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  1. nakedjoe99

    Water Retention Caused by Testosterone May Have Nothing to Do with Estradiol

    I also take metformin. 1000mg XR morning and night. I actually started this protocol to see if it would help with water retention. It actually did work for a while. But, that could also be because it gave me severe diarrhea. After my gut became accustomed to the drug, I noticed decrease effects...
  2. nakedjoe99

    Water Retention and Rapid Weight Gain Caused by Testosterone

    Great! Thanks for the advice, everyone. I'll keep you posted on my progress and if I see any changes.
  3. nakedjoe99

    Water Retention and Rapid Weight Gain Caused by Testosterone

    You do daily injections with a 25G? Why don't you like insulin pins? Did you also have a problem with water retention?
  4. nakedjoe99

    Water Retention and Rapid Weight Gain Caused by Testosterone

    Wow that sounds too good to be true! Cant wait to try it. Does the ester type matter?
  5. nakedjoe99

    Water Retention and Rapid Weight Gain Caused by Testosterone

    I sure hope so. Ill give it a try. I just injected this morning so ill start this new ED protocol Sunday. I use the same syringe type. Do you rotate your injection spot? What ester are you using? Has this protocol worked for anyone else you know of for water retention?
  6. nakedjoe99

    Water Retention and Rapid Weight Gain Caused by Testosterone

    Vince, You're suggesting changing my 2x week protocol to ED or EOD will have an impact on my water retention? I searched the link you sent me but didn't find any connection with injection frequency and water retention. I know the broad picture here is to emphasize overall less side effects from...
  7. nakedjoe99

    Water Retention and Rapid Weight Gain Caused by Testosterone

    Hey, Vince thanks for responding. I've actually not gotten SHBG tested. Why do you suggest this? I split my 200mg/wk dosage into two 100mg doses.
  8. nakedjoe99

    Water Retention and Rapid Weight Gain Caused by Testosterone

    The peptides most certainly could add to the retention, but they are a more resent addition to my protocol within the past 2 months or so. I actually started them in a quest to see if they would help. This water retention issues has existed for years. The only thing that seems to help is a...
  9. nakedjoe99

    Water Retention and Rapid Weight Gain Caused by Testosterone

    Thanks for the welcome! OK, so: TRT: 200mg/wk Have not used any other compounds since about September of 2019. Currently also takind sermorelin, ipamorelin, cjc-1295 with dac, IGF-1lr3 No alcohol and no high salt consumption 37 years old Triglycerides:52 Fasting blood glucose: 98
  10. nakedjoe99

    Water Retention and Rapid Weight Gain Caused by Testosterone

    Yes, I have been using Lasix for years at a dosage of about 10 - 20 mg per day to deal with water retention from testosterone. it only slightly helps. I've been struggling with water retention for the past 10 years or so. Bloods don't show anything of value. I diet very well. I train 6 days a...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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