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  1. Dr. John Crisler

    Quest Diagnostics Ultrasensitive Estradiol Code

    The aforementioned thread by Nelson is a great post, emphasizing you MUST run the more sensitive estradiol assay. The standard assay is not valid for adult males, and usually over-estimates the true E concentration. This may lead to inappropriate use of an aromatase inhibitor, to the detriment...
  2. Dr. John Crisler

    Quest Diagnostics Ultrasensitive Estradiol Code

    The code, and range, provided in this thread: Suggested Lab Tests and Questions Before and After Initiation of Testosterone Replacement ...needs an edit. The proper code is 30289, and range is "<29" (I am unable to reply to that thread directly)
  3. Dr. John Crisler

    Estradiol (standard vs. sensitive)

    I see numbers...but not a word about how you FEEL...
  4. Dr. John Crisler

    Estradiol (standard vs. sensitive)

    Right, Nelson, and compounded (pun intended) by the fact they treat to numbers, not actual symptoms. IF there are no elevated symptoms, I do not add an AI.
  5. Dr. John Crisler

    Estradiol (standard vs. sensitive)

    That's pretty common, as the Standard assay greatly overestimates the actual concentration of E2.
  6. Dr. John Crisler

    Gynecomastia: Clinical evaluation and management

    Without further evaluation--including labs--it's not possible to say. But nipples which are increasing in size is indeed a sign of gynocomastia. Since we talked about it, I hope the estrogen test is appropriate for an adult male; that is to say an enhanced laboratory methodology. IF the...
  7. Dr. John Crisler

    Can Testosterone Induce Blood Clots and Thrombosis? Interview with Dr Charles Glueck

    Have they been shown to be so in adult males? Or is he extrapolating? All these years, hundreds of patients, and not a single event while on Arimidex.
  8. Dr. John Crisler

    Can Testosterone Induce Blood Clots and Thrombosis? Interview with Dr Charles Glueck

    Have they been shown to be so in adult males? Or is he extrapolating? All these years, hundreds of patients, and not a single event while on Arimidex.
  9. Dr. John Crisler

    Can Testosterone Induce Blood Clots and Thrombosis? Interview with Dr Charles Glueck

    How much faith do we have in the 1-2% incidence claim? IF there is going to be an issue, he says it will show up in the first 3 months. This sure does warrant an additional two questions on Medical History (personal and Family Medical History).
  10. Dr. John Crisler

    Can Testosterone Induce Blood Clots and Thrombosis? Interview with Dr Charles Glueck

    How much faith do we have in the 1-2% incidence claim? IF there is going to be an issue, he says it will show up in the first 3 months. This sure does warrant an additional two questions on Medical History (personal and Family Medical History).
  11. Dr. John Crisler

    Can Testosterone Induce Blood Clots and Thrombosis? Interview with Dr Charles Glueck

    "1-2% of men taking T will develop blood clots related to underlying inherited clotting abnormalities or to acquired thrombophilia (the antiphospholipid antibody syndrome)." I have not seen a single case of this in a dozen years of prescribing TRT, including use of anastrazole, on a daily...
  12. Dr. John Crisler

    Can Testosterone Induce Blood Clots and Thrombosis? Interview with Dr Charles Glueck

    "1-2% of men taking T will develop blood clots related to underlying inherited clotting abnormalities or to acquired thrombophilia (the antiphospholipid antibody syndrome)." I have not seen a single case of this in a dozen years of prescribing TRT, including use of anastrazole, on a daily...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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