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Good evening I apologize that you had no success in getting through at Defy You are welcome to PM me your info as I would like to look into what happened. Defy uses an answering service to take messages outside of operating hours, or when all employees are on the phone. Messages from the...

Study: Latanaprost may be a viable hair loss medication A double-blind scientific study published in the May 2012 issue of the Journal of the American Academy of Dermatology has found that latanoprost, a drug that mimics naturally-derived compound molecules called prostaglandins, significantly...

Resveratrol, a substance found in the skin of red grapes and in other fruits, has attracted quite a bit of attention in recent years for its potential disease-prevention and anti-aging capabilities. Resveratrol is a type of natural phenol produced naturally by several plants when under attack by...

Just saw your question on transdermals If a transdermal cream (Lipoderm, HRT, etc) when it starts to turn yellow you want to discard. Gels will become "chunky" or discolored. It does not take long for this to happen when gels/creams are exposed to air. If properly stored you should get 3...

Great questions Pacman I know I have posted some info before on BUD but could not locate it. The BUD has everything to do with recent enforcement (and updates) in USP797 which governs all sterile injectables. In the recent past, a compounding pharmacy could rely on previous established BUD as...

Great advice from all! I wanted to add, never make conclusions from just one test result. Follow up with another blood test panel and then check annually thereafter (or more frequent if deemed necessary) A single blood analysis may not provide an accurate picture. I know of no exact science...

I am not a doctor but have some understanding of how sermorelin works. First, IGF-1 should not be the focus to assess response to ghrh like Sermorelin. IGF-1 by itself can provide a good initial evaluation to determine if one might benefit from sermorelin or any GH boosting therapy. If you...

Regarding the bad reaction some get with Sermorelin, this is from the medication insert (Geref): ADVERSE REACTIONS The following adverse reaction, in decreasing order of frequency, have beenreported following sermorelin administration Transient warmth and/or flushingof the face...

Here is a link with printable directions for mixing and administering Sermorelin. The directions are for the 15mg Sermorelin vial but can be adjusted for different strengths...

Don't be nervous, testosterone being on back order has been a rare occurrence! Its always good to understand the process because if one pharmacy tells you something is on "back order" it does not mean that you cannot obtain it at the pharmacy down the road. As we always say, knowledge is power!

One of the most frustrating things for a guy on testosterone replacement therapy is when the pharmacy cannot refill medication due to it being on "back order". Back-order can of course mean many things, and since pharmacies sometimes fail to explain to the patient what is happening I thought I...

Testosterone needs estrogen's help to inhibit depression In popular culture, the phrase “battle of the sexes” seems to pit the male hormone (testosterone) against the female (estrogen). Now a Florida State University College of Medicine researcher has documented a way in which the two hormones...

Thank you for sharing Julius It appears that by the medications you currently take that you may be already prone to having anxiety and panic attacks? One of the medications, clonazepam, is a benzodiazepine which over time can cause rebound or "break through" anxiety due to its affinity to the...

Julius- It would be helpful to have more information as anxiety is complex and can occur for different reasons. Important information would be how long have you been on TRT? Do you currently take any medication for depression, anxiety, or sleep? Do you drink alcohol, if so how often? Has...

Interesting question regarding the difference in specifically anabolism between the two methods. It should not change because remember anabolism from T is relative to maintaining T levels. If both once per week and twice per week injections keep your T within range, than you will still be...

Magnus- You can always blood test electrolytes and magnesium, they should be very cheap and available on sites like discountedlabs.com. Usually when presented with muscle cramping dehydration is the first suspect (as it was for you too). Since you seem to be staying hydrated and are...

As an addendum, it appears that splitting your total cypionate/enanthate dosage into more frequent injections throughout the week may be the best overall protocol to maintain good levels with minimal side effects. This also can eliminate the "up and down" curve from once weekly injection, and...

Like Chris said there would be no benefit to alternating esters since in the end you are simply taking testosterone, and alternating esters will only make it more difficult for you to stabilize your testosterone.There is no such thing as receptor sites closing or becoming tolerant to...

You mentioned the possibility of children. There is lots of evidence showing that the use of HCG during TRT can help maintain fertility and testicular function. In some cases where the patient's baseline level of spermogenesis and testosterone were low, it is possible that fertility may...

Thank you for posting rogart. It can be frustrating when dealing with ED and any length of time suffering from these symptoms is too long. Congrats on starting treatment with Dr Crisler. I think you will notice a significant difference on injections versus the topical testosterone. You...

L-Glutamine L-Glutamine- Glutamine is the most abundant amino acid in the bloodstream. It is most notable for its healing properties to the gastrointestinal tract and is helpful with ulcers, IBS, and gluten sensitivities.* Elevated cortisol levels from trauma (wounds, burns, surgeries) can...

There are some conditions that can cause eye lashes to shed faster than they can grow back. Some of these conditions might be temporary, such as stress or thyroid disorder that has not been treated. Or maybe you or someone you know just wants longer and thicker eyelashes. There is a...

Responses of different doses of testosterone injections on muscle and strength https://www.excelmale.com/forum/showthread.php?2125-Responses-of-different-doses-of-testosterone-injections-on-body-composition-strength-etc&highlight=dose+dependent+relationship+young+men

Sarcopenia is defined as the loss of muscle, fat free mass, and loss of strength experienced by men and women as they age. This is usually coupled with an increase in body fat. This change in our body resulting partly from a decline in testosterone and GH levels results in an increased risk...

First and foremost I appreciate the testimony of those who are under Defy's care on this thread. I hope to continue a high standard of service for each of you. This is also a difficult thread for me personally because of my respect and friendship with the gentlemen at lowtestosterone.com. I...

Blue- It sounds like a troche, usually they flavor them with mint or watermelon to hide the nasty taste of the testosterone itself. Even if it is not a troche, any oral form of testosterone is not the best form to take and will not metabolize sufficiently. I would request weekly injections...

Vince provided a good link about which leads to a thread discussing using HCG to preserve fertility and testicle size while on TRT

If a man is taking any form of supplemental testosterone (TRT), then his pituitary will go through a process called negative feedback resulting in the shutting down of LH. As most know, LH is a gonadotropin which is released from the pituitary with the mission to stimulate testosterone...

Testosterone is often inaccurately defined as a hormone that is important for men only. Studies and practical obervation has shown that testosterone is a very important hormone for women too. Women experience a rapid decline in sex hormones such as estradiol and testosterone while aging...

For anyone living with HIV who needs assistance obtaining Nandrolone and other quality of life treatments, check out our patient-assistance program. http://defyhiv.com

It is unfortunate that the stigma and mythology surround marijuana has delayed its acceptance as a good medicine. Cannabis is neuroprotective, anti-inflammatory, and has all kinds of positive benefits with very low risk. In fact, the risk is associated with smoking cannabis, but there are...