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My question is really more theoretical. Again putting fertility issues aside, I'm wondering whether the positive effects of HCG are binary. In other words, if the testicles become normal sized again (after experiencing shrinkage) with a certain minimum dose, is that the maximum benefit someone...

Putting fertility issues aside, if you figure out the minimum dosage required to prevent or counter testicle shrinkage, would taking any more HCG provide any additional benefits? On TRT alone I definitely get shrinkage, but no pain. So I take HCG purely for cosmetic purposes, as I don't feel...

Thanks - I look forward to hearing your follow-up reports. Sounds like someone bottled water from the fountain of youth!

Just curious, and I apologize in advance if this is answered in some other thread, but what are you hoping to accomplish with Ipamorelin? I've just started to learn about all the various peptides, but for now they are just words to me.

What was your ferritin level when you had trouble sleeping? And what was the level when sleeping improved?

You're describing me before I got on thyroid meds. Have you had your thyroid levels checked?

Yes - blood draws both 3-4 hours after taking T3. I recently reduced the dose of T3, as I was feeling a little overmedicated. Not sure if it was all in my head after seeing the latest labs, but I found I had a pounding heartbeat and was more easily stressed by things that would normally not...

Pre T3 with 5 mg Lipitor daily: After a couple months on 30 mcg with 5 mg Lipitor: Then retested lipids after a couple of months after stopping Lipitor and increased T3 to 40 mcg/day: My cholesterol values did not move after being on TRT for a while. It was the T3 that had a...

No info on Pregnenolone but after about 4 months on T3 supplementation all my cholesterol numbers dropped by about 20% (chol, HDL, LDL, Triglycerides). I was able to discontinue Lipitor and everything is still within range.

Any update? I'm considering trying the same 'experiment'.

You ever try Modafinil? I've been using it off and on for years. For me its much more effective than caffeine. It's a prescription drug but you can get it overseas without.

Anyone ever try ESS60? I just listened to a podcast with the guy that sells it, and he claims it helps with sleep - among other things. The website is World Leader in Fullerene sales - Highest Quality ECS60 in Olive Oil

I get night sweats too, just not every night. I'm going to start tracking the night sweats to see if it correlates in any way with my E3.5D injection schedule. But the pissing is an every night problem.

Are you not worried about taking it long term? I guess its the sort of thing that if it starts bothering my stomach I could just stop.

Does not help me. I cut out fluids about 3-4 hours before bed, but still piss like a racehorse all night long. It seems to have gotten worse since TRT (or maybe its the HCG). Pre-TRT I would usually get up maybe once per night, but sometimes not. Now, 2 or 3 times per night - every night.

So I started with 25 mg of ***, and increased to 50 mg. It definitely helps, however I still have to pee 2 and sometimes 3 times per night, which wrecks my sleep - I always have a hard time falling back to sleep. Anyone have any success with supplements that reduce urine production (or the...

My primary care doc refused to prescribe Testosterone because she said "it leads to cardiac problems" - this was in spite of my bloodwork showing clinically low Testosterone on the LabCorp range. So I found an endo local to me who is fairly well known for TRT. After a few months of feeling...

I do the same. I feel like I'm hedging my bets, in case one method actually turns out to be superior over the other. I started out SQ, then switched to IM - felt absolutely no difference. So I decided to alternate between the two.

When you were jittery, did you notice your heart was pounding? I've been experiencing that, and was wondering if HCG may be the cause. But I've been taking 400 IU E3.5D for about 3 months and this pounding heartbeat issue only started very recently.

General question - when you guys refer to palpitations, are you talking about irregular heartbeats or pounding heartbeats? Within the last few weeks I started experiencing pounding heartbeats after 7 months on TRT and almost 3 months on HCG. It's very annoying, but the heart rhythm feels...

The T3 was prescribed by my current doctor. Started at 10 mcg, then increased by 10 mcg every 2 weeks until I got to 40 mcg. I was told to stop increasing if I felt any hyper symptoms, which I did not. I recently backed off to 35 mcg because that's one of the doses available in the extended...

Thank you. I will give it a try.

Do you find that you build tolerance to ***? I'm just wondering if that "cost per night" to get a good sleep will keep going up as time goes by.

Lakeguy - Your stats are similar to mine. I started TRT last December. Prior to that my running was limited to how my lower legs felt. I was able to run 2-3 miles before my legs ached so much that I had to stop (shin splint type pain). Since TRT the leg pains are gone any my running is now...

You mentioned in your initial post that you felt wired, so you stopped the meds. With those low FT3 numbers maybe it was caused by something else? I realize everyone is different, but my last FT3 was over 6 [2 - 4.4] and I don't feel at all wired. This was a peak level because my doc likes me...

Yes - Extended Release from Empower. As for the T4, my doc agrees with you. We're going to monitor things and adjust if necessary. I would like it to be more within the range, but I'm not going to chase a number if I'm feeling okay.

In hindsight, would you have started on T3 only, and then after you got your RT3 down maybe add in some NDT? I had RT3 of 23 - [9 - 24] before meds, and have been on 40 mcg T3 extended release for about 3 months. I feel much better and my RT3 is now 9. I'm wondering maybe I just stay on T3...

I almost always have trouble sleeping, but when I'm stressed out (family, work, etc) my sleep is terrible. I don't think its any worse pre or post TRT. I think for me it's more of an age thing (mid-fifties now). I've been considering adding *** oil before bed, but it seems as though the...

For T3 only treatment, what would you consider to be a "larger amount" of T3? I've been taking 40 mcg of T3 for 2 months (extended release from Empower), and my Estradiol went down slightly, and SHBG remained within its typical range for me. However after reading various articles posted here on...

Great info - thanks Gman.

Wouldn't T3 only push the T4 down even further? At what point does too little T4 become a problem? I'm dealing with similar issues - I thought I had a handle on how all this works, but the more I learn the more I realize I don't know . . .