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fair enough, but the lag effect might be significant for some i guess, one option is also that on the first day estradiol is welcome and by the second saturation of receptors would not be needed but e2 keeps on getting produced in quite similar rate even though testosterone gets released less...

The link you provided mentioned trt induced estradiol as the likely mechanism as well. It also makes sense, feedback loop gone etc. Well, this is why i am saying it's related to E2, on the injection day you have less since none is floating around from the days before. I will for sure check...

This is what i've been trying to say, i dont see turning to prolactin very useful when 99% sure it comes from too much estradiol in the system, probably many guys are able to blunt those effects by adding more t which makes the ratios better. If that is detrimental in the long run who knows...

ok thanks for the tip, can you tell me a little about the mechanism by which testosterone injection causes a delayed rise in prolactin, and IF prolactin is causing the symptoms why does more testosterone equal less symptoms? Also you are probably aware that raised estradiol can contribute to...

Also, further proof, when injecting 250mg of sustanon, the estradiol symptoms strike around day 3, when prop and phenylprop drop vane off. Have tested estradiol and it is not aromatizing at the same rate it does on smaller doses, that amount of sustanon takes t levels above 2500 briefly. So the...

If you were answering to me i'm not sure what you're referring to, it is clear as day that estradiol follows testosterone, so it makes perfect sense that on the injection day there is less estradiol present and for this reason i feel good in all areas. I feel worse the next day if the injection...

I would assume that is the case, can't think what else, but you know, on the injection day mood and libido are good, as well as sensitivity, sex feels better, next day not so much for any of those, start feeling better and less moody as the ester has started to decline and less estradiol is...

you dont think it could have something to do with poor t/e ratio, i have felt pretty bad with small amounts that result in physiological levels even when coming from hypogonadal levels, if the dosing was not done daily, but for example twice a week, the first day is usually good no matter the...

i would use the same muscles on both sides, even in the beginning, you have to get both sides driven in eventually anyway

It's the benzyl alcohol 100mg/ml in sustanon, when you inject the same muscle multiple times the pain usually subsides, some people are just more sensitive to BA and the only option is to use something else if the pain doesn't go away with time.

Do you think that the aromatase inhibiting effect of vitamin d contributes to the loss of vigor down there

https://pubmed.ncbi.nlm.nih.gov/19906814/

So you switched from bc pill to estradiol valerate?

Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes https://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30160-7?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413116301607%3Fshowall%3Dtrue

It's amazing how some can tolerate huge doses, while personally i can not take even 5mg much less 10mg without ruining the next day.

I guess the silence from OP means he happily resides in multiorgasm-land with his original protocol then :)

Do i remember correctly you are not taking any pregnenolone anymore?

You dont Peat? I´d like to know if @Systemlord has monitored blood glucose after the OJ? Ray Peat i guess was known to down a lot more at once.

Hi there, any update?

do you notice any difference if you include coffee or dairy products in your iron-rich meals?

Could there be some feedback loop that would cause LH to drop when a natural male is supplementing with high doses of pregnenolone? So just wondering if you could actually end up worse testosterone wise when not on trt, it seems the claim that preg supplementation increases or may increase...

How's your eggsperiment going?

If someone has both e2 and testosterone right at the lower limit of range, i don't know if it would be a good strategy, seems like all the participants had a decent e2 number to begin with. I have always had a low e2 in the natural state, hesitant to try anastrozole mono, but i guess trying with...

Well i can see if i find something, it's just based on anecdotes, almost everyone seems to say they last longer with these, and it is due to that feature, for some it might go overboard. You may find some useful information on the matter in general on here...

pde5 inhibitors like cialis and viagra are known to reduce sensitivity, i would take a long break to rule it out.

You used it with trt? You think in every scenario it's best used daily? HAlf life is quite long at 50hrs...

I wonder if they used the 1mg dose just due to it being 1mg and not available in smaller mg without splitting pills or was there some science behind it, would have been great to have one group on an even smaller dose, even so it still probably would lower e2 when a testosterone response is achieved.

Interesting, and congratulations on the recovery, may i ask if you were on test only or did you use hcg, and did it make any difference if so?

did you notice any change in testicle size dropping hmg?

How about body composition?

Did you ever experience anything similar from anything else, i wonder if its from GnRH directly or say pregnenolone or dhea?