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Thanks for your input Madman. Not sure what to think about that. I'm trying to find resources to help me understand how frequency of injection influences estradiol. I'm sure that has been discussed on this forum but I can seem to find that info.

Had my initial consult with defy this week. Mike is recommending 200mg per week (broken into 3 doses per week) and an AI as needed. Although my estradiol is ok, he thinks it may spike with TRT. Breaking the injections up to 3x per week may help reduce this. I do not want to take an AI but my...

And why is igf-1 being tested? tried looking that up and couldn't find an answer.

I started the intake process with defy and just got back the labs they needed in addition to the ones above. I will be scheduling my initial consult soon and would like some thoughts and feedback. I want to get a sense of what this means before meeting with them. Any insight from these labs...

Thank you guys for the input. I don't think I'm going to address TRT with my doctor but I am exploring all my options and really at the beginning of the TRT journey. I had been hoping the last few years that maybe this was caused by stress, poor nutrition, etc. But that does not seem to be the...

So if primary, then a sleep study is inconsequential, correct? no amount of sleep is going to fix primary hypogonadism?

I would like some perspective on my labs as I try to make some decisions. I recently got some labs back which once again showed some low-T and wonky thyroid. I have had these wonky labs for at least 7 years with little to no treatment (some T4 for a while). My pcp is open to TRT but wants me...