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Question for @RobRoy about absorption: Do you think it is possible for absorption characteristics to change over time? I have been on a consistent dose of scrotal cream for about 5 weeks. The same dose in the past, applied the same way, made me feel crazy and my labs were all out of whack. This...

I use it. Very useful.

I think your use of the term “brain fog“ may not be completely in line with what most people are describing when they use that term. Sounds like you have a lack of focus and/or concentration? Do you think you could be experiencing anxiety?

Glad to hear it was working for you. In general, I thought it was a great mode of treatment because side effects were virtually nonexistent. But, I also found that it was hard to dose consistently, and it didn’t occur to me until I stopped using it, but I really did not like the stuffed up nose...

This program actually seems to work well and has a place for some. I started a similar program through Vytal Pharmacy. I got an email a while back saying that Sterling would assume my Rx moving forward. I am an oddball in that Xyosted tends to be the only injectable testosterone that I can...

How do you feel?

I think you are on to something. Cream has been a box of chocolates for me - on any given day, you never know what you are gonna get, brother!

About a month ago, I posted somewhere in this thread that I got labs pulled about 5 hours after applying cream. For some crazy reason, it took this long to finally get some of the results. For context, I had injected a total of 55mg within a week of getting the labs. The last injection was 10mg...

Excellent point. Diet is extremely important. I dropped to very low carb several years ago ("ancestral" type of diet as named by Josh Turknett, a migraine neurologist, but not carnivore) and noted a huge increase in energy and drop in headaches. That said, my carb intake has drifted up, but...

Agree with this, but wow. That would not be pleasant...

No arguments here. It’s fairly complex and really hard to know where to start, when to push it, when to back off, etc.

Well, at least you know who you are and what you are, which I think is good.

I get Natesto from a local doc at a local pharmacy. Empower does not have it, but if you want it, Defy, or any qualified physician, can prescribe it to whatever pharmacy you use. You should read up on it. If you want to try to stick to injections, there are lots of different types of carriers...

Natesto is easy, gives very quick results and does not cause any side effects besides the annoyance of putting up your nose. Jatenzo was OK, but I think I got some G.I. side effects that were unpleasant and I felt tired on it. Not sure if I gave it enough time, though. Injections suck for me...

Very well said, @Charliebizz.

Indeed, brother.

With all due respect, this is a dangerous approach to science.

I for sure considered this. Most recent TSH is normal. In past, rT3 was a bit elevated and my ratio was not ideal. Would consider checking again. Now for the grenade….. I took Accutane and finished a 6 month course shortly before the fatigue started…..

In short, turns out I already had it. I didn't realize until I looked closely at the bottle. It's from a local pharmacy. Longer story: I have tried it before in small quantities (10-15mg at a time), which is why I was hypothesizing (hoping) that perhaps there is some threshold below which...

Did you change your needle/syringe size? This stuff is pretty thick.

@FunkOdyssey, you may have answered this, but were you injecting this amount or similar amounts prior to getting the Hikma brand? Is everything else similar? One of the reasons I ask is based on my observation that I feel like crap with most injections except Xyosted. My theory has been that it...

I definitely agree. I seem to tolerate Xyosted fairly well, but it’s expensive and obviously you’re boxed in by the fixed dosing. Only explanation I can think of is the lack of excipients/preservatives.

Appreciate the feedback. I actually do understand how much these levels can vary throughout the day. I have a very specific and relatively new phenomenon that I’ve been experiencing for about six months. I have been extremely deliberate and have worked through a process of elimination to try to...

Dammit. I hadn’t thought this through, apparently. @RobRoy, in my situation assuming I want cream to be my primary TRT modality, but also need to raise my E2 levels (still a debatable concept), would you simply add testosterone injections? I’m still evaluating past labs and current labs, but...

What kind of doses are you doing EOD?

Anecdote: I posted recently about getting labs while feeling shitty on cream. Still waiting on some results, but so far, labs demonstrate modestly, elevated DHT (99) and moderately low estradiol. For the first time in my TRT journey, I am contemplating that some of my negative experiences could...

I think this concept is a slippery slope that we throw around here. While some of the technical observations may be correct that DHT is regulated at the cellular level and serum levels don’t matter, one can argue that this is a very common phenomenon, and none of the stuff we measure in the...

Awesome. I want the lizard, too!

Oh, and I forgot to follow up on my post above. I tried the MCT injections for a few days. Obviously, it's a very short time, but I noticed the same issues I did with other injections: headache and crappy feeling. So, I am inclined to say my issue is not the oil. That's not to say that some oils...

@FunkOdyssey, from what I understand, Hikma is the actual manufacturer, but it is sold under various brands. Which brand do you have?

Wow. This is great stuff. Please keep us informed. I think this stuff really matters (excipients and preservatives) to some that are sensitive.