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  1. Nelson Vergel

    Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis

    https://www.excelmale.com/threads/testosterone-therapy-and-erythrocytosis-the-most-common-dose-limiting-effect-of-testosterone-therapy.30257/
  2. Nelson Vergel

    The Psychedelic Revolution Is Coming

    Who Will Own the ‘God Molecule’? Psychedelics devotees are racing biotech entrepreneurs to turn 5-MeO-DMT into a pharmaceutical. https://nymag.com/intelligencer/article/god-particle-5-meo-dmt-drug-pharmaceutical-market.html
  3. Nelson Vergel

    Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis

    I think increased BP after starting TRT and seeing an increased hematocrit is THE indicator that your cardiovascular system is not as "flexible" as it should be to handle either increased blood volume (edema) and/or increased viscosity due to higher red blood cell concentration. Younger guys...
  4. Nelson Vergel

    TRTManager for iOS

    Great idea! @Jason Sypolt created a site 9 years ago but we failed to maintain it. https://www.excelmale.com/threads/new-testosterone-replacement-analyzer-app.29267/ https://www.discountedlabs.com/blog/new-trt-analyzer-app-just-launched
  5. Nelson Vergel

    Is this real?

    From Perplexity: What Russia Has Actually Announced · Alexander Gintsburg, head of Moscow’s Gamaleya National Research Center, says the institute has built an mRNA “oncovaccine” that will be customized for each patient’s tumor with the help of artificial-intelligence algorithms[1]. ·...
  6. Nelson Vergel

    Smoking Cessation's Effects on Male Hormonal Levels

    This scientific paper investigates the effects of smoking cessation on hormonal levels in men, specifically focusing on steroid hormones like testosterone, DHEA, DHEAS, cortisol, and sex hormone-binding globulin (SHBG). The researchers aimed to determine if these hormonal levels could predict...
  7. Nelson Vergel

    Falling off a cliff in New Zealand.......Help!

    https://www.excelmale.com/threads/starting-on-trt-compound-cream-and-joining-the-forum.26590/page-2
  8. Nelson Vergel

    Falling off a cliff in New Zealand.......Help!

    https://www.excelmale.com/threads/greetings-from-new-zealand-compounded-testosterone-cream-q-a.21815/
  9. Nelson Vergel

    Falling off a cliff in New Zealand.......Help!

    https://www.excelmale.com/threads/testosterone-doctors-in-new-zealand.15983/
  10. Nelson Vergel

    Anastrozole - Enduring Side Effects 5 Years Later

    The Role of Estradiol (Estrogen) in Men's Health and Testosterone Replacement Therapy (TRT) This briefing document synthesizes information from various discussions on the Excel Male TRT Forum regarding the critical role of estradiol (estrogen) in men's health, particularly in the context of...
  11. Nelson Vergel

    Anastrozole - Enduring Side Effects 5 Years Later

    Anastrozole for men” increasingly appears in medical literature, endocrine clinics, and online forums as clinicians and patients look for ways to balance testosterone‐to‐estrogen ratios, prevent gynecomastia, optimize fertility, or fine-tune bodybuilding protocols. A close reading of...
  12. Nelson Vergel

    Methylene Blue Pros and Cons

    Methylene Blue Human‐study dosing at a glance Setting / studyRouteDoses actually givenExposure periodTypical body-weight equivalent*Key note 3-D human-skin model (Scientific Reports 2017)Topical cream/medium0.1 μM, 0.5 μM, 2.5 μM (≈ 0.00003 %–0.0008 % w/w)14 days dailyn/a0.5 μM gave the...
  13. Nelson Vergel

    Methylene Blue Pros and Cons

    DEEP DIVE: Methylene Blue as an Anti-Aging Intervention Introduction Methylene blue (MB) is a century-old synthetic dye and medication that has recently gained attention for its anti-aging potentialpmc.ncbi.nlm.nih.gov. Traditionally used for conditions like malaria and methemoglobinemia, MB is...
  14. Nelson Vergel

    High levels of antihistamine drugs can reduce fitness gains, study finds

    Really? I am going to try it. How much do you take? Thanks
  15. Nelson Vergel

    Methylene Blue Pros and Cons

    https://www.empowerpharmacy.com/compounding-pharmacy/methylene-blue-capsules/
  16. Nelson Vergel

    Methylene Blue Pros and Cons

    These scientific articles explore the anti-aging potential of Methylene Blue (MB), a traditional drug, for human health, particularly focusing on its effects on skin longevity and its broader implications as an anti-aging drug. Both sources, published on the U.S. government's National Library of...
  17. Nelson Vergel

    Medications that Can Impair Muscle Mass and Strength Gains from Resistance Training

    https://www.excelmale.com/threads/do-multi-ingredient-protein-supplements-augment-resistance-training-induced-gains-in-skeletal-muscle-mass-and-strength-a-systematic-review-and-meta.17940/
  18. Nelson Vergel

    Medications that Can Impair Muscle Mass and Strength Gains from Resistance Training

    Introduction Many common medications – both prescription and over-the-counter – can influence the muscle mass and strength gains achievable through resistance exercise. Some drugs impair or blunt muscle hypertrophy and strength development, while others enhance or exaggerate these gains. These...
  19. Nelson Vergel

    Exercise and Sexual Function- Review of Studies

    Briefing Document: The Relationship Between Physical Activity and Sexual Function in Adults Source: Excerpts from "A Systematic Review on the Relationship Between Physical Activity and Sexual Function in Adults - PMC" (Almuqahwi et al., 2023) 1. Executive Summary This systematic review...
  20. Nelson Vergel

    High levels of antihistamine drugs can reduce fitness gains, study finds

    These articles discuss how histamine-blocking drugs, often taken for allergies, can negatively impact the physiological benefits of exercise. Both sources present studies indicating that high doses of antihistamines interfere with muscle adaptation, blood flow increases, and overall fitness...
  21. Nelson Vergel

    NAD+ Injections- Pros and Cons

    You can get it by prescription at Empower Pharmacy https://www.empowerpharmacy.com/compounding-pharmacy/nad-injection/ https://www.empowerpharmacy.com/compounding-pharmacy/nad-nasal-spray/ https://www.empowerpharmacy.com/compounding-pharmacy/nad-cream/...
  22. Nelson Vergel

    Any Testosterone Propionate Compounding Pharmacies left?

    They only have this combo https://www.empowerpharmacy.com/compounding-pharmacy/testosterone-cypionate-testosterone-propionate-injection/ They said that they weren't getting enough prescriptions for propionate alone.
  23. Nelson Vergel

    Modulation of circulating free testosterone fraction by T, DHT and estradiol during TRT

    Since I seem to be "slow" in understanding this highly scientific language, I had AI transform it. Plain-English Summary 1. Why this matters o In the body, only the “free” (un-bound) portion of testosterone can actually get inside cells and do its job. o Most calculators that doctors...
  24. Nelson Vergel

    Free Testosterone targets for the best Libido

    Let me ask my developer. I think I screwed up a cache rebuild. Hopefully we can reverse. Sorry about that.
  25. Nelson Vergel

    Free Testosterone targets for the best Libido

    @madman this one? https://www.excelmale.com/threads/modulation-of-circulating-free-testosterone-fraction-by-t-dht-and-estradiol-during-trt.30832/
  26. Nelson Vergel

    Free Testosterone targets for the best Libido

    I have no idea. You remember about when you posted it?
  27. Nelson Vergel

    ExcelMale.com: The Most Comprehensive TRT Forum for Men’s Health

    ExcelMale.com is widely regarded as the ultimate online forum for testosterone replacement therapy (TRT) and men’s health discussions. Founded in 2013 by a leading men’s health advocate, this platform has grown into a vast community with tens of thousands of members, ranging from newcomers...
  28. Nelson Vergel

    Understanding the Influence of Genetic Differences on SHBG Hormone Levels in Men

    SHBG Gene Polymorphisms and Testosterone Concentrations in Men 1 source This source presents a journal article from "The Journal of Clinical Endocrinology & Metabolism," published by Oxford Academic. The article investigates the impact of genetic variations, specifically single-nucleotide...
  29. Nelson Vergel

    What it the purpose of Sex Hormone Binding Globulin (SHBG) ?

    We have discussed that your statement only applies for men not on TRT.
  30. Nelson Vergel

    Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis

    From this thread: WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT - Excel Male TRT Forum Underlying Physiological Mechanisms Testosterone Replacement Therapy (TRT) and Erythrocytosis: Exogenous testosterone stimulates red blood cell (RBC) production...
  31. Nelson Vergel

    Lipo-C - Who's using / what doses?

    https://www.excelmale.com/threads/lipo-c-injections-different-recipes-between-pharmacies.6061/
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