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Ouch...that's a big needle. I use a 1/2"/29ga insulin pin to inject into my quads EOD. First question: are you injecting into the vastus lateralis? That is the middle 1/3 of your quad towards the outside. Second question: why a 1"/25ga harpoon? Do you have high body fat? I just don't...

Let me put it into perspective for you. I'm 60 yrs old, and my pre-TRT test level was 526. I had all the classic symptoms of low testosterone. Is that 526 a normal level for me? According to the test level range at LabCorp, it's perfectly normal. Then why did I feel like crap? All of my...

Again I ask, sufficient for whom? You're making a broad, blanket statement, without regard to age or any other parameters. Ok, now you're making sense. However the OP did not post up full labs, and you made your statement solely about a test level of 516. I agree that the OP should have...

Neither do I. I was just throwing out some points to consider. Sorry if I came across as argumentative, but I found that your statement about 516 being a "decent level" rather ridiculous.

A decent level for whom? A 65 yr old man? How about a 25 yr old? 348-1197 is the range at LabCorp for total testosterone. Where does 516 sit on that scale? It sits 168 points off rock bottom of that range. Is this the kind of level that we are shooting for in TRT? Would it be considered...

Yes, I am feeling "off." Libido is low, maybe a touch of water weight. Not where I want to be. My sensitive E2 was 51.7 on my last labs in late Aug. I just started taking DIM and Calcium D-Glucarate (as per Dr. Saya's instructions) to see if we can bring it down that way. If I don't...

Mine has dropped with TRT. I'm 60 years old, and my pre TRT SHBG level was about 30. After almost a year on TRT, my latest blood tests showed my SHBG at 21. I inject EOD trying to avoid taking an AI. I also take DIM and Calcium D-Glucarate to help fight the high E2 (52, last test), but I may...

You're right. .25mg BIW is usually a good starting point for E2 management...for guys that need it. I'd really would have liked to have seen your sensitive E2 labs prior to starting the Anastrozole. The symptoms that you're describing (joint pain) sounds like your E2 is crashing, or is very...

Had a run? Not following you here. If you're on TRT, it's a life long commitment. You don't cycle on and off every couple of months. What exactly are you trying to achieve here? Again, not following you here. This makes no sense. Please don't tell me that you are under the care...

Look at it as a long term investment in your health. What's more important than that? It's money well spent.

Coastie, Your numbers look awesome! Weird that your SHBG rose into the 30's. Well...if it ain't broke, don't fix it! I've heard that test prop stings like a SOB too. No need for me.

A TSH of 4.7 would get my attention. If you haven't had blood drawn for a FULL thyroid panel (TSH, free T4, free T3, reverse T3, TPO Antibodies/TgAb), now would be the time to do it. A TSH test alone is inadequate, and because many doctors don't order the full panel, things get overlooked or...

OK, now you have peaked my curiosity. Why can't you handle two injections/week? What length and gauge needle are you using for this injection? There is no reason why you couldn't use an insulin pin (1/2"/29 or 27 ga) for these injections. If you don't have a lot of body fat, a 1/2" needle is...

I've never used anything other that grapeseed oil. Works for me. Cottonseed oil might be another option for you.

How did it become clear that your E2 was high? Did you have lab work to back this up...what symptoms? Why no HCG from the start? Jesus man...get a doctor that knows what he's doing. Defy Medical would be a great place to start. Don't just stop TRT. Your endogenous Test production has...

You're not starting up the anastrozole again, are you? I hope that was just a typo.

Your E2 is through the roof. Is this the sensitive assay? If not, it's the wrong test. At any rate, I wouldn't change your dosage...I would just inject every 3.5 days if I were you (100mg every 3.5 days). This will help lower your E2 naturally without any AI, and then you could retest your...

Geoff, First off...post up your labs, so we can see your levels. If you feel good, and everything else looks in line, then I'm a firm believer in: "If it ain't broke, don't fix it."

Loki, 200mcg seems like an awfully small dose. Personally, I think you'd be wasting your time at that dose. I've been on Sermorelin now for about 9 months (with Defy Med). My daily dose is 1000mcg right before bedtime. My last IGF-1 lab was at the top of the reference scale, so I'm hoping...

For this reason alone, your Doctor is a jerk. There is absolutely no reason for you to be harpooning yourself with such a long/fat needle to receive TRT. A 1/2"/29ga or 27ga insulin pin is all you need to inject. Switch your antiquated protocol to every 3.5 day injections. More...

Same for me.

Yikes, that is pretty low. I concur with Vince and Coastie...you should at least be pinning your Test EOD, if not daily. My latest SHBG was 21, and I'm injecting my Test EOD, with much better results than the every 3.5 day schedule.

You said that your thyroid and PSA were normal. Define normal. Post up what limited labs that you have so we can have a look. I'll bet your thyroid panel consisted of a TSH test, and that's it, right? All kinds of red flags from your primary care physician, and your Endo as well. Totally...

That would work fine. I'm a low SHBG guy, so I inject Test and HCG EOD partially for that reason. The other reasons are to help control spiking E2, and also just because I like having a day off between the Test injections, and the HCG injections. That day off makes a big difference to me...

I just re-read the Defy newsletter...guess I must have skipped over the part about Dr. C leaving Defy. I must have been staring at the pictures of Melissa and Damaris, and wondering why I never had a nurse or PA in my lifetime that looked like that! Exciting times ahead for Defy Medical...

Those are good enough reasons to start the HCG now. Like I said, 100IUs daily, or 150-200IUs EOD will be a good start for you. Remember that more frequent injections with smaller doses equals less aromatization. Well, the good news is that you don't need blood tests every week. You can get...

Drew, If you're worried about the HCG spiking your E2, just inject a smaller dose EOD, on the opposite day of your Test injections, or a real small dose daily (100IUs). I would probably start with 150-200IUs EOD...I think that's a pretty good starting point. Just curious...why are you...

Dr. C has left Defy?? What?? This is the first I've heard of this. HCG at 150IUs daily doesn't sound much like a restart protocol to me...but I could be wrong. That's the amount of HCG I'm taking with my TRT. If you're hurting (and it sounds like you are), I would call and get an...

More info please. Please clarify...you're on HCG monotherapy, is that correct? What is your protocol...you know, dosage/frequency? Are you taking anything else?

Rawx, Your SHBG and E2 levels were very similar to mine about 3 months ago. I switched to an EOD injection schedule (40mg TCyp) to see if that would naturally bring down my E2 without resorting to taking an AI. I'm drawing blood this week to check it out, and see how that worked out for me...

It's a pretty important number to know. You might want to consider getting the correct test performed at your earliest convenience. Please tell me you're not taking any AI at this time, are you?