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  1. T

    Very long term TRT (20+ years) - risk of liver cancer?

    But my A1C is perfect, and my glucose has been perfect. I did not check my glucose for the past 2 or 3 weeks while on the scrotal cream though. But like right now, my glucose is 78. With that said, I do feel like I get postprandial hypoglycemia, especially when my T is up. It's just not showing...
  2. T

    Very long term TRT (20+ years) - risk of liver cancer?

    I just got my test results in. Just 25mg of scrotal T cream caused my DHT to shoot up to 181, over the range of 12-65. E2 was only 13 (<= 29), serum T was only 292, and Free T was 67.3 (35-155) LC/MS-MS. With my DHT being way over the top range, I wonder if that was somehow making me feel dizzy...
  3. T

    Very long term TRT (20+ years) - risk of liver cancer?

    This happened in 2007 when I tried it from a different compounding pharmacy, but that had chrysin in it, and I thought maybe that was the problem. But this is just Versa base and T. I feel miserable.
  4. T

    Very long term TRT (20+ years) - risk of liver cancer?

    Update: I have been trying scrotal T cream for two or three weeks and I feel like complete shit. I'm dizzy, feel tired (like I could pass out), I'm super weak, and overall I just feel terrible. I wanted this to work, because I was tired of needles after 20 years. But after feeling like I have...
  5. T

    Very long term TRT (20+ years) - risk of liver cancer?

    Right, Nelson is going strong. I know a handful who have done TRT 20-30 years, also doing good. But most of the people I know never went crazy with danazolm, anadrol, dbol and other stuff. I'd guess those who used TONS of 17α-alkylated steroids in the past are more likely to be on TRT at the...
  6. T

    Very long term TRT (20+ years) - risk of liver cancer?

    I've been on TRT for about 15 years. I keep my total testosterone on the low end, around 400 (I couldn't get my T over 150 before TRT). This evening I was reading this study: S2577 Development of Liver Cancers as an Unexpected... : Official journal of the American College of Gastroenterology |...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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