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Did that occur with a different dosing protocol or with dailies?

Thank you. Sounds like me. I've been mixed state for several years/depression, along with bouts of anger & rage. To keep it short, I have a history of sub-clinical hypothyroidism and it was resolved when I was prescribed Cytomel in 1994, but after 11 years, I stopped responding to it. It was...

I'm just at the beginning of an experiment applying DHEA to my scrotum, partly for assessing if it will increase DHT and free T. Oral has always caused mood problems and worsens my sleep, which has been garbage for years due to bipolar illness, but my DHEA-S has been on the low side for years...

@Systemlord / I know you've been having great success with Jatenzo but not easy to get any of the oral versions of testosterone covered by insurance. Yes, one's doctor would have to write a letter to the insurance company. Their days are quite busy, even in a group practice like the one where...

You've been on testosterone for a year. Unless it's test propionate, you're not going to feel like crap in 2 or 3 days. Even with test prop I don't believe you'll crash in a couple of days.

THIS! OP, go on YT and listen to interviews or lectures by Dr. Neil Rouzier, one of the top docs in hormone optimization. He cites the research, too.

I understand. Just my sense of humor. My marriage has been a clusterfuck. I'll leave it at that.

Oh, brag about it, LOL!!!

Not a patient of Defy. Medicare covers labs under Part B,(doctors visits, labs, medical tests) which is what we pay each month(deducted from our Social Security check). When you go to Quest or LabCorp or any other lab, you'll present your Medicare card and Medicare supplement card. Years ago...

On T-Nation and Reddit, read many posts from guys experiencing various physical symptoms on Test C and I tell them it's either the oil and/or the preservative and that they should try Test E, particularly if they're under the care of a doctor. Yes, it is pricier. Even with using Good Rx, about...

As many of the men on here know, I've been on many doses and dosing protocols over the past 10 years, as well as cream and a round of pellets. I also have bipolar illness, CPTSD, non-restorative sleep and now almost 2 years into caring for my wife who has Alzheimer's. Been going to the same...

That's Hikma's Test E; formerly Watson-Ward(or the other way around).

I believe BB & BA are the reasons I never could tolerate Test P.(from Empower). Always would feel vaguely sick, like I'm coming down with a cold(scratchy throat, runny nose, malaise). Cottonseed oil in Test C produced the same symptoms. Test E; no problems.

I can't prove it. I can only go by what he reported. The closest to that was a guy on AllThingsMale.com . He was going to Dr. Shippen, on subq testosterone, with good lab numbers but poor erectile function. Dr. Shippen was as much a scientist as he was a doctor. He prescribed T cream with...

There was a guy who used to be on here and the old Yahoo testosterone group, @JanSz. He started out on some high dose of Androgel and it worked but his DHT went super high, resulting in prostate issues. Even with the generic versions of the various gels, IMO, one would have to use several tubes...

BigTex, thank you for the laying out the objective facts and unvarnished truth!

I have great respect for Highpull. He doesn't hype anything; just places the facts and data out there and readily admits there are aspects that have him puzzled, specifically, the declining testosterone numbers in young men, along with young men consulting with him who, though apparently...

I'm the end of the line. I never contributed to the gene pool. :p

Could the near doubling of E2 reflect injecting into fat versus IM? That seems to be a debating point since many men do sc but a concomitant rise in E2 isn't a given.

From our many conversations, I know you're plugged in to many sources of information and can discern what's legit and what's jive. I'm certainly keeping an open mind. Fast forwarding, my stress isn't going to be reduced. As my wife declines, I'll have a heavier load to carry. I know it's not...

@Gman86 /After our exchange, yesterday, my mind went back in time to the 1980s. In orthomolecular psychiatry, as well as what we'd now call 'functional medicine', doctors were using therapeutic fasting to treat or manage both mental and physical illnesses. My father, who'd been dealing with...

Is there an inference that subq is inferior or more problematic than IM or is it more related to the individual's response to subq regarding conversion to E2? Based on the research of Dr. Swerdloff, et al on subq versus IM test enanthate, the former demonstrated a half life of 10 days. I know...

I recall you suggesting a carnivore diet in regards to my illness. Dr. Emily Deans and Dr. Judy Tsafrir are the other two psychiatrists in Boston recommending a keto or carnivore diet. I have an appointment with my psychiatrist in a few weeks. I want to work this into our session and have her...

Familiar with it. Dairy is strangely problematic. Aside from gastro problems, my right nostril starts bleeding. Yes, just my right nostril. Maybe if I slowly added yogurt or kefir by the teaspoon or tablespoon I can avoid or even eliminate that.

Bel, I know you've been struggling to regain your health. I indeed see parallels in the issues we deal with. And, like you, I've got a bedroom with boxes of supplements that never helped me or helped a little, then turned around and bit me in the ass, LOL. It's possible that the H. Pylori...

Vince, I've had mental health problems since I was a child. As to diet, in 1970 or '71 was diagnosed with multiple food sensitivities. Cut out sugar, gluten, eggs, chicken, dairy, tomatoes, onions. Followed that elimination diet for about 20 years. Benefits: zero. Continued to have...

No disagreement, Vince. There are three cutting edge psychiatrists in the Boston area, all who place a major emphasis on diet; tending mostly to a keto diet. But they also use medications. I do wish that most physical and/or mental illness was resolved by diet, alone but I've yet to see it...

The microbiome has emerged as major factor in human health and function. Though I do have a long history of IBS, a comorbidity of bipolar illness, bipolar is a neuroendocrine disorder. From the brain to the gut to the immune system to the endocrine system to the autonomic nervous system...

I can't explain it. All I've observed is that my gut works fine if, minus the ester, I'm deriving at least 20 mg or more of testosterone, irrespective of injection frequency, though I was doing 100 mg E5D, then went to 70 mg twice a week. I know your total and free T are good. I've told my...

Vince, I would not have made the connection, either, if I didn't experience it. And I eat fruits, vegetables, beans and nuts. Not even high dose vitamin C or magnesium was helping. It's an odd one, even for me! I've just started back on desiccated thyroid, taking it at night, in an attempt...

There is a connection between testosterone and gut motility. J Clin Invest. 2022 Jan 18; 132(2): e150789. Published online 2022 Jan 18. doi: 10.1172/JCI150789 PMCID: PMC8759776 PMID: 34847080 Diminished androgen levels are linked to irritable bowel syndrome and cause bowel dysfunction in mice...