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  1. M

    Trans scrotal testosterone cream application is a game changer

    What was your daily dose of Test Prop? Giving it some thought. Thanks.
  2. M

    Does transdermal DHEA lower e2?

    Yes, know this is thread is five years old, but it's topic is relevant: Topical DHEA on the scrotum and/or inner thighs to increase DHT, as well as T or free T. I don't know if I can convince my excellent urologist to prescribe Empower's 20%/200 mg. I have plenty of DHEA caps/25 mg and 100...
  3. M

    Iodine and Thyroid

    'Pooling' is the term for thyroid hormones in the blood but not being taken up by the cells. I've read that it could be due to low iron, low selenium or low cortisol. I have experimented with Lugol's and ended up crashing. I have a bottle of Magnescent, nascent ioidine, which is supposed to...
  4. M

    Libido/erectile function only in late evening

    Thank you. Perhaps, aside from the concentration of the cream I was prescribed a couple of times, I went by the standard prescribed dosing of once per day and the first time around, wasn't applying it to the scrotum or inner thighs. Also, there are men augmenting injections with T cream to...
  5. M

    only happy when estradiol is VERY low

    My wife has had a love/hate relationship with sex since I met her 30 years ago. I came to realize that she has significant unresolved emotional/sexual problems, most of the problems relating to her sexual past, which was before we met, and only two years ago did she allude to that past. Her...
  6. M

    only happy when estradiol is VERY low

    I've read a lot of good reports about the 200 mg trans scrotal cream. My doctor, who has three decades of experience, goes with 10%. Didn't do anything for me but I was applying it once a day on the scrotum. Still have several tubes of it. If I had some success with twice a day dosing, double...
  7. M

    only happy when estradiol is VERY low

    More likely cellular thyroid hormone resistance/peripheral thyroid resistance. Psychiatrists learn about the role of thyroid in mood disorders but few apply that knowledge in assessing their patients. Their's a psychiatrist in Beverly Hills, Dr. Jory Goodman, who wrote that psychiatrists forget...
  8. M

    only happy when estradiol is VERY low

    Thanks. Check on the magnesium & blue block glasses. Put them on at 6 p.m. every evening. Many abstracts about levothyroxine and bipolar by Dr. Peter Whybrow, who has been researching the thyroid/bipolar connection for at least 35 years and his co-researcher, Dr. Michael Bauer, in Germany. As...
  9. M

    only happy when estradiol is VERY low

    Been reading this thread again and saw your reply. Yup, we sound the same. Your trials and tribulations made me laugh. Why it's so simple for some guys and for guys like us, wandering the wilderness. Turned 72 yesterday. Wife turned 77. She's told me several times that she's finished with...
  10. M

    only happy when estradiol is VERY low

    Been re-reading this thread and started back on .25 anastrozole. Will take it 2X week, for starters. Regarding my bipolar & sleep issues, been experimenting with liquid levothyroxine at night. Started at 40 mcg, then 80, along with my .5 mg clonazepam. T4 does get me to sleep, though sleep...
  11. M

    Trimix Users...How Often Do You Use?

    Way to go!!! That's fantastic.
  12. M

    Trimix Users...How Often Do You Use?

    Your GF know you use Trimix? I ask b/c when I first tried a PDE-5 inhibitor and my wife found out, she was seriously upset, failing to understand that I couldn't achieve an erection as I once was able to. That was about 10 years ago. Thinking of asking my urologist about Trimix.
  13. M

    Hourly Intraday testosterone profiles in young eugonadal (healthy functional) men (1973-1983)

    If one knew nothing about Ikarias and just looked at the labs, that person(or persons) would come away with the impression of a large group of advanced aged unhealthy sample of the population...but the low stress, clean environment, physical activity, social/religious connections and nutritious...
  14. M

    Hourly Intraday testosterone profiles in young eugonadal (healthy functional) men (1973-1983)

    Thank you. Never tried goat and with my wife being a control freak vegetarian, only eat meat or chicken if someone else serves it. Eat lots of fish, though. She still agonizes about fish being caught. :( And yes, their raw honey. Their diet sounds quite healthy, even if the labs aren't good.
  15. M

    Hourly Intraday testosterone profiles in young eugonadal (healthy functional) men (1973-1983)

    Cool that you've been there! I got that impression that it was a pastoral place. Simple life and simple pleasures. Many of the residents were Communists and after WW2, when there was an insurgency by them, though they were active fighting the Nazis, they were exiled to the island. As for...
  16. M

    Hourly Intraday testosterone profiles in young eugonadal (healthy functional) men (1973-1983)

    @readalot/I read an article several years ago about the 'Blue Zones where people live well into their 90's and even 100's. The article focused on the Greek island of Ikarias. Though the residents aren't pure vegetarians, their diet, according to the article, was mostly vegetarian;beans...
  17. M

    Question for a Doctor....

    Different for me, as I've been on a Medicare Advantage PPO plan with nationwide coverage since moving to Florida. My wife(retired) has Federal BC/BS PPO. I can understand that regular health insurance can be like going to a casino, where the house has the advantage. The health insurers will...
  18. M

    Using Dopamine Supplements to Hack Motivation: the Neurobiology of Ambition

    We've all got to give ourselves an 'A' for effort. I've stated many times on here that my urologist has over three decades experience with prescribing testosterone, but I'm that patient who is a massive challenge and it's the same story with me and the psychiatrists I've seen. Nothing works and...
  19. M

    Hourly Intraday testosterone profiles in young eugonadal (healthy functional) men (1973-1983)

    You're welcome. I'm not a critic of high TT. For some men, having a high TT and free T seems to be the only way they physically/sexually function. Cellular resistance is cited as the culprit, as it is with psychiatrists prescribing high dose T3 or T4 or both for patients with intractable...
  20. M

    Using Dopamine Supplements to Hack Motivation: the Neurobiology of Ambition

    When I lived in Maryland, saw a psychiatrist who was also a researcher at National Institutes of Mental Health. In me she had a willing and eager lab rat, since there wasn't any drug I could take for my bipolar illness. She told me about LDN and she prescribed it. Took it at night as...
  21. M

    Hourly Intraday testosterone profiles in young eugonadal (healthy functional) men (1973-1983)

    I looked through all that you posted and for me, graphs and charts can be overwhelming. I understand the point to look back at androgen levels 40 to 50 years ago for a comparison. However, for me, what I think is being overlooked, is that when we were younger or just young, (I'm 72), our bodies...
  22. M

    Libido/erectile function only in late evening

    When doctors, even good ones, don't know what to do, we have to become researchers and lab rats. I'm impressed by what you've figured out. My libido starts to ramp up in the late afternoon/early evening and by 9 or 10 pm, I'm semi erect. Playing with it get its solid hard which leads me to...
  23. M

    Libido/erectile function only in late evening

    Cool. In bipolar illness it seems to be accepted that the HPA axis malfunctions. Until I relapsed 18 years ago, my erections were solid, including random daytime erections. The irony is that from 1994 until 2005 I was on Cytomel, prescribed by my psychiatrist. Damn, I was horny all the time...
  24. M

    Libido/erectile function only in late evening

    I'm self treating, currently, now up to 96 mcg T3 in the morning and 80 mcg T4 at night the latter to normalize sleep and slowly decrease Klonopin. The T3 is moderating my depression and my sleep quality has improved a bit with T4. I've been on and off T since 2013 and only in the past couple...
  25. M

    Libido/erectile function only in late evening

    If I take my testosterone at 6 a.m., I don't feel it until 10 p.m. Not a now and then thing; it's consistent. Rare nocturnal erections and no morning wood. I've tried different injection times, such as noon, 3 p.m., 6 p.m., 8 p.m. I suspect this is tied into bipolar illness and misaligned...
  26. M

    TRT Effect on 5 Alpha Reductase and Upstream Hormones- Cause of Low Mood and Anxiety?

    Where does one find a doctor like Dr. Gordon who will do the in-depth analysis of labs and symptoms/issues AND takes insurance? @Cataceous and I had a discussion about how does one restore the hormonal/neuroendocrine environment that we had when we were young. We're talking about looking for...
  27. M

    Question for a Doctor....

    My urologist, a long time specialist in TRT/BHRT, takes insurance. Before he relocated from Maryland to Florida, I consulted two highly reputable doctors. Both took insurance.
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