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I forgot to mention elevated estrogen also causes BPH (increases stromal proliferation). And is known to increase the risk of numerous forms of cancer.

IF your E really was too high, please keep us informed with respect to the changes as it goes back up again.

This whole topic has gone off the rails. NO ONE advises tanking estrogen. But E that is too high--for a particular individual--beings water retention, depression, sexual dysfunction, gyno, fatigue and weakness. Also, fat. This nonsense that E burns fat is simply not true. Guys with high E put...

I have seen all the above with high estrogen. Plus: DEPRESSION Lack of Libido Desire to buy shoes Subscribing to Redbook Magazine Watching Oprah

The videos came down secondary to a divorce. We are working to put them back up again.

Yes, they really are good people. It's always a pleasure to work with them. The positive energy around the office brightens everyone's day. I hasten to add you have to be REALLY good at what you do to work there. Everyone associated with the practice is. When you consider the average...

OOPS! I forgot to mention how knowledgeable--and just plain nice, and thoughtful--Jill, our RN, is. She's always got my back. Defy is the fusion of an amazingly well-run business and state-of-the-art Interventional Endocrinology.

As an aside, I currently have a patient who requires Anastrazole at 1mg per day. He is an alcoholic, and liver stress shunts androstenedione directly to estrogen, instead of testosterone. The alcohol also ramps up his aromatase enzyme, so he converts more T to E on top of that. I've had maybe 2...

In my 17 years (total) in medicine, Defy is without a doubt the best run medical practice I have seen. So if emails have gone unanswered, that really surprises me. But I do know, from my own experience, there are patients who send email after email, and will call numerous times (in the same...

That is because Dr. Saya is not there to try to sell you drugs; his mission is to improve your health and happiness.

Jill is certainly correct. Just changing hormone levels can bring on untoward--or beneficial--side effects. Like dropping a pebble in a pond, things even out. We may see some initial nipple tenderness, water retention, increased (or decreased) libido....all temporary, and just because levels are...

Sometimes when initiating GH therapy water retention results. It's basically the body shifting water between compartments. It evens out. Nelson, because your body is not used to higher carbs, the enzymes and pathways are different than for those who do. An analogy is when a person who does not...

Oh...I know....sometimes when I take that bottle of test cyp out, to give a patient a shot, it catches me "just right'. LOL Former smokers who restart will almost always say they were somewhere (used to be bars) and they smelled a cigarette, and it caught them "just right".

I disagree. Hypogonadism makes EVERYTHING more difficult. TRT also decreases inflammation, and increases pain threshold. Important parts of recovery. And congrats on your success!!!!

That is still a fraction of the cost of Growth Hormone. I saw an email from Defy last week that they have lowered the price on the Sermorelin.

In all male patients suffering osteopenia I try to leave estrogen at a higher concentration. Estrogen inhibits the osteoclast cells in the bones from removing calcium and putting it back into the blood stream. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199029/

Yup. This is huge. We move forward.

Even once LH/FSH are restored, it takes 3 months to make a sperm.

Excellent points, Jasen. It would take just a few minutes, and less than 100 bucks, for these people to prove the efficacy of oral HCG: A serum HCG test before, and then after, sublingual application of an HCG troche. ....to my knowledge, no one has been able to do that.

The nice folks at the Life Extension just ordered another 50 copies of my book "Testosterone Replacement Therapy: A Recipe for Success". LEF members can purchase the book at a discount. And you can get a FREE annual membership to the LEF (and get their AWESOME monthly magazine!) by clicking on...

I use it in my patients, and it works very well for many.

NICE to have a study on TRT administered by researchers who know what they are doing.

The lignans in flax seed act as estrogen in the body. As has been already pointed out, every-body is different. Having said that, while some men on TRT may need, for instance, an aromatase inhibitor while on TRT, while others may not; lignans are always estrogen. Whether the bother you or not...

If your LH and FSH are good, it basically doesn't matter. That is why we use Clomid.

You might try taking oral Danazol at 50mg per day, to lower your SHBG.

This is because insulin drives down SHBG. Additionally, insulin in high concentrations is toxic to the body.

Just stick the needle in the same place you did when you were doing gluteal injections.....except the needle is short, so it deposits the man oil into the fat.

That's how to do it!

That is very interesting. Just today a patient told me he is taking more than he is prescribed in order to "make up for that lost inside the syringe and needle". ....as if the syringe is not built and calibrated to deliver a nearly exact dose. Another thing I have heard, numerous times over...

It means your had an excellent response to the Clomid, and that your SHBG rose as well.

I believe it is! You might consider adding 50mg of Danazol each day to lower your SHBG.