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  1. W

    A pill that could outsell Viagra: New testosterone Rx drug

    Read over that post and yeah I’m past the point of reading into numbers to determine where I should be. Getting on trt just disconnects stuff in my brain. Shuts down any urge for sex, memory becomes hit or miss. I do get better with weight loss & depression gets better. The shutting down...
  2. W

    A pill that could outsell Viagra: New testosterone Rx drug

    I see, well I guess just first thought for me is the only thing this would offer is just easier use for intake of the testosterone from injections & those who have absorption issues via creams. Back to the grind of tweaking the trt protocol.
  3. W

    A pill that could outsell Viagra: New testosterone Rx drug

    Ah ok, I was referring to Kyzatrex, the one that releases this month. Bummer thought, this might be something different that would be a way of increasing testosterone without shutting down natural production and the host of problems that come along with that.
  4. W

    A pill that could outsell Viagra: New testosterone Rx drug

    Tried to edit my previous post but said 30 minutes had past and wouldn’t let me, adding it here. Any clue if the method of how this drugs works is by signaling to the testes to make more testosterone or does the pill itself just basically elevate the testosterone levels without going through...
  5. W

    A pill that could outsell Viagra: New testosterone Rx drug

    I’m usually not one to jump on newly released medications until I see how others have faired on it, however after 3 years of no progress with the regular trt methods, I’m strongly considering this. Price doesn’t look to bad considering that labwork and doctors visits are included with the...
  6. W

    Issues Day After Taking Pregnelone

    Is it possible to have withdrawal effects from pregnelone? Every since I’ve stopped taking it I hit a wall in terms of energy around 1-2 pm & no amount of caffeine can pull me out. I can’t remember the last time I’ve been this tired. Actually had to leave work early one day this week because...
  7. W

    Could the ratio of progesterone to estradiol affect water retention in men on TRT?

    I’ve done a lot of reading on that forum as well in regards to pregnelone and progesterone. The progesterone I take is otc and applied to the scrotum. I noticed very quickly after taking 1 click (which says 20mg) a libido boost then goes down hill quick. Hands get tight and low e2 type of...
  8. W

    Issues Day After Taking Pregnelone

    Almost like clockwork I wake up 2 -3 hours after going to sleep I wake up scavenging for carbs. So even though it helps with getting to sleep, ending up feeling less rested bc of waking up. Plus the downside of gaining weight. Bailing on it, if I could see any difference then I might consider...
  9. W

    Issues Day After Taking Pregnelone

    I have some progesterone cream I tried about 6 months ago. At the time I was just attempting to backfill hormones to see what might help. Remembered it made me feel better at first then worse so maybe by applying it daily over the next couple of days. I guess similar to how the pregnelone did...
  10. W

    Issues Day After Taking Pregnelone

    I’ve actually been reading a lot of posts on that forum in regards to pregnelone these past few days. Some good insight. I always thought pregnelone could cause elevated e2 issues but it can actually be the quite opposite according to what I’ve read there it can act as an aromatize inhibitor...
  11. W

    Issues Day After Taking Pregnelone

    After three days taking it in a row now I haven’t noticed the usual issues that continued to persist the previous times I’ve tried it. The only noticeable difference this time is that I’m also on hcg while taking it. Even though the negative portions haven’t continued like before I still...
  12. W

    Issues Day After Taking Pregnelone

    You summarized up my questions in this perfectly, especially with someone battles with depression. The dosage amount is something that confused me as well (I know dosages depend on the person) but if I’m taking 5mg and getting these side effects, I can only imagine how bad 1000mg or some of...
  13. W

    Issues Day After Taking Pregnelone

    Interesting. Any idea how long it took before it cleared up? Because it builds up for me like the issues from day 1 is bad, day 2 worse and so on. If it took 2 weeks for it to feel better I would be a train wreck mentally by the end of the first week. Also do you feel adding the pregnelone was...
  14. W

    Issues Day After Taking Pregnelone

    Tried experimenting to see how pregnelone would make me feel for it to see if it could help with brain fog & libido issues on trt. Taking 5mg sublingual usually at night I feel pretty good that night. Relaxes me and get a good nights sleep (better than usual). After about 12 hours I either...
  15. W

    Things that reduce hcg effectiveness.

    Are their certain things like different medications or anything for that matter that can mess with the absorption or how effective hcg can be? For example I know not keeping it in the refrigerator causes it to lose potency. When I first started trt a few years back I remember taking from...
  16. W

    Twice Weekly HCG Timing with TRT

    I’m currently messing around with this. Twice weekly test injections Monday morning and Thursday night. Testosterone peaks around 24 hours after injection and I’ve heard hcg does the same (have also read the hcg peaks around 48-72 hour mark). So what I’ve been trying is doing the hcg...
  17. W

    Advice needed: HCG side effects

    Gotcha, yeah I can feel the increased e2 from my hcg shots. Started at 400 iu twice per week but had to cut that out quick. Dropped it to 250 iu twice a week but still feeling the elevated estrogen. Really don’t want to go back to doing a daily shot but that might be the best option for me.
  18. W

    Libido: hCG vs higher T / E2

    Very well could be & I do believe variation in hormones is needed for some men to get strong libido. I’ve went down that path went adding variations with daily creams and different stuff in general. Never landed with anything positive. If I could just get some mental flow going, some...
  19. W

    Libido: hCG vs higher T / E2

    I know that I’m mentally flat on trt. Like, no mental motivation from adderall l, no excitement at all. Added hcg to fix this bc it sounds the neruo pathways not flowing. I’m just curious how long it can take for a libido boost to come along from hcg. After being shutdown a year. I’m not...
  20. W

    Advice needed: HCG side effects

    “For some men, the mental effects are energizing and positive, while others experience anxiety, agitation, and overall poorer mood.” Any idea if the anxiety/agitation is directly related to e2 being raised or if it’s just the side effect of hcg. Also, if the later, would the side effects go...
  21. W

    Not enough cholesterol for hormone pathway?

    Yeah, I’ve been back and forth with noticing it over the years. Only way I could tell the difference between low/high e2. Is being emotional on high e2. I’m on an extremely low dose right now 30mg per month. Adding in 1 variable and then waiting 6-8 weeks if possible to gauge how I feel. Right...
  22. W

    Not enough cholesterol for hormone pathway?

    Very low dose of Primobolan to help control e2.
  23. W

    Not enough cholesterol for hormone pathway?

    Not on any statins. Total cholesterol 155 (100-199 range) HDL 27 (>39 range) VLDL 16 (5-40 range) LDL 117 (0-99 range) Not sure if I’m low enough to where it would be noticeable. Was sort of curious in general.
  24. W

    Not enough cholesterol for hormone pathway?

    Curious of something. If you’re taking hcg to help keep those hormone pathways flowing from LH but your hdl cholesterol is low. Does this reduce how effective in turn the hcg is having results for you mentally?
  25. W

    Where to purchase Pregnyl?

    Defy should of told you they would send it to optum pharmacy and they could fill it for you for $120. They give you the option of optum or a local pharmacy.
  26. W

    Swapping To 1 Injection Per Week.

    You’re correct. I definitely typed that up wrong. Brain fog has been horrid for me today. Thanks for the pointing that out.
  27. W

    Swapping To 1 Injection Per Week.

    Interesting, bc usually you hear higher shbg folks would benefit from more frequent injections since your system is going through that testosterone quicker.
  28. W

    Swapping To 1 Injection Per Week.

    About to find out here in a few weeks. It will be my first time using Pregnyl vs compounded. Yeah, I’ve definitely felt worse on trt rather than I do now. But I’m not gonna stick with this routine forever. Just not gonna pay for medication to make me feel lesser than what I was without it...
  29. W

    Swapping To 1 Injection Per Week.

    Interesting, didn’t realize there was a type of hcg that wasn’t ideal for trt. Just thought there was the brand names then the compounded versions. When you say you feel better like what changed between the two? Notice a difference in libido or brain fog being lifted?
  30. W

    Swapping To 1 Injection Per Week.

    I believe you are right. I feel like I’m so close yet so far. Numbers look great but not having the benefit of them is hard to deal with, especially after 3 years of searching. I did that recently with trying to swap to subq only even though my numbers came back perfect on IM before that and...
  31. W

    Swapping To 1 Injection Per Week.

    Yeah, honestly I believe I was grasping for another approach that probably won’t work. However this did get me thinking. Gonna go ahead and delete this thread. Edit: Jk, can’t find a delete post option.
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