxide so it indirectly increases Nitric Oxide if someone is producing good amounts in the first place. Dr. Kendrick points out that these drugs far...
  28. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    I do too many things to list but I made a very quick starter list below. While the book has as section on specific recommendations which, for example, caused me to start niacin again and measure LP(a) and homocysteine, the bigger impact for me was that by better understanding mechanisms of harm...
  29. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Taking magnesium, K2 and vitamins A, K and E (full spectrum) may help absorption, but that sounds strange. Some infections "hijack" vitamin D, but I really just don't know. You might look into Chris Masterjohn's writing on the topic particularly around interaction with the parathyroid hormone.
  30. G

    New to TRT. Received first labs. Concerned and need help.

    Some comments in no particular order. - Your Vitamin D reminds me that there are apparently some infections that use the Vitamin D receptor as an entryway into cells, and for those infections Vitamin D can make actually make things worse. Dr. Michael Ruscio (who you should also look into) did a...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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