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Thoughts? I know this is n=1, but it is interesting that they had success treating low-T/infertility with a drug that is generally considered a non-starter (instead opting for pulsatile GnRH). Buserelin is in the same class as Triptorelin, which is much more widely available from peptide...

https://www.fertstert.org/article/S0015-0282(09)01228-X/fulltext Objective To report a patient with hypogonadotropic hypogonadism of hypothalamic origin successfully treated with nasal administration of a low-dose gonadotropin-releasing hormone (GnRH) analogue. Design Case report. Setting A...