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Since both Clomid isomers are excreted primarily (50%) via the gut Cal-D-Glucarate shouldn't have much affect since it works at the renal(kidney) level to increase glucuronidation of different chemicals/hormones. A mere 8% of clomid excretion appears to take place in the kidneys. It certainly...

I linked to my sources, might have missed one. I'd been writing this up in Word and its now to the point I thought it would be useful to share.

Part One: Clomid Introduction - Selective estrogen receptor modulator, which occupies e2 receptors acting as a weak estrogen - Two parts/isomers, 30-50% zuclomiphene(estrogenic) and 50-70% enclomiphene (non-estrogenic) (1) - Inhibits negative feedback of e2 primarily at the...

Interesting, how'd they reach that conclusion? I've assumed from my reading that Docs usually rely on actual response to dosing(clomid/hcg challenge stuff) to genuinely determine primary vs secondary.

Cut the cardio to minimal amounts and focus on using/building metabolically active tissue (muscle) if you want to get leaner. If not able to physically lift weights (injuries), be sure to rely primarily on cardio that utilizes a lot of muscle, ie. stairmill/stepper or inclined treadmill instead...

Hey partner, you should definitely reach out to a TRT service provider like defy or primebody who can link you up with a Doc in your area that's competent. If you total T was higher, I'd say you look secondary, but as your numbers exist, you could certainly have some dysfunction at the...

What's your dosage protocol? This is the first time having your low T addressed? You have great Free T, but I've heard it's around the Total T level of 650-700 that things actually start to feel better assuming free t stays in midrange. Looking forward to hearing more as I'm in a similar...

Here's a little more detailed analysis for those of you interested.

Not sure if it was a typo, but "calcium gluconate" is not indicated in estrogen management. It's calcium-d-glucarate that Saya and many others typically recommend. On e2, I've heard another Doc mention a 10:1 ration as the minimum they shoot for between free t:e2. So right now you're toeing...

On SHBG levels, indeed liver issues or diet can play a role there. One study on men found an inverse relationship between Vitamin D levels and SHBG. Have you Vit. D checked on next panel. On increased appetite, could be related to Clomiphene's effect on various brain regions that regulate...