a small daily dose is absolutely strongest than a single dose:
with 0,25mg only once week i had my estradiol from 68.5 to 58.5 with TT@10,9 ng/ml.
Probably if you use your microdose in a single dose you could have 10 points more of e2.
When i started trt @ 200 mg weekly, my TT was 23ng ml and...