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How often do you use it? Melanocortin receptors can become desensitized to the libido enhancing effects in a lot of people if it is used more than 1-2 times per week. A 2-3 week break should help. Shelf life is going to depend on how the peptide was made. Some PT-141 products work for 30-45...

60. 8 clicks is one full dose and 0.05mL. The pen says 3mL in total. Sometimes I only do a half dose and can still feel it.

It is different from Natesto which is a spray and this is a gel (to me it looks like a white cream, but they say gel). it is around $60 for a pen through Defy. I love the stuff. You can take it 15 minutes before workouts or sex and you get a huge boost. Not for primary treatment because you...

Don’t do it. Prop is too unpredictable and inconsistent and you will regret it. Stick to the longer esters, and if you want a boost then consider the T nasal gel that Empower sells. 8 clicks in each nostril gives around a 800-1000ng temporary boost for a few hours within 10-15 minutes and there...

The ODT’s are interesting and I have tried several from PDE5’s to Oxytocin, and others, and they seem very effective. ODTs have to meet certain criteria such as dissolving in the mouth with no water within a specific timeframe. As long as the dalton (molecule) weight is low enough that the...

It’s worth giving Bremelanotide a try without Trimix or even a PDE5. I can’t overstate how powerful it is and how effective it is at causing an erection. **Walking** will give you an erection that would challenge any young guy just from the everyday friction of your pants. It happens even just...

Yes, I sat in on a product information session on Wednesday that reviewed Oxytocin and Bremelanotide and it was mentioned. Trimix guarantees an erection for hours. And the erection-causing effects of Bremelanotide are no joke. It would be unwise to combine the 2. You also should not use a PDE5...

It is not recommended to use Trimix with Bremelanotide (PT-141). There is a real risk of priapism.

What Nelson said, but keep in mind that androgens do affect the kidneys in various ways. have you tried magnesium? It has been reported to help with various types of cramps.

I'm not sure what you have in mind by "microdose", but there were some studies from the 70's or 80's on Oxandrolone and its effects on lipoproteins. They were using < 10mg if I remember correctly. It's a really interesting drug. I am taking Nandrolone and Oxandrolone right now and the only...

Some clinics are still open. It is definitely a risk, but it’s your personal choice and yours alone. There is an alternative to injections that was mentioned in compounded T cream. When applied to your scrotum, it can go toe to toe with injections and can even lead to better libido than...

A few points to consider: Your T is fake. No offense, but looks legit and seems reputable doesn’t make it so. It’s a risk with UGL and you lost this time. Even with low SHBG, 3x weekly would be enough to see a serum T increase. Your PRL is a bit high. Your SHBG was low before TRT. Very, very...

When it was made will depend on the type of compounding pharmacy you received it from. A 503B like Empower is an outsourcing facility and can mass produce products. Because of their size, I doubt Their products sit for very long. A 503A however has to compound the products when they receive a...

The potency of the products do not suddenly drop off a cliff after the BUD, but the loss if any is not known because the products aren't tested beyond when the BUD would be - 6 months, or 12 months, or whatever the BUD is based off of. So the BUD is simply the cutoff date of known values such as...

Those are great markers. I am not sure about in the UK, but LabCorp has an excellent NMR LipoProfile test. The name is proprietary to them but you may be able to order the same tests included in the panel if LabCorp is not available. It’s not that LDL and HDL aren’t important, but they aren’t...

Defy Medical received this notice from UPS and I wanted to be transparent with our patients and anyone else who depends on their medications being shipped to them. Fedex is mentioned by the UPS rep making the assumption that they are affected as well, but I have not seen an official notice from...

No, consults can be scheduled quickly. The delays are with shipping products anywhere.

I will first apologize to everyone inconvenienced and concerned because of delays. We have had a massive influx of calls and orders and emails. We are getting through those much faster now, but delays (or not) in shipping are partly going to depend not only on the pharmacy since they make the...

Yes, we test for DHT when a patient is on a T cream. DHT is involved in a lot of things not the least of which is libido, so I highly recommend checking it at least 1-2 times a year no matter what type of treatment one is on. It's good to get a baseline if nothing else and then see how that...

There is no way to determine that and there is no formula or guideline because it's highly individualized. The numbers and results really do vary drastically from person to person. All anyone will say is "a lot more" as some of the replies of DHT results indicate. Nothing will currently come...

Simply taking T will increase DHT. But DHT only increases significantly (and it does increase significantly) when applying a compounded T cream to the scrotum. You should NOT apply Androgel, or any alcohol-based gel to your scrotum by the way. It will burn.

Changes in hormones will cause it. It is normal. Your other symptoms though are something other than hypogonadism if your labs are in range and you feel exactly the same on different protocols. This thread is about low SHBG. Please read my other posts in it. Your SHBG is low, so you have IR and...

Your problem is not testosterone.

You probably don't need to lower your T dose to add Nandrolone. I was prescribed 50mg BIW and I divide it up into 20mg every weekday and have had zero problems with H&H which was the only concern. My last H&H results were actually lower than before I started the Nandrolone.

It was 8-10 before. 25 now. T3 (Cytomel/Liothyronine) fixed my thyroid. Nandrolone increased lean body mass which increases metabolism and helps burn fat. And Stanozolol will burn fat rather quickly. Getting proper labs to monitor and measure everything.

Both, but I was mostly feeling no positive benefit at all. I changed my diet slowly because that was easier - 6-7 months. Cut back on sugar, pasta, noodles, potatoes, breads, and I don't eat rice that often. I drink carbonated water instead of soft drinks although Nelson and I split a Coke on...

It's really an association between SHBG and IR and not bodyfat. I was not fat either, and I had perfectly normal glucose and A1c as well. Check your fasting insulin and thyroid (TSH, Free T3, Free T4, Reverse T3). You will probably be shocked. The normal range for insulin is BS just like with...

If you had low SHBG prior to taking testosterone then you have insulin resistance. It's virtually guaranteed. Fix that, and you fix the low SHBG problem which in turn makes TRT drastically more effective.

I am only able to give my personal opinion on that for what that is worth. I do have a question though - I will PM you.

Great question, but there is really no one-size-fits-all answer to it. We could be talking natural vs hypogonadal, vs someone on an existing TRT protocol, and even comparing 2 patients often is not a great comparison at all because many people need very different amounts of T and other...

The HCG and FSH problems are really separate now and apply to nearly every compounding pharmacy. There was a law passed in 2009, the BPCIA which is only now taking effect (on March 23rd). The FDA classified HCG and FSH as biologics (because they are). Biologics are derived from living tissue or...