Recent content by Soalian

where do you stand nowadays on the LH issue on TRT, regarding the suppression of brain LH receptor activation, possibly leading to missing out on putative benefits from neurological effects from having brain LH (or LHR analogs such as HCG) ? It's still unclear to me whether or not brain LHR...

so I've been leaving a newly reconstituted HCG vial out at room temp for about 48 hours, should it still be g2g or not ?

@Cataceous so I'm one week into the Kisspeptin-10 250mcg daily (125cmg BID), so far nothing to report as of yet. I'm expecting very mild results, if anything noticeable at all.

Also @Cataceous , I've been on a test propionate regimen for about two years; I often inject ED or EOD. However, at times I've been injecting relatively low amounts, and/or skipping days or even a week. Given that test prop half-life is quite short, I wonder whether or not the negative...

Thank you, gnrh might also exert beneficial indirect effets on cognition as well: Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus

I know, I've been unsuccessfully looking for kisspeptin-54 before. had my first 200mcg kisspeptin injection this morning, how long do you take it might take to reap the subjective mental benefits of increased gnrh signaling ? (if any, whatever I will be able to notie in changes might be placebo).

Thank you for the link; my plan is to start a trial of kisspeptin-10 for backfilling the gnrh pathways (despite being on exogenous test, don't know how it will play out in practice, if I'll still be able to get the gnrh cascade activated or not). What do you think of using kisspeptin to tha...

Are you on exogenous test right now? Do you notice subjective changes in cognition from backfilling the gnrh and LH pathways through using gonadorelin and enclomiphene? I'm still torn on the benefits of adding HCG low-dose, due to the purported benefits of HCG on brain health through LH...

he question I also ponder about Kisspeptin and exogenous test, is at what level do androgens exert negative feedback on hypothalamus gnrh secretion; if it occurs right at the level of Kisspeptin signaling, then administering exogenous kisspeptin would still lead to gnrh being secreted in the...

In the case you have "normal" T levels naturally (well-functioning HPTA) but want to get more intratesticular testosterone production through higher LH synthesis in the pituitary from using enclomiphene in order to block the pituitary estrogen => LH negative feedback, you'll still be running...