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This is odd: the same article title was published in a different journal with different results. The article was published a month after the one referenced in the original post here and the results are worse. The 3 and 6 month total T levels are a lot lower than what is referenced in the...

Good sleep is key! I don’t think I noticed this in the early days, but I now think I can feel the ups and downs between doses. It’s possible that when you fall asleep on the couch, by then, your energy level is dropping due to your dose being 5 to 6 hours prior. Just speculation. Either way, if...

For sure. I think this is a good idea to do periodically.

Holy smokes. Have you been around here long? @Cataceous knows what he is talking about and knows exactly what he is taking. His calculations and math have educated everyone here. Countless members have benefited from his insights. And, his "real life" experience is deep. You are picking a...

I have a love/hate relationship with anastrazole. Typically, if I am on an injection protocol, I use the same dose you are using on the day of the injection. It does seem to reduce my likelihood of getting a headache, which I attribute to estrogen spikes. On the other hand, if I’m not careful, I...

Consider transdermal or Natesto (Natesto likely to be safest option).

I hear you. I am not overly excited about trying it, but it might make sense. I actually did Natesto with hCG and cream (low dose on shoulder) for a while. The combo worked well. Then, my local pharmacist, who is sort of a friend, urged me to try Xyosted. I took him up on it, which sent me on a...

I do like the ability to titrate up and down. But, it's much less of an exact science than injecting. I took a day off cream and restarted with the plan to do 100mg/day. Will see how it goes. Most injection trials have been hard for me, but I do tend to tolerate Xyosted fairly well. So, I am...

That’s a bummer. Sorry to hear it. I’ll head over to that thread and check it out. I’m in the process of trying to scale back my dose. I tend to absorb the stuff extremely well, which has posed some problems. It’s still a bit of a wild pony for me, but I’m working on it.

@FunkOdyssey, how is it going? Still on same dose and schedule?

I am a patient of Justin Saya We discussed cream at length, but not to the how-do-rub-my-nuts detail. I was a patient of John Crisler in the past (may the good man rest in peace) In fact, I believe I was one of the early observers of the mid-day crash that had many guys wanting to dose a...

@readalot, this one is for you: I am trying to figure out if the twice a day cream dosing is justified. I have heard some throw around a 24 hour half-life for cream, but I can't verify this number or where it comes from. There is some data on the scrotal cream paper we all reference, so I don't...

How the hell did I miss this thread when it first came out!? Incredible entertainment. This guy is so creepy. Absolutely narcissistic personality disorder, as astutely pointed out above. 1977 calories? Maybe the year he was born (not surprising for a narcissist)? There is nothing more annoying...

@Charliebizz, I think you mentioned this before, but have you noticed a difference between the standard base and the Atrevis hydrogel? Either subjectively or in terms of lab results? Anyone else try both that can compare?

I'm gonna wake this thread up (again). In another thread, I discuss a similar phenomenon. I have been trying to troubleshoot severe mid-day fatigue that I have been experiencing for a few weeks. My two leading candidates are sertraline and my cream protocol. I have some data that supports both...

I have a question for scrotal cream users: when you rub it in, does it eventually disappear? I have 20% from Empower and 15% from a local pharmacy. I use the topi-click to apply and rub in the cream. The Empower cream eventually disappears as you rub it in. The cream from the local pharmacy...

According to what I’ve read and my personal experience, I don’t think it will touch your DHT at all. If it does, I would expect it to be minimal.

I would love some guys who are having these issues to get their hands on some Xyosted. I am curious if the alcohol content in multi-use vial formulations contributes to the heart pounding by one mechanism or another. Xyosted is the only injectable that I tend to tolerate. That said, I think I...

Diet is critical. I altered my diet significantly to try to treat my migraines. I am not currently is diligent as I used to be, but dramatically reduced carb intake and increased fat and protein intake. Overall, much better energy and does seem to have improved headaches.

You actually are correct. It is something to consider. I’ve been on it on and off for many years. I go through periods of time when I don’t think about the nasal application at all. It’s second nature. However, sometimes, it does get annoying. It gunks up in the nose and you have to take extra...

I have never heard this before. Is this your doctor telling you this?

I'm with you, brother. For reference, see my last 1000 posts!

Check out the lifting dermatologist on YouTube.

“I swear, honey - it tastes like cotton candy…”

I forgot to ask - is all being applied on the scrotum?

@FunkOdyssey, I was thinking about you recently, so this is good timing. Glad to hear it. Scroll up and you'll see my labs, which look nearly identical to yours. I felt pretty bad at those levels. I have since modified the protocol and currently also feel pretty good on cream. The reason I was...

I love it. I take it like i’m being nudged by a brother! Sorry to hear you’re dealing with mood issues. Jury is still out for me. I am battling fatigue. In the process of dropping dose to see if it gets better. After doing some reading, it looks like I got put on a high dose pretty damn quickly...

I actually have stuck with various protocols for extended periods of time. Just in the last 2 years, I’ve struggled. I am currently on cream. been on it pretty much for the last 3 to 4 weeks.

Wait - @Charliebizz, didn’t I specifically ask that you not jump on me?!? ;)

Getting to the root cause is critical. I definitely agree with you on that. I’ve taken to a lot of contemplative leaning teachings, which has been helpful.

Appreciate the thoughts. My bad - I wasn’t clear. I am tapering the SSRI, not TRT! The gut is and diet are definitely important!