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When you guys on gels/creams go to blood test, when do you do it? Is it like injections on your trough which would be 24 hours after your most recent application the following morning? Thanks

Backfilling Insulin Syringe Question... For those of you that are backfilling syringes and injecting testosterone daily, how do you store the syringes after backfilling them? Is it ok to lay them down flat? Is there a concern of the oil leaking out? Any other tips about how to backfill would be...

I've wondered if the higher DHT levels achieved by topicals would improve libido.

This goes out to the few and the proud that chose topical creams or gels over injections. What lead to your decision to choose creams/gels over injections? Can you be specific as to the factors such as mood, libido, blood work, energy, estrogen management, more stable blood levels that might...

Has anyone ever experienced thinning hair while taking any form of natural desiccated thyroid such as Naturethroid? I have tried it at doses of half grain to 1 grain a day, and within the first few days, I notice noticeable hair thinning in the front of my hairline. My labs show I need thyroid...

What injection sites do you rotate? Do you inject subq or IM? What size syringe do you use? Do you backfill or not? Do you use HCG? Finally, what’s your daily dose? Thanks, I’m thinking about giving daily injections a try.

For those with experience, do subq injections decrease estrogen levels? I’ve done a little research and found varying opinions on this. Thanks

Does grapefruit lower hematocrit? If so, is the whole fruit better or the juice?

Thanks for the input. I'm a little surprised that on a fairly conservative dose of 120mg per week, my HCT would jump 5-6 points in just 6 weeks. I'm also a little concerned about my large red blood cell size as indicated by the MPV/MCV levels. I've been taking a multivitamin with tons of B12 so...

I started TRT recently with Defy. My starting protocol is 40mg of testosterone and 200iu of HCG 3 times per week. I recently had my 6 week follow up labs done. The first lab I got back was the CBC. Here is what I’m concerned about: Hematocrit increased from 45.2 to 50.0 MCV increased from 99.0...

I just bought a product by Life Extension called Cognitex With Pregnenolone. I added this as an adjunct to my TRT. I have had several concussions/TBI's in my past. I thought it might be a little insurance against future brain disease. It has pregnenolone in it which has been proven to decline in...

I just finished my first full week of my new protocol set by Dr Saya and Defy. My starting protocol is 40mg of test and 200iu of HCG injected on MWF mornings for a total of 120mg of test and 600iu of HCG weekly. Everything is going fine so far except for one thing. I'm injecting subq with a 29G...

Thanks Vince

HCG reconstitution question... So today was the first time I've ever reconstituted HCG. I forgot to draw out air from the HCG powder vial before I added the water to it. It was very hard to press all of the water in the vial because of the pressure. When I drew out the mixed HCG for my first...

Thanks for the info guys!

Thanks for the reply

New Protocol Advice... I'm a new patient with Defy. Dr. Saya is my doctor. The protocol he is starting me out on is 40mg of test cyp and 200iu's of HCG injected 3 times per week for a total of 120mg of test cyp and 600iu's of HCG weekly. My SHBG was is fairly low at 24 which is why he is...

Thanks for the reply Nelson. Your life story and your continued interest in improving people's lives is truly inspiring.

My DHEA levels are always at the top end of the normal range. Is this a good indication that my pregnenolone levels are good? I'm curious if there is a positive correlation between DHEA and pregnenolone. Thanks

Has anyone ever read anything about mold exposure lowering testosterone and even accelerating the conversion of testosterone to estrogen? Thanks, I've read a little about this topic and was interested in learning more.

Has anyone noticed increased sun sensitivity while taking HCG? Have you noticed that you burn faster or easier? Thanks

I had my first initial consult with Dr Justin Saya this morning. To say I was impressed and literally blown away would be an understatement. He is by far the most knowledgeable and impressive doctor I have ever worked with concerning TRT. He is an incredible listener as well. I'm fairly young at...

I have my first initial consult with Dr Saya this coming Tuesday. For any Defy patients on the board, do you have any advice or suggestions? Looking back on your journey with Defy, would you recommend any info or questions to have ready for the appointment? Thanks so much for the info!

Anyone else ever had high MPV or MCV on follow up TRT labs?

I remember getting B12 tested a year ago. It was just over the top of the normal range.

I have been on TRT for 2 months with my GP. I am switching to Defy. These labs were the initial labs I had done for my initial consult with Dr Saya. These labs were not taken at the ideal time. My last Injection before the labs was Saturday afternoon with the labs taken the following Tuesday...

I'm getting ready to bring my lab order form from Defy to the local labcorp. I've heard of a few people being double billed from labcorp after they've already payed for them through Defy. Any tips to make sure this doesn't happen? Thanks

Thanks for the input guys. I have a local GP who is my age(36), and fairly open to whatever TRT protocol I want to run. My testosterone is covered by my insurance so it's fairly cheap. I just get the feeling that he doesn't know much about TRT other than the basics. I'm intrigued by the...

Quick Question for Current Defy Patients: On my journey of TRT, I have tried Pfizer's Depo Testosterone cypionate, Perrigo's generic test cyp, and recently test cyp from a local compounding pharmacy. I felt great on the first 2. The compounded testosterone not so much. It just felt weaker and...

I think I'm going to go to CVS. Two questions: What do you say when you walk in? Like, is there a certain type of physical you say you need? Also, how does Defy get a copy of your physical?

Question for Defy Patients: If your primary care doctor wouldn't do the physical exam required to become a new patient of Defy, who did you get to do the exam? Thanks