Recent content by PhantomFear
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Arimidex - Pain Caused by Crashing E2 or Another Reason?
I appreciate your points, and I understand the limitations of those studies. I wasn't trying to claim that arimidex is dropping guys progesterone levels in half. I was suggesting that the side effect's associated with low doses - which are attributed to a reduction in estrogen, despite serum...- PhantomFear
- Post #22
- Forum: Testosterone Side Effect Management
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Arimidex - Pain Caused by Crashing E2 or Another Reason?
Anecdotally, I always got bone and joint pain when taking an ai. I'm currently off TRT right now and my estradiol is rather low, yet I have zero joint pain. Here are what my last set of bloods looked like: Testosterone: 18.2 nmol/L (500 ng/dL) (Range: 8.6 - 29 nmol/L) Estradiol: 55 pmol/L...- PhantomFear
- Post #20
- Forum: Testosterone Side Effect Management
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Arimidex - Pain Caused by Crashing E2 or Another Reason?
First generation ai's do cause more supression of upstream hormone production, mainly because they inhibit the conversion of cholesterol -> preg, and thus the entire steroid hormone cascade. Third generation ai's don't have this effect, but they do seem to effect progesterone significantly...- PhantomFear
- Post #19
- Forum: Testosterone Side Effect Management
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Arimidex - Pain Caused by Crashing E2 or Another Reason?
Most people don't understand that AI's aren't selective to solely aromatase. The enzymes in the steroid hormone cascade all belong to the same family. As a result, any substance that inhibits one will have an effect on another, albeit to a lesser degree. You can see this in the hormones...- PhantomFear
- Post #17
- Forum: Testosterone Side Effect Management
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Water Retention and Rapid Weight Gain Caused by Testosterone
It's caused by a poor progesterone:estrogen ratio. This isn't something that can be assessed using serum estradiol, as estradiol is not an endocrine, but a paracrine hormone. This means that is is produced and used in it's tissue of origin, meaning serum values are largely useless. Jefcoate...- PhantomFear
- Post #75
- Forum: Testosterone Side Effect Management
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My daughter has PCO and high DHEAS and testosterone . Advise please
What do her thyroid labs look like? Progesterone, Cortisol, Estradiol, Estrone Sulfate and Cholesterol would be helpful, too. I guarantee she has a thyroid issue, as is the case in all women with PCOS. This often goes unnoticed because the problem isn't always with the absolute amount of...- PhantomFear
- Post #2
- Forum: HRT in Women
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HPTA Recovery Log to Re Start Testosterone Production
I think it's due to my digestive issues, which I believe are a product of hypothyroidism and low adrenal function. I'll be retesting next week.- PhantomFear
- Post #11
- Forum: Testosterone Side Effect Management
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HPTA Recovery Log to Re Start Testosterone Production
Not sure why this post was renamed to HPTA recovery log. The point of this log is actually the exact opposite: to document my progress restarting TRT and fixing adrenals.- PhantomFear
- Post #10
- Forum: Testosterone Side Effect Management
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HPTA Recovery Log to Re Start Testosterone Production
First thing in the morning usually.- PhantomFear
- Post #8
- Forum: Testosterone Side Effect Management
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HPTA Recovery Log to Re Start Testosterone Production
I agree, it's vastly ineffective for the majority of people. it was never the long term plan, I just wanted to see if it'd improve my poor adrenal function since various studies show LH is important for adrenal steroidogenesis. Unfortunately it had the opposite effect.- PhantomFear
- Post #7
- Forum: Testosterone Side Effect Management
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Help me create a Hydrocortisone treatment
Do you think Adrenal Cortex Extract could achieve the same or similar? Interesting you mention Dr. Mariano, i see him mentioned everywhere yet I can't find any content from him directly online. Does he have any resources you could point me towards? I already know the same would happen to me if...- PhantomFear
- Post #12
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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Is there any reason someone would NEED hcg on a trt program?
Do you have a source for this? I see it claimed a lot, especially by stop the thyroid madness, yet I've never seen and cannot find a paper demonstrating it. Not suggesting it isn't true - just genuinely curious.- PhantomFear
- Post #28
- Forum: Testosterone Basics & Questions
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Help me create a Hydrocortisone treatment
Have you found your ability to tolerate thyroid increase with adrenal support via HC supplementation? When you tried T3 in the past, what happened? Anxiety, palpitations, nervousness etc?- PhantomFear
- Post #10
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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HPTA Recovery Log to Re Start Testosterone Production
After a week of ~5mg transdermal progesterone I've had to stop due to vascular issues. In the past whenever I've taken pregnenolone it's always caused my veins to swell, bulge and expand, permanently changing their appearance even after discontinuation - seems to be the start of varicose veins...- PhantomFear
- Post #2
- Forum: Testosterone Side Effect Management
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HPTA Recovery Log to Re Start Testosterone Production
Hello everyone. Following my failed attempt at restarting my natural testosterone production, I'm back on HRT in the form of 500iu HCG 3x p/w. ---------------------------------------------------------------------------------- Current issues: Always cold, especially extremities Absent Libido...- PhantomFear
- Thread
- anxiety cortisol dhea hcg hypothyroidism pregnenolone progesterone thyroid trt
- Replies: 10
- Forum: Testosterone Side Effect Management
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