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  1. Systemlord

    Injection frequency & effects on other issues

    Nothing is a absolute in the hormone world. Give it a try and let us know. One thing to consider is oral T (Jatenzo/Kyzatrex) affects H&H far less than injections that only a very small percentage of men experienced high H&H in the clinical trials. You may be trading controlled H&H for low...
  2. Systemlord

    High SHBG, Low free T.

    My bad, I confused you with another member.
  3. Systemlord

    Switched to testosterone cream and was suprised at my blood e2 reading!

    Halving of dosages doesn't equal half the hormone levels. That's not how endocrine function works.
  4. Systemlord

    High SHBG, Low free T.

    You're probably infertile given that you were diagnosed with primary hypo.
  5. Systemlord

    Switched to testosterone cream and was suprised at my blood e2 reading!

    Why do you need E2 between 30-40? This is terrible, you must lower your dosage.
  6. Systemlord

    Hesitating on TRT, Does Anyone Have Regrets?

    You're dependant on food to sustain you, T is no different. TRT has less risks than remaining low-T, including decreased risk of prostate cancer.
  7. Systemlord

    T3 and muscle loss

    That’s because T3 (fT3) is what’s responsible for metabolizing testosterone on the liver.
  8. Systemlord

    Hesitating on TRT, Does Anyone Have Regrets?

    Many experts would argue that the bottom 25% percentile of the FT ranges is a sign of hypogonadism if you take into account populational averages.
  9. Systemlord

    Hesitating on TRT, Does Anyone Have Regrets?

    You're going to eventually lose that functionality in the not so distant future. To answer your question, I was on TRT for 8-9 years and HPTA function returned within one week. I'm 53 years old. All this for you is a moot point considering you have primary hypogonadism. There's no going back...
  10. Systemlord

    High SHBG, Low free T.

    Thyroid problems would present with low SHBG. Do you cut/starve yourself to look ripped? If so this can raise SHBG and lower testosterone production. This statement makes no sense. You can have a functioning HPTA and feel like normal everyday actively is akin to climbing Mount Everest...
  11. Systemlord

    Testosterone level

    I have similar TT and FT numbers. I'm 53 and the last time I checked my TT was 438, FT 8.4. I was on TRT for 8-9 years, came off and continued to have the same issues. I figured it out. The entire time on TRT I had low vitamin D but any time I tried raising the vitamin D I had side effects that...
  12. Systemlord

    Warning for Men on TRT: Low Ferritin is Bad

    A lot of mainstream medical doctors are ignorant when it comes to lipids. If doctors did receive nutritional education in medical school, the pharmaceutical companies wouldn’t be able to push their statins on people because the doctors would know better, and correct nutritional advice would be...
  13. Systemlord

    Warning for Men on TRT: Low Ferritin is Bad

    Correct me if I’m wrong but mainstream medical doctors recommend red meat once or twice a week. Insanity!
  14. Systemlord

    Lab results

    What do you have against red meat my friend? Chicken is too lean in fat to sustain you. I'm not seeing a healthy amount of animal fat in your diet. Big mistake! Humans are Apex predators, top of the food chain. Most of the animals that eat primarily meat are at the top of the food chain...
  15. Systemlord

    Lab results

    You don't give up much information and that doesn't gives us anywhere to go. Nothing mentioned about your diet/lifestyle. This is where mainstream medical doctors are practically useless. These symptoms of yours aren't specific to one disease and many doctors aren't good at troubleshooting...
  16. Systemlord

    Lab results

    You do have medical problems or you wouldn't be having these symptoms so early in life. There are a lot of medicine conditions (low cortisol/adrenal fatigue) that can cause symptoms mimicking low-T. Thyroid problems is doubtful given you're not overweight or have low SHBG. Full list of...
  17. Systemlord

    Struggling with bloodwork consistency. TRT bloodwork included.

    Many insurance providers don't cover (hCG) fertility treatments.
  18. Systemlord

    New here! Looking forward to learning and providing my experience as well

    Your protocol is terrible. No wonder you're having issues. The newer oral testosterone, Jatenzo, Kyzatrex have less side effects than injections due to the frequent dosing and shorter half-life.
  19. Systemlord

    DHT: How High is Too High

    Hair loss isn't solely due to high DHT, it's a contributor but not the primary cause of hair loss.
  20. Systemlord

    Struggling with bloodwork consistency. TRT bloodwork included.

    The AI can deceive you into thinking your estrogen is fine, when in reality, serum E2 means very little. Estrogen is converted, made in tissues (50 x higher than serum levels) which can't be measured and this it's where estrogen exerts its effects and you're blocking estrogen inside the tissues...
  21. Systemlord

    Maximus Native T: Gel vs Oral

    https://tctmed.com/trt-increased-strength/#:~:text=The%20results%20of%20those%20studies,total%20body%20and%20arm%20strength.
  22. Systemlord

    Maximus Native T: Gel vs Oral

    You would need to apply minimum daily due to the very short half-life.
  23. Systemlord

    Doc prescribed TRT - drop HCG?

    The thing about hCG is it increases other hormones and can create hormone imbalance or in the case where men show great benefit can create hormone balance.
  24. Systemlord

    Doc prescribed TRT - drop HCG?

    I never heard of penis shrinkage from not using hCG. That's a new one. As far as testicle shrinkage, depends on how big they are to start with, if their small, than any shrinkage is going to be more noticable. There are lots of men on TRT in isolation doing very well with no complaints. HCG...
  25. Systemlord

    Hello…. Looking for advise

    I updated my post. ^^^
  26. Systemlord

    Hello…. Looking for advise

    You’re overweight for a guy that’s 5’ 11”. Clean up your diet and exercise. If you really want to improve your health, the carnivore diet has the ability to boost your testosterone. Nothing increases testosterone more naturally than red meat and exercise. I don’t think a lack of testosterone is...
  27. Systemlord

    Beard growth/face changes and TRT protocol - just me?

    If you're experiencing overstimulation due to the half0life of injections, lowering the dose won't matter. Changing the delivery method/half-life is the only option.
  28. Systemlord

    Beard growth/face changes and TRT protocol - just me?

    I didn’t notice a difference in my ratios of other hormones at midpoint and peak on injections versus orals. The only thing that changed was the half-life and the large fluctuation in hormone levels. The medium half-life injections can cause overstimulation because level stay elevated longer...
  29. Systemlord

    Beard growth/face changes and TRT protocol - just me?

    Perhaps you’re overdosed on IM. Try lowering your dose if you go back to IM.
  30. Systemlord

    New Member -- Will Take All the Advice I Can Get; Initial Questions re Dose

    I never felt right on injections. The shorter half-life formulations really change things for me. My natural levels more closely mimic the shorter half-life formulations. The difference between early morning and late afternoon are dramatic.
  31. Systemlord

    New Member -- Will Take All the Advice I Can Get; Initial Questions re Dose

    This is one of the reasons why many men continue to struggle with TRT. As of right now your hormone levels are unsteady. If you were on Jatenzo or Kyzatrex, you'd reach steady levels in 7 days due to the shorter half-life.
Buy Lab Tests Online
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic

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