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If your free testosterone is optimal, which I doubt that it actually is, then you need to be looking at thyroid. That's the real problem. Everybody wants to attribute everything to testosterone and then when it's not going right for them, blame it on estradiol. You do realize that most of the...

Good to hear, but just understand there is a plateau to the feel good effects of testosterone. That plateau is whenever the androgen, receptors, and more importantly, the estrogen receptors are fully saturated. Raising testosterone past that point will only result in excess, but yes, it will...

And also, you do realize that when you measure estradiol, you're measuring a snapshot in time. If you were to measure it eight hours after you did, it would've been a different number. Trying to compare and estradiol level doing injections and then comparing it to cream is futile. The number is...

You increase estradiol by increasing free testosterone. That's how you do it. I don't see any reason why someone would need to add injections. In the right hands and utilizing a properly compounded cream the levels are at times equivalent to what one would have to inject 3 to 500 mg of...

Until you understand the difference between giving pure DHT and raising DHT by giving testosterone you will not understand. There is a difference. Ma ̊rin et al. compared the effects of transdermally applied T and DHT to a transdermal placebo treatment on changes in body composition and...

Actually, we been using testosterone 85 years and I think by now we realize that it's safe. This is nothing but simple physiology. There is actually a plateau affect with regard to taking testosterone. There's a point in which it's not going to make someone feel any better. That is the...

HCG doesn't boost estradiol levels while on testosterone. While on testosterone, it maintains intra-testicular testosterone levels there for maintaining spermatogenesis. It doesn't do anything for estradiol. When not on testosterone, it will raise testosterone levels, therefore, raising...

Please provide evidence of everything you just wrote because it's a bunch of nonsense. It's not based on any medical literature whatsoever or even physiology. Do you even take the time to read a study such a studies where they gave DHT to men for years and raised it 10 to 20 times normal? What...

You somehow missed the boat on this one didn’t you? We are talking about specifically men that take testosterone and raise the DHT in the serum and the serum levels do not have any physiological effect. Testosterone enters the cell and is converted to DHT where it binds to the receptor. Once...

Had absolutely nothing to do with the DHT you measured. Had nothing to do with DHT at all. The DHT you measured had no effect at the cellular level. It was not the cause of your symptoms but you will blame it...

Here's the problem with forums. You know nothing about the OP other than what he chose to tell you. Part of what he chose to tell you is that he's had headaches all of his life. What in the world does it have to do with testosterone? You know nothing about any work up that he's had. Has he had...

No that's not necessarily true. The literature is there the problem is people don't know where to look or how to look. Most just don't take the time to look. It takes a lot of time and dedication. It just can't be done via Google or worse... abstract surfing. People have to look outside the...

If a doctor practice is purely evidence based medicine and only medicine based on the medical literature that is a purely scientific practice. It is those that make recommendations that aren't evidence-based that don't have any medical literature to support why they do what they do that are...

It's not that fast. It's not that fast at all. Whatever happened to you wasn't from the cream and peaking within seconds. Wherever you got your cream from wasn't any good and that's always a major problem with many compounding pharmacies. You weren't feeling a decrease in three hours you were...

Make sure you get the units of measure right. It may be 5000 but that would be a picograms per milliliter which correlates to 500 ng/dL. Yes, a lot of men have DHT levels 500 and more (5000 and more pg/ml) but those levels have absolutely nothing to do with what's going on at the cellular level...

Baseline observations do not apply to men on testosterone. When we give testosterone to men that are highly inflamed and obese and raise their hematocrit it improves their health and it's never been shown to cause harm. The US Navy has a normal hematocrit up to 61 in their labs

Because they have been trained to think that way. But it doesn't work that way. These men that complain of such have comorbid conditions. This is the problem with forums is that you don't know the complete medical history of individuals that post. Athletes increase their hematocrit because it...

NOT IN MEN ON TESTOSTERONE. Baseline observations do not equate to men on testosterone.

Can't help but take the bait, but how does hematocrit affect your ability to recover from exercise? What is the mechanism or physiology behind that? When did an increase in hematocrit cause fatigue? Why do we have our olympic athletes train at high altitude to cause a secondary erythrocytosis...

Ahhh, once again, a baseline observation that has nothing to do with men on testosterone and what testosterone does. What are you reporting has absolutely zero to do with middle testosterone, and how it affects vascular activity. Let's stick to testosterone and the secondary erythrocytosis...

If utilizing testosterone for 85 years and the most common side effect is a secondary erythrocytosis which hasn't caused an epidemic of heart attacks, strokes, clots , or any disorder, then I don't know what more you need to be convinced. Would 100 years be adequate? Wasn't that long ago we...

I have commented on that author's comments multiple times. He can't produce anything at all related to testosterone and raising hematocrit causing harm. Not a single and I mean not a single piece of literature. Testosterone Therapy as a cause of Secondary Erythrocytosis The most common side...

Terrible information you were recommending and it's not based on men on testosterone or men living at high altitude that also have a secondary erythrocytosis. BASELINE ELEVATIONS IN HCT IS NOT THE SAME AS THE SECONDARY ERYTHROCYTOSIS FROM TESTOSTERONE.

No, it's not. It's actually the truth. Testosterone does not cause blood clots and it never has an 85 years of use. Do young men with high testosterone levels get blood clots? Testosterone has never been shown to cause blood clots in any randomized controlled trial to date. When you evaluate the...

its not the DHT

none...none at all. Please read article madman posted above on the physiology of DHT.

You should already know why he is wrong. Don't forget, he is also in a medical institution and therefore subject to all the restrictions it involves in prescribing testosterone. He is my favorite urologist but he is also subject to staying within the mainstream bounderies and follows the...

And he is wrong

Remember what you were measuring in the serum is excess and does not have any affect at the tissue level. Testosterone enters the tissue and is then converted to DHT where it then binds to the androgen receptor and then his translocated to the nucleus etc. The saturation point is the point in...