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Vince are you currently taking thyroid hormone?

Thanks Vince! I wanted to let the T3 clear out and see where I am to know if I really need full Thyroid replacement rather than just some short-term T3 dosing to reduce rT3. I am a bit intimidated by the broad range of protocols/experiences from people on thyroid hormone replacement to be...

Yea Vince its meant to be micro "μ" but keyboard only has a "u"

Hello everyone, I'm hoping someone can give some insight to this situation. I have many hypothyroid symptoms but my bloodwork is typically in range. I have taken some low dose T3 to bring down the rT3. This provided some symptom relief initially but then changed to anxiety and a wired feeling so...

I asked the Pharmacist the same question about higher strength ones to cut in half/quarters. That is because I've heard about some Pharma strategies where they charge the same per pill for a low-dose as they do for the high dose and then (in the case of Viagra and Cialis) make the pill difficult...

I just checked on 5mg daily Cialis from the pharmacy I use (who are likely not the least expensive out there) and apparently a 30 day supply is $144 CDN. Not super cheap but considerably lower than I expected. Doesn’t help with your script timing but thought you may be interested in the actual...

I have been taking Metformin for many months and it has done nothing to increase my very low SHBG.

Very good... but to be fair that was not one of the reasons I sought out TRT. Prior to starting I had no issues (that I knew of) with libido but in fact it must have waned slowly over time because it did improve significantly on TRT. It's the best on daily protocol for me!

I have very low SHBG (15.8 Range: 19.0 - 76.0 nmol/L). I can't say I had "little/no success" on less frequent injections but I settled on daily about a year ago and it has been the best I've felt since starting TRT over 6 years ago. When on less frequent injections I typically had to donate...

I am also in Canada and interested to see what you find out.

From everything I have read there is still a lot of debate on Metformin's mechanisms of actions, with many experts admitting they don't fully understand the way it works. This excerpt from fda.gov shows some of the ways it works, and in fact lists reduced glucose absorption as one of the...

I also use Now Ultra Omega-3. Highest EPA/DHA per capsule I have found and well priced. It is enteric coated so no fish taste after taking them and may help with stomach upset?

I just bought a book for my wife that may be of interest (I have not read it) seems to speak a lot to the true risks of HRT. I believe it also discusses the WHI study that scared everyone because of the negative results, but which failed to illustrate that it was not Hormone Replacement but...

FYI, I am no longer taking GSE but have maintained daily injections. My HCT has remained stable to date at around 49. I should not have changed two variables at the same time but was switching to ED because of very low SHBG and adding GSE to try and lower HCT. Did not think through the possible...

Agreed. It looks like others have found this as well but it seems that I react quickly and significantly to diet "stresses"? More than anything, I just wanted the OP to know that my experience was completely the opposite of what he was speculating about.

I have very low SHBG and frequently have high rT3. It appears my rT3 rises significantly anytime I eat Keto or restrict calories for a period of time.

Phase 2 Results for Madrigal’s MGL-3196 in Non-Alcoholic Steatohepatitis (NASH) Presented during Presidential Plenary Clinical Session of The Liver Meeting® 2018

Personally.... I would start at 100 mg x 1/week and go up (or down) from there IF necessary. Also your SHBG may be good now but a "mini-blast" could well lower it as many have seen from using higher levels of Test.

I do not travel with HCG anymore. It doesn't seem to make a difference for me during short (1 - 2 week) breaks from it.

I love this discussion and appreciate the varying perspectives. The one thing that, although touched on, is largely missing here is our main mantra of "treat the symptoms, not the numbers". Now I understand we use the numbers as a gage of where we feel the best and to help guide ideas on what to...

As said above.... check thyroid. To have made the progress you've made with your weight loss (Kudos BTW) the caloric restriction that must have been necessary to accomplish this, especially for an extended period of time, could have affected your thyroid hormones. My reverse T3 goes high when I...

Does not appear to be discontinued? https://www.merckvaccines.com/INTERSHOP/static/WFS/Merck-MerckVaccines-Site/-/Merck-MerckVaccines-merckvaccines-responsive/-/Order-Vaccines/Documents/files/Backorder_Report.pdf I was told quite a while go it was discontinued as well..... but I think that means...

Single Dose T3 Administration: Kinetics and Effects on Biochemical and Physiologic Parameters

Blashy, I know it has been mentioned in several posts, but in case you haven't seen them, The sensitive E2 test is now available in Canada from Dynacare

All good points! I have not checked basal temperature but should have. The fatigue has abated since I started on T3 and I still feel good and I am sleeping much better. My goal is to taper off (5 mcg then 0) to see if i remain in a good place without rT3 pooling. If rT3 rises again and/or the...

I have always heard that ANY amount of exogenous Thyroid hormone would shut down your endo production however I have been able to take 10 mcg of Cytomel daily for several months while maintaining a TSH of 1.05, and T4 in a good range so it at least appears I have supplemented without shutting...

VC my "belief" is that my rT3 was high due to intermittent fasting/ketogenic dieting. This is supported by several things I've read. I'm also curious if Low dose Cytomel may be a good strategy for dealing with the plateau one can experience when doing a lot of dieting? It may help to offset some...

Systemlord I understand your point and don't disagree in principle. The fact that I am feeling good without crushing my TSH has me reluctant, although not completely against, trying a larger dose. Lowering my TSH is only a concern to me because it SEEMS I am currently supplementing my endogenous...

I'm posting this for reference and information only but would welcome any insights/comments you all may have. In June of 2018 I had blood work done after visiting my TRT doctor regarding fatigue and trouble sleeping. My sex hormones turned out to still be in the same good range that I had been...

Yea when I first started looking at conversion sites a few years ago I didn't realize that these conversions are hormone specific for "nmol" or "pmol", as I believe these take into account the molecular weight of the specific hormone.

I looked at this conversion site and the result is 152 pmol/l = 4 ng/dl? Hormone Unit Conversion Calculator | Metric & Conventional | Men's Hormonal Health