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Metformin Lowers Testosterone?
I posted my T labs above. I think it's pretty obvious Metformin had a sustained down-regulating effect on my levels. I will test again soon to see if it leveled off. How many others have seen their T levels plummet when on Metformin (on or off TRT)?- mcs
- Post #13
- Forum: When TRT Is Not Enough (ED, Libido, & More)
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Metformin Lowers Testosterone?
It definitely tanked my levels (see below) and I would advise the anyone who's not T2D be aware of this and perhaps not take it unless you're hormonally optimized (on TRT). June, 2022 (pre-Metformin): TT: 553; FT: 76.9 August, 2022 (1 month Metformin): TT: 415; FT: 70.2 November, 2022 (4 months...- mcs
- Post #12
- Forum: When TRT Is Not Enough (ED, Libido, & More)
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Latest Update on Metformin
My joint pains have worsened to which I attribute both low T and E2 symptoms. I think it's obvious I should d/c the Metformin until I get my hormones optimized.- mcs
- Post #108
- Forum: Health & Wellness
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Latest Update on Metformin
5-7 180lbs - but even when I weighed 20lbs less, my BP did not lessen. Have tested my DNA extensively for hereditary clotting issues and nothing came up except MTHFR. I feel I need be on TRT at this point and think I should d/c the Metformin for now until my T levels are optimized. Maybe start...- mcs
- Post #105
- Forum: Health & Wellness
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Latest Update on Metformin
low 100s if I don't fast for at least 12h, in the mid to high 90s if I do. If I eat even complex carbs for dinner, FBG will go into the 110-115. A1C 4.9-5.2. Metformin doesn't seem to influence those numbers either way. I take 1g with last meal and 500mg before sleep.- mcs
- Post #104
- Forum: Health & Wellness
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Latest Update on Metformin
Observations being on ER-Metformin for last 4.5 mos. (started July 1, 2022) 15lbs weight loss - no change in diet or training No GI problems up to 2g/day No change in fasting glucose levels or a1c (not diabetic to begin with) *Substantial decrease in total and free T (not on TRT): June...- mcs
- Post #101
- Forum: Health & Wellness
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TOO MUCH T3 FROM NDT = JOINT PAIN?
Yes.- mcs
- Post #19
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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TOO MUCH T3 FROM NDT = JOINT PAIN?
Observation - Progressive increase in blood pressure/pulse averages: last 12 mos: 127/79/63 last 6 mos: 126/80/64 last 3 mos: 128/82/68 last mo: 131/84/67 causes: increasing NDT>increased serum T3 = elevated BP/pulse?- mcs
- Post #17
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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TOO MUCH T3 FROM NDT = JOINT PAIN?
Have been doing it before for the last several labs this year to measure the effect of the dose.- mcs
- Post #15
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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TOO MUCH T3 FROM NDT = JOINT PAIN?
When you say to keep your FT3 levels high, how high? I, too, have lately been doing my labs the same morning I take my NDT dose to see how the medication is working. And it is working as I can tell from the labs I posted on above. I guess I shouldn't be concerned with being a bit over range on...- mcs
- Post #13
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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TOO MUCH T3 FROM NDT = JOINT PAIN?
That one relates to TSH over-suppression. Fortunately, not my problem. In fact, my issue has been high normal TSH and trying to suppress it more by gradually increasing the dose of NDT which it appears I have done. That latest level of 1.23 is right around where I need to be.- mcs
- Post #11
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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TOO MUCH T3 FROM NDT = JOINT PAIN?
Didn't get rT3 tested this time, but I usually hover around 19 (but that was at a lower dose of NDT). Will test again soon. What I really am curious to know is whether too much T3 can accelerate cartilage degeneration which would give rise to OA and injuries. Maybe it's completely unrelated...- mcs
- Post #8
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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TOO MUCH T3 FROM NDT = JOINT PAIN?
Never have had an indication of Hashi's from dozens of past labs and ultrasounds and as I indicated, I am on NDT, not Synthroid.- mcs
- Post #7
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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