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Thanks Gene. I'm very lean - an urologist I saw a while ago for a different issue told me that I was very unlikely to have to worry about my estradiol as long as I stayed lean. Is this generally true? If so - it sure is a motivation to stay the course as far as exercise and diet.

Thanks Nelson. I purchased your book a while back and keep it handy at all times, and while it does state that the range should be 20-30 pg/mL I did not see any clarification as to which test was appropriate for that range. Maybe the next edition??

My last test showed my total T at 758. The E2 sensitive assay was 19 pg/mL (3-79 reference range), while the Roche ECLIA was 41.9 pg mL (7.6 - 42.6) reference range. Compared to a test performed 2 months ago, the sensitive was 14, while the Roche was 23.2 where the total T was 560. I...

I wondered - over the long-term - is it inevitable that all men will eventually need to take anastrozole? What if you are extremely lean and maintain that low amount of body fat?

Thanks Keith - definitely will show my endo. He does seem open-minded to tests that I suggest.

They did not perform any labs prior to starting TRT - they basically said - "Whoa dude - your overall is only 137" and started Androgel right away. I had no idea that my issues could be to low T - and I was such a trainwreck at that time - I just went along with their recommendations - I was...

A kind of query here - would going to injections be possibly a recommended alternative? I know everyone is different - but my understanding is that injections do not drive DHT up as much as gels do.

Thanks for the replies. First - the endo did perform tests and could not find any markers pointing to secondary, so he implied it was primary. As for applying the gel - I apply on my shoulders, down the back a little, to my upper arms. I'm also a very lean guy, with a BMI of 21 - if...

Hi - These results are after starting 4 pumps of Androgel in July 2013. My initial overall T was 137. While I feel much better now than I did before - I still have my doubts as to using Androgel over the long-term. I have an upcoming physical with a new PCP - and I plan to take Dr...