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A lot of people do not absorb cream well (including me). My buddy and I started on cream at the same time. He achieved awesome TT and FT levels on the initial dose and I was not able to reach his levels even at 4 times his dose. Also, most cream protocols are 2xday, just fyi.

She actually said almost all her patients switched to pellets from injections. That's why she claimed they felt better on pellets. I'm not saying to go with pellets. I'm just saying I know there's one doc in my area that seems to be doing them successfully for her patients.

There is one doctor in my area that does pellets only for all her patients. She has several hundred patients and she has a wait list of roughly 2 months for new patients. I opted not to go with her (went with cream and then injections), but she claims all her patients feel better on pellets.

There is no (or very little) debate on the accuracy of TT labs. The tricky part is what method do we use to determine low FT? My pre-TRT TT was 718 (264-916) and my direct FT was 72 (52-280). But if TruT is accurate, my FT using TruT would have been 234 (52-280). So if I were using the TruT...

I've been reading this and another TRT forum for over a year now and I think some people just don't respond well to TRT. That said, there are a lot of things to try before giving up (AI, lower dose, supplements for sleep, cream vs. injections, etc.). I mean just look at all the stuff @Systemlord...

My E2 is 57.2 pg/mL (7.6-42.6) on 20mg per day - Yes, I know it's the wrong test.

My natural TT was 718, but my FT was almost bottom of the range. I had metabolic syndrome, crazy high triglycerides, crazy high cholesterol. My doc said I was on my way to type 2 diabetes and was high risk for cardiovascular disease. I was overweight and couldn't lose it even though I work out 6...

I kept getting a rash and bumps from the cream on my skin and all the treatments my doc gave me for them wouldn't resolve them. Also, I'm a poor absorber and I couldn't get my TT and FT levels as high as I (and my doc) wanted to on cream.

You might want to try your normal dose of cream in the AM and a smaller (maybe half) dose in the PM. My buddy does that so he can sleep and it works well for him. Also, another option you might want to consider is injections and cream. This might get you relatively stable TT and FT levels and...

I think that's the whole point. TruT has determined that SHBG has a much lower impact on FT than previously thought. I only started TRT because my doc said my FT numbers were really low even though my TT was 718. If I had been going off of just the TruT calculator, I probably would have never...

I only have my SHBG for the lab on 14mg ED. It was 35. SHBG only affects the TruT calculator a little. The difference betweeen 15 SHBG and 60 SHBG at 730 TT is like 3 FT. So SHBG definitely does not account for the difference in FT.

This is where I wonder how accurate the TruT calculator is. Before I started TRT my TT was 718 ng/dL and my FT was 72 pg/mL. On 14mg ED test cypionate my TT was 730 ng/dL and my FT was 202 pg/mL and my body composition was drastically different (gained muscle mass, lost fat). I did not change a...

I am on 18mg of test cypionate ED. No HCG. No AI. I don't have numbers on 18mg ED as I just lowered my dose 3 weeks ago from 20mg ED. On 20mg ED I was TT 1090 ng/dL, FT 280 pg/mL, E2 57.2 pg/mL (non-sensitive, I know wrong it's the wrong test).

So does this mean that the TruT calculator is totally inaccurate?

Actually, my doses were wrong. I started on 100mg 2xday, then 200mg 2xday, then 300mg 2xday and finally 400mg 2xday. It was 20% compounded cream in 200mg/ml Atrevis base (versabase didn't work for me). The 100mg 2xday dose cost $160 for 3 months. It didn't come in a topiclick. Medquest sent...

My labs were run in a 4-5 hour window after the first application each morning. So I'd apply like 8am, run labs noon-1pm. I felt great and had insane libido at the 150mg and 200mg 2x day doses. At the 50mg and 100mg 2x day doses my TT and FT were low-midrange like TT 500 FT 120 and I didn't...

I started at 50mg 2xday, moved up to 100mg 2xday, then 150mg 2xday and finally 200mg 2xday. It was all from Medquest in Utah. It was all to the scrotum except when the doses got high I had to apply to inner thighs cause there was so much cream. I am not a good absorber. At 200mg 2xday I was TT...

My doc starts all his patients off on 2xday cream (including me). 80% of his patients are on cream. 20% on injections. I had skin irritation issues so I had to switch to injections. On cream, I felt great and the libido was insane. Cream was very inconvenient though. The drying and not being...

I've heard some people that do 3 doses a week. I would prefer EOD as it's easier to remember when to inject. At the end of the day I don't think it matters much.

20mg EOD is actually 70mg/week. To calculate weekly dosing when on EOD just use 2 weeks and divide by 2. So for 20mg EOD, 20mg x 7 doses = 140mg / 2 weeks = 70mg/week.

I think this can help for some people and I'm happy to hear it worked for you. That said, I think the majority of the people that have sleeping issues on TRT are having them because of other physiological issues (too high a dose, low iron, thyroid problems, adrenals, neurotransmitters, etc.)...

My issue is staying asleep as well. Have you tried the extended release melatonin? My doc has me taking 10mg of Nature's Bounty extended release melatonin. It's half instant, half over several hours. I get 6-6.5 hours of sleep consistently. Sometimes I wake once but I am able to go right back to...

Have you tried magnesium glycinate and melatonin for the sleep issues?

Sorry to hear your latest attempt at TRT did not work out well. You've definitely had a rough go of it for a long time. This makes no sense at all. Curing diabetes is an often touted benefit of TRT. Honestly, I would consider getting a really good nutritionist. They will sort out if you have...

Hmm...if I punch in 916 ng/dL for TT(highest of range) and 30 SHBG, it returns 32.8 ng/dL. 40 SHBG gives 31.61 ng/dL. So, the reference range people that have 916 ng/dL don't have any lower than 40 SHBG?

Just curious...if you are calculating FT off of TT using the TruT calculator, why are you still using the reference range 16-31 ng/dL from the FT test that you say is wildly inaccurate?

My doc tells all his patients to inject subq in the upper legs. My legs are really lean and this caused some mild discomfort for me so I switched to the abdomen (from 2" away from belly button all the way out to love handles). I inject 1" away from last injection site and there is tons of room.

You might want to try injections along with cream. I read some people are trying that and really liking it.

My doc always had my labs drawn 4-5 hours after applying the cream.

20mg cypionate daily subq. 140mg per week.

I felt absolutely amazing on the scrotal cream. Energy and libido were off the charts for me. Plus I slept much better on the cream. Unfortunately, I was not a good absorber (applying 2g 2xday only got me to 190 FT) and it also caused unresolvable skin irritation so I had to switch to...