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It is! I just called my doc and asked for a reduction in concentration to 50mg/ml, I believe empower carries a pharma grade for this, probably what you showed me in the pic The maximum I got from the Pregnenolone caps or scrotal Progesterone was .5 or .7, I would look at least to get to...

according to this paper, men produce anywhere from 0.416 to 0.75 mg/day of Progesterone "The production rate of endogenous progesterone and hence the natural progesterone levels inplasma show a large variation, depending on the species, sex, age and physiological status. Inhumans, the...

thanks. My doc just approved a 100mg/ml, I think 50mg/ml may help better with dosing. He put me down to start at 2/3mg daily SQ, probably a bit too much to start, however injecting testosterone SQ in the past resulted in much less absorption for me, maybe that is why he wants me to start at...

I think it comes to the delivery method used. Anything that goes to the first pass in the liver or that is applied to the skin could totally have a non physiologic effect, so more like a drug effect. I believe the injection route of administration for Progesterone probably the closet to...

Hi guys, I mentioned in the past that using Pregnenolone cream enhanced my color perception, especially the flashing colors which I would describe almost disturbing. However, when I would generally stop the cream the side effect would disappear within few days. I haven’t used the cream now for...

@Gman86 what was the concentration and base of the injectable Progest? How much did you inject?

Hi Guys, Progest-E was formulated by Ray Peat, it is combined with Vitamin E, and should by pass the first pass in the liver. I'm wondering if anyone has tried this before. To my knowledge this is the only oral Progesterone product that skip that first pass in the liver Dr. Peat's Progest E...

Since we are talking about Progesterone here, has anyone tried a Product called Progest E? I have been looking into Ray Peat’s work, and he mentioned about this product which is Progesterone mixed with some vitamin E, which according to him would by pass the first pass in the liver, therefore...

@Gman86 we chatted before about Iodine, I’m currently using 250mcg only, I believe if someone wanted to supplement with it, 250mcg to 1mg max of Potassium Iodide may be k

Your low ferritin stands out here. Blood donations?

Thyroid hormone helps to convert cholesterol into Pregnenolone, maybe that helped to some extent, did you cholesterol decreased as well?

Are you still using HCG?

I used to, but considering it again since for some reason I have been starting having some trouble with the Pregnenolone for the past year or so, not sure why.

You not longer use Prog? What do you do now to raise Prog levels?

We will see. I’m going to try a new mask see if it improves my SpO2 and RBC

I believe they have resolved the charging issue, 7min charge now can last for 8hr, or something like that I was told at the Apple Store.

@Blackhawk I bought a Sp02 monitor on Amazon and I’m generally have anything from 2 to about 5 drops per night to 91% oxygen saturation. Not concerning as far as sleep apnea I believe, but possibly just enough for the TRT to give more chance to the body to make more RBC. My HR doesn’t even...

What do you think about an Apple Watch? I’m thinking to get a new one, it does also record Sp02, HR and body temp. I believe the upcoming one may have a blood glucose monitor as well

an update here, the 100IU day are still working for test atrophy, calm feeling and some energy I believe. The start at 150IU was really crazy, this is way better. I may try 125IU later on

thanks, this is good info. You just convinced me to buy a SPO2 sleep meter. It makes me think the new CPAP could have made things worse then for me as well, the SPO2 meter will tell. I really started to see the RBC going up since the new machine

This is interesting, thanks for posting. I really would have thought the more Test the more the RBC goes up. We can see how above 50mg things get a little nastier, just where we may get into a supraphysiological dosing. One thing I want to point out, I heard this from Nelson the first-time...

I don't, I use an apple watch though. Although mine doesn't show the oxygen level, I can see the HR which never rise more than about 60, then there is a respiration rate report, which is normal. Years ago when I was diagnosed with a mild sleep apnea, I believe my HR would rise at about 80/90...

When I donated I was at 40mg less of my dose, my body should have replaced red blood cell at a lesser degree already. Plus the additional 14mg dose reduction 3 months ago. We will see, Luckly I have enough ferritin and can donate some blood

The reason I started to lower my dose was indeed to get closer to physiologic dosing of Test CYP My levels were never too high though, even at 140mg on EOD protocol TT at 700 with FT at 26 ng/dl (equilibrium ultrafiltration). 126mg weekly on EOD, TT at 500 and unfortunately, I didn't get back...

I don’t even think I need it anymore either. I was diagnosed with a mild sleep apnea during the 2017, I used the macchine for a little bit that year and maybe during the 2018, but couldn’t get used to it, then I didn’t touch it till 2 years ago when GF told me I was snoring. I was hoping it...

Last year my RBC started to go up for no apparent reason with no changes in TRT dose, I have seen it in December of 2022 at 5.9 with HGB at 18.7 At the beginning of this year I started to lower my Test dose from 180 to 140mg weekly. Again 3 months ago I went from 140 to 126mg weekly, along with...

I have been trying the 100IU daily from last week, and they are definitely reversing testicular atrophy for me, better orgasm and overall better enjoyment with sex, along with more energy and feeling more calm despite progesterone level was unchanged. It must be the HCG doing something at those...

I had to go down to 100IU daily, 150 was just too much to start with

a 25% increase in cortisol after a 10.000IU IM injection of HCG. not our typical dosing

it started to affect my sleep, more difficult to fall asleep, waking up 2/3 times per night and having really vivid dreams. Getting up in the am with the feeling of not sleeping but still with energy. Then, I believe it gave me some sort of anxiety that was probably almost similar to being...

how was you experience with 100Iu daily? did resolve all of your side effects? were you using Pharma HCG or compounded?