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No, IMO it's always good to get a baseline assessment on everything, including E2, which make sure you get the "sensitive" or ultra-sensitive assay. Also, cover the gamut on thyroid with TSH, Free T4, Free T3, Reverse T3 and antibodies (TPO and TgAb).

Welcome to the EM community! Glad you joined!

I have just been browsing a bit on your thread .. Maybe I don't know all the specifics on why you switched it up, but at a glance, I would just say go back to what you were doing before if it was working for you. If something is working just stay with it. At the same time, someone mentioned...

Something is amiss ... Dr. Saya is quite versed with the needed steps to access and diagnose thyroid disorders. Something is off if a PA at Defy is banging the "TSH Only" drum. Hopefully Dr. Saya (or other Defy Management) will chime in. When I talk with Defy, everything is on the table .. TSH...

It's a matter of factoring the entire picture, then making the assessment. The "entire" picture will factor how TSH relates with not only FT4 and FT3, but RT3, antibodies, and impacting variables like iron & ferritin, cortisol, electrolytes, D3, etc. Sometimes the elevated TSH variable falls...

OK, so you crashed your E2, it's trying to rebound, then it's not even back up out of single digits and you start taking more AI?? The body is designed for homeostasis! Stay on your TRT regiment, maybe look at adding some micronized DHEA at night to also help with some of the downstream...

Thanks for joining EM!! We are glad you're here!! Small towns, big towns, you will find Anytown, USA tends to have plenty of GP's that are not really in-tune with how to properly treat hormonal deficiencies. Plenty of members here also go through Defy and Prime Body. Possibly, you might want...

Welcome to EM! Glad you joined!!

Great, keep us posted...

No, IMO I would refrain from NDT or any thyroid meds. The goal with taking NDT would be to get T4 and T3 up, with an emphasis of elevating T3 and making it active in the cells. There sits the problem, your FT3 is already at 83%. If you're having "Hypo" like issues, then more than likely your T3...

I personally don't see a problem with the ferritin, low 100's is usually ideal for men IMO. Iron serum should also be looked at, aiming 130-150 could be ideal. The area that concerns me (at a glance) is your FT3 compared to FT4 FT3 is at 83% of reference range FT4 is at 15% of reference range...

Excellent information from VC!!

Very interesting!! Thanks for taking the time to keep a log on this. Between this and Vince's posts, I'm getting tuned into this real quick. Ordering today!

Wrench, you could probably get Dr. Saya to give you a little feedback on the supplements prior to your consultation. Maybe send a message or call. He will post on the forum from time to time as well, it just depends on his schedule. If it were me, hypothetically speaking, I would start taking...

Thread is closed ...

Like Systemlord indicated, thyroid medication can be counterproductive if other variables are not sorted out. HC therapy is great, glad to hear it, but if it's a work in progress and your cortisol levels are still sub adequate, then the T3-FT3 is going to be struggling to reach the cells...

Exactly, I'm with you Jay, let's get those answers and ideas, but you will lose the continuity of your momentum with having two threads. Your audience will lose focus if you're trying to manage the conversations with two threads. Again, your other thread is going well, good audience, keep the...

?? We have 17 responses going on a good thread with you, it's getting lots of views and attention from key members, virtually 95% the exact same subject, and you just started a new thread?? Pick which one you want?

Exactly Ratbag ^^ High RT3 is due to an underlying issue, it's a natural process to converse energy and resources when something isn't right. As Ratbag mentioned, adding Cytomel T3 doesn't resolve the RT3 issue. It's not like you can override RT3 and it will just start to diminish and fixed. In...

Just curious, how long did you wait after your last cycle to do a PCT?

Agree ... small price to pay to start getting back on course with a real life. I remember spending thousands a year on junk and things that were counterproductive. It's a matter of priorities and what the goals are in 10, 20 and 30 years beyond now. In my case, HRT and lifestyle changes in...

Excellent posts from Rat and Orrin. This forum is not only at the TOP tier of any TRT /Mens wellness forum out there, but in my opinion it has quickly become one of the TOP sites for thyroid discussion. There are some seriously smart members here with great information that is related to all the...

My eyes just started glazing about halfway through that post..

Yes ^^^^ the correlation exist!

Is your NDT brand, Armour? There has been a lot of scuttle going on since Activas acquired the company in 2014. Possibly switching it up with another brand or pharmacy compound can be the ticket ... 1.5 grains as noted in your edit, indeed might not be enough for your optimal wellness desire...

Doesn't sound good, but glad you got the MRI. I suspect you will also have some thyroid imbalances, and it would be good to see your CBC's and a metabolic profile, plus E2 sensitive, D3, iron/ferritin. Let us know

Wrench, as I had mentioned in Post 49, something "could" be triggering the unusual sub-reference hormone values, and indeed it is. Your TPO is flagged, you need to talk to Defy about autoimmune/hashis. Anti TPO is an autoimmune disorder that targets the enzymes in the thyroid. On a semi-good...

I didn't see Iron serum, but ferritin is way too low, T3 isn't going to transport to the cells, at least not in any optimal fashion. In my previous posts, it was noted about which labs are Needed: FT3, FT4, RT3 & Antibodies, and I also noted to ditch any of these useless uptake and index labs...

His FT3 is actually at 62.5% of reference range ... IMO, somewhere between 50%-80% is the place to aim for when "knowing" your FT3 is active (not pooling), thus dialing in the desired serum level based on how the patient feels. No RT3 ... Even FT4 would help to see if FT4/FT3 serum levels are...

Well, that's thing, it does put hypogonadism into play and on the table. My GP is also female, she is razor sharp in all sorts of areas, including cardiovascular, genetics, hematology, pathology, etc..., however, by her own admission she isn't all that up to speed with mens endocrine treatment...

Awesome, she treats the numbers and not the patient. She won't change, so if you want to pursue your wellness you will need to call a specialist, maybe one of the suggestions noted above?