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You were evaluated with the appropriate estradiol test (resulting in a 27.8 value) but there is no reason for estrone to have been run, none at all. It gives your doctor no information that is actionable. Don’t pay for it again. The FSH indicates you are likely hypogonadal as a result of...

You don’t need to run LH and FSH - it’s too late. Those tests can not be completed once exogenous testosterone has been initiated since natural production has been shut down. They would have given valuable insight into whether you are dealing with primary or secondary hypogonadism (which would...

The pre-treatment tests to fully evaluate where things stand. Total and free testosterone LH and FSH SHBG Estradiol, Sensitive, LC,MS/MS CBC CMP Thyroid evaluation - ft3, ft4, rt3 Prolactin PSA DHT DHEA

Always test just prior to an injection - you want to capture your levels in the trough so you and your doctor can determine how well your protocol is sustaining itself over the course of the week - never “within 2-3 days of injections.” When were the results you posted obtained? SHBG is a...

Thank you for checking in. I’m glad to know that life is good.

I would note that, based on the reference range, you tested your estradiol with the incorrect (standard) test that is of no value for men. All men should test e2 with the sensitive, LC, MS/MS, lab test. Please be sure your doctor selects the correct test in the days ahead. This is important.

I'm lean and my injections tend to be shallow IM or subQ.

I’ve done the same thing, as part of my daily injection protocol, for nearly five years.

I invite @Shad0w to open a new thread to track his progress and solicit opinions on his efforts.

I drove to Erie, PA a number of times from Toronto and have also used Discountedlabs.com in Los Angeles, Atlanta, and Chicago. Walk in - hand them the lab order - confirm your identity - have the blood drawn.

They’ll be happy to works with you. I ask @Jesse-Defy to deal with any specific questions you might have offline.

Yes, they will. www.discountedlabs.com

Very good point. I dropped my total estradiol by 21 units four years ago when I moved from twice weekly to daily injections.

You could have saved money with www.discountedlabs.com.

Exactly what I thought. I find it’s a good idea to get a copy of lab results from the patient portal, as it is known here in Canada, or from the doctor. The chances of something going wrong when you’re playing TRT Sweepstakes is always a possibility. We have to be our own advocates.

Before the sensitive estradiol test was available in Canada I initially drove over the border to Buffalo and had blood drawn via Discountedlabs. It worked until someone at LabCorp caught the address of the ordering physician. Then I drove a bit further to Erie, PA. Later, flying for business, I...

If your estradiol was tested via any method other than the sensitive, LC, MS/MS, methodology, just exactly where your e2 sits is an open question since all other tests are unreliable when used to capture a man’s estradiol level. A cutoff of 50, assuming you’re in the United States, indicates...

I can’t say I have listened to this entire presentation, but I came across this when I was considering what my options were in the face of a rising PSA. It’s a balanced discussion.

And, if you make this adjustment, be patient. Make this one change, and give your system the required number of weeks for serum levels to adjust. It’s a step-by-step process.

The search function returned one reference to Dr. Mondell.

First of all, the important point, everyone here is glad to know you are stable and wish you a full recovery. Here are some studies as you asked for. Does Testosterone Increase the Chance for a Heart Attack? https://www.mayoclinicproceedings.org/article/S0025-6196(17)30824-8/fulltext TRT and...

No one can answer that question with certainty at this point. Serum levels are in flux, and that includes estradiol. In five or six weeks you’ll draw blood and look at the landscape; you will have the answer to your question then. If your doctor did not feel that anastrozole was necessary at...

All sorts of things begin sorting themselves out when exogenous testosterone is introduced. It will take a number of weeks for you to determine where things stand. Stay the course and be patient.

Yes - some “medical” professional has to write the order.

Of course it is “a long process” as he is likely making it up as he goes along.

In Quebec, a doctor’s order is required for lab work. Article 136 of Quebec’s “Regulation respecting the application of the Act respecting medical laboratories, organ and tissue conservation and the disposal of human bodies” any laboratory analysis must be requested by a medical professional...

I will support @madman when he emphasizes how important it is to maintain a stable - no change at all - protocol for the first weeks you are on an androgen replacement protocol. That same advice is true anytime you initiate any change as you seek to tune your efforts. Change...wait...analyze...

If you have it all, please post it, make sure you include the reference ranges!

Thank you for the kind words. They are much appreciated. As I referenced in an earlier post, I find the only way to deal with the anxiety that follows in the wake of concerning medical news is to become as knowledgeable as I can about the issues I face. I read any and everything I can and make...

A prostate biopsy is not anathema for me, but in my case - and I only speak for myself - I came to the conclusion that it wasn’t warranted. I spoke to a classmate, from undergraduate days, who is the head of the urology section at a teaching hospital in Atlanta, a friend, who said that in his...

How old are you? How long has this self-driven experiment been going on? Have you discussed any of this with a doctor? You have to get lab work done. You can order it yourself if you live in the United States, www.discountedlabs.com, or your doctor can order it for you. At a minimum: total and...