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Ask Dr Rand McClain

My supplements change depending upon my goals, time of year, activities, stress levels and other variables. I can say that in my experience, everyone needs supplemental B vitamins and vitamin D3. Remember the Kreb (Citric Acid) Cycle? Need B vitamins, magnesium, zinc and coenzyme Q10 to convert...
- Rand McClain DO
- Post #10
- Nov 23, 2017
- Forum: Questions for Specific Doctors & Experts
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Ask Dr Rand McClain

In addition, the timing of your dose of anastrozole is important. You might want to try varying the timing of dosing, eg: instead of taking your anastrozole when you inject your T, wait 12 or 24 hours before taking your anastrozole.
- Rand McClain DO
- Post #9
- Nov 23, 2017
- Forum: Questions for Specific Doctors & Experts
R
Ask Dr Rand McClain

I believe the issue is simply a matter of dosing your T versus your anastrozole appropriately so that your E2 stays in the range that works for you. Most of my patients inject weekly with satisfactory results (and 100% fewer injections). I would consider trying this simply because you have...
- Rand McClain DO
- Post #8
- Nov 23, 2017
- Forum: Questions for Specific Doctors & Experts
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Ask Dr Rand McClain

We, the medical community, are gaining more information regarding prostate cancer and testosterone use geometrically rapidly since Dr. Morgenthaler pointed out the flaws in the study that was the basis for which 70 years of dogma re testosterone causing prostate cancer was made. We now have...
- Rand McClain DO
- Post #7
- Nov 23, 2017
- Forum: Questions for Specific Doctors & Experts
R
Ask Dr Rand McClain

Hi All, Just want to jump in and say welcome and get started. Please shoot any questions you may have by me via the thread and I will touch base a couple times a week to do my best to answer. Best, Rand
- Rand McClain DO
- Post #3
- Oct 16, 2017
- Forum: Questions for Specific Doctors & Experts

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038