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Feels great acutely in terms of increased drive and libido. I haven't been able to take it long term because high DHT somehow gives me gastritis, but I saw a trend towards mood and libido worsening as I stayed on it longer, similar to effects I've had with DHT derivatives.

I had more hair loss on higher dose test prop (25-30 mg daily), than on 20 mg prop with pure DHT added in top via gel which raised my DHT over 300 ng/dL. The pure DHT is a great way to experiment with this in a more controlled fashion.

It would vary with the tissue. No doubt higher serum DHT has CNS effects that are subjectively obvious; bone is another tissue directly affected by serum DHT in an animal model: https://www.sciencedirect.com/science/article/abs/pii/8756328296001354 The prostate is your prototypical...

The mechanism is conversion of testosterone to DHT by 5-alpha reductase within the scalp tissue. Some evidence to support the concept that serum DHT is not meaningful for hair loss compared to locally produced DHT: topical 5-alpha reductase inhibitors applied to the scalp are able to produce...

I'm pretty good. I've been doing somewhere around 20 mg test prop daily for quite awhile, with occasional experiments thrown in. I'm in the middle of quitting coffee for the 10th time so currently feeling garbage, but normally I feel pretty good on that dose of prop. I never did try the dht...

I know you ran a sort of TRT+ protocol for a long time, using a test enanthate base and smaller complimentary doses of deca and primo. It seems like you ran that for years if I'm not mistaken. How does your current deca base with a small dose of test prop compare to your old TRT+ protocol?

DHT in the scalp, not DHT in the serum - discussed further in this post: https://www.excelmale.com/threads/maximus-native-t-gel-vs-oral.31660/post-296255 You spiked your free T quite high by adding cream on top of your existing injection protocol.

You added cream on top of your injections - did you reduce your injection dose? I would suggest the increased free T was primarily responsible for your hair loss, not the DHT.

You don't want to run cream EOD - levels would be terrible on the second day. Forget about SHBG when the goal is increased free testosterone. It is a common misconception that SHBG is causing your free T to be lower than it would otherwise be. You increase free T by increasing your rate of...

First, oral testosterone produces supraphysiologic serum DHT levels just like topical TRT. However, elevated serum levels of DHT don't usually translate to increased hair loss like you might expect. In androgen-sensitive tissues like the skin, prostate, etc, the primary source of DHT continues...

After reviewing literature on the mental health and general health benefits of carnitine, creatine, taurine, CoQ10, B12, etc, one may be inclined to increase their consumption of these nutrients. You could create an elaborate supplement regimen with fistfuls of pills, or simply eat red meat.

I should also mention that this was not a trough test, but actually closer to a peak test, as I ran it five hours post injection.

I was a higher SHBG guy and have become a normal SHBG guy. I was up around 55-60 pre-TRT, and this dropped to around 30 with TRT in the 140-175 mg weekly range. I haven't seen any significant difference between enanthate and prop with regard to SHBG. It was about 38 ng/dL if I recall...

If you guys are already injecting daily, I think you might have better luck with propionate. I have a lower hematocrit with prop, fewer problems with E2, lower BP, better sleep. The result of all this is that I can comfortably tolerate much higher doses of prop. With cypionate, I too was...

You've heard it reported now. Anastrozole can be very effective in some (not all) cases of TRT-induced acne. I've experienced it personally and seen many many similar anecdotes. You'll find hundreds on Reddit.

They aren't responding to my email in a timely fashion either.

Estrogen bomb, between the strong phytoestrogen hops in an IPA and aromatase stimulation of the alcohol itself. This is one of the worst possible lifestyle habits to pair with high dose TRT.

I would guess that your levels of everything, T, DHT, and E2 are lower, certainly from the reduced/ more frequent hCG, possibly from the switch from IM to subq, and possibly due to both. Your E2 before was probably too high for good EQ, and now it is not. I would run your labs, then leave the...

What an inspiration! 93 years old, running 250 mg a week with good bloodwork for the sexual benefits. I'm not sure which I love more: the fact that you're doing it, or how much you triggered madman by posting about it. Rock on Bremster!

It's the estradiol setpoint that is most impactful here, and this usually doesn't differ for men with secondary hypogonadism. In my view, the only reason most men with secondary hypogonadism have it is because they are able to reach their estradiol setpoint with less testosterone, because they...

Yeah, I'm coming around to this, after observing some clear cognitive decline in myself with longer use of TRT. However, I'm skeptical that supplementing a couple things like preg or DHEA can counter the complete effects of HPTA shutdown and the 12+ disrupted hormones/neurosteroids.. I'm going...

From our own experience and what I've read from other women, it's usually progesterone that ruins everything and overshadows the energy, mood, and sexual benefits of estradiol and testosterone. Progesterone often makes them fatigued, apathetic, and kills their libido (similar to the effects in...

Knowing what I know now, before marriage, I would confirm that a woman was willing to do whatever was necessary in terms of HRT to maintain their sexual function through middle age and beyond. Otherwise, you have a good chance of spending the last half of your life in a dead bedroom situation...

1) Madman is correct on many things, but not the effects of ester. 2) Steroidplotter is very inaccurate / unrealistic. Use steroidplanner.com for more realistic modeling. 3) I guarantee there is no dosage of Cypionate taken E4D that will duplicate the effects of your ED propionate protocol...

That could be due to simply taking estradiol too low with the AI effect. If that's the case, you can supplement your way out of that with injectable estradiol. I'm really interested to see the outcomes of these protocols, because they will shed light on key questions, like what is the...

ChatGPT is correct - FSH increases testicle size independently from LH, and you will see greater ball gains with healthy levels of both LH and FSH. You're running on one leg with hCG.

If I were in this situation with the absurd E2 level after injecting a tiny dose of testosterone subq, the very first experiment I would run is to switch to shallow IM. I would use your same gauge needles, at least 1/2", and go straight into the delts, and then repeat labs in a week. There has...

They went big on claims, short on references. Progesterone makes.some sense in theory, and is harmless enough for all to try. Just don't be surprised if you are among the 97% that discontinue, because it either failed to improve anything or made things worse.

If you know anything about Empower, you know their fulfillment turnaround time is abysmal compared to other compounding pharmacies.

I made them a new logo that more accurately represents the Empower customer experience: