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Can you suggest Estradiol valerate oral dose ? I have low estradiol (in 20s on 200 mg a week of test e and 500 iu HCG EOD protocol. Off the chart freeT and DHT. SHBG 20-25 ) Would it be any better to take estradiol valerate in injection form ?

Thanks a lot

My SHBG is 22 And total testosterone 5.72 ng/ml but these are tested with ECLIA method . Can they be used as valid entity in calculator ?

Sorry, I didn't understand the complexity of your last sentence . Are you trying to say RIA gives exaggerated values as compared to equilibrium dialysis ?

Problem is that they use same RIA method for SHBG and total testosterone as well . So I guess everything becomes unreliable now. Lol Btw does RIA gives exaggerated values compared to equilibrium dialysis ?

I don't have equilibrium dialysis assay in my country and they test free testosterone with RIA or CLIA method only So my recent free testosterone (RIA method) was 49 pg/ml ( 12-40 pg/ml) This says I am over the reference range . Should I take this for face value or assume the assay is flawed ...

What was your hcg dose when you felt like it increased tour thyroid activity?

https://www.sciencedirect.com/science/article/abs/pii/S0378512203001476 Can DHEA, if supplemented, increase progesterone in men on trt ?

How much time after starting HCG did you go for lab testing your thyroid and dhea levels ?

How much time after starting HCG should we test for DHEAs and serum estradiol to check if it has any effect on it ? Considering 500iu EOD of HCG .

One more question I don't have sensitive estradiol test in my country . Is there any way I can create regular estrogen with US estrogen ?

Please explain e3d . If I inject HCG on Mondays, e3d injection would be on Thursday ?

So what shall be the HCG dose for men above 66 years age amd those on long term TRT ?

Isn't the bioavailability of progesterone (oral) just 2.5% ?

What's the bioavailability of this cream ?

Ok

It said free e2 might be lower. So can i conclude i have low e2 coz i have all the low e2 symptoms ? And what should i do to increase it ?

DNP is king of improving insulin sensitivity, yet it does so little to bring up SHBG

Evene Even amiloride causes sexual dysfunction/libido issues. Mentioned on many websites .

Won't you aromatize a lot more to E2, since u have low SHBG?

Does trestolone crushes SHBG as well ? Or one can use it and still see an increment in SHBG score ?

Doesn't DHT also lower SHBG .

But would the SHBG still in the dumps while using ment or dhb ?

Can you explain how this doesn't affect low SHBG ?

Does ment crush SHBG ?

Did trestolone or DHB suppressed SHBG ? Were you able to get up SHBG numbers while on ment or DHB ?

Does that also mean it wont crush SHBG like other androgens ?

Anu evidence that trestolons doesn't bind to SHBG