Recent content by JustPanicNoDisco

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  1. J

    Persistent Low E2 symptoms lasting long after crash- Possible Solution or a little relief.

    Can you link the original Reddit thread where you pulled that PDF from? There are some interesting ideas, but I don't know how much weight it holds. I would like to question the writer a bit.
  2. J

    Persistent Low E2 symptoms lasting long after crash- Possible Solution or a little relief.

    Can you link the original Reddit thread where you found that PDF? Thanks
  3. J

    Estrogen valerate injections for crashed e2 symptoms

    Well, it's not low in serum, and it's not a standard treatment option for men -- at all. Hell, even TRT is very conservatively prescribed unless you go to a clinic. Good luck explaining a "receptor" problem to a doctor who practices medicine from a playbook. I doubt they're going to want to...
  4. J

    Permanent Damage from Estradiol Crash

    I'm confused. I remember in the original knockout/desensitization thread, you were posting about how you were getting off TRT to attempt a natural recovery -- something you seem to be championing here. Then... you say you are on 800 mg of TRT? I'm confused. Do you mind providing a more...
  5. J

    Which "part" of the HPTA is the hardest to "turn on" during PCT?

    For anyone else curious: Madman states: "Even without the use of a PCT, the natural production of LH will kick in fairly quickly but natural endogenous production of testosterone can take much longer as the critical aspect of the recovery process is the responsiveness of the Leydig cells in...
  6. J

    Which "part" of the HPTA is the hardest to "turn on" during PCT?

    I am getting off testosterone after two years (if you want back story, you can read my previous posts, and I'm unable to perform any conventional PCT as I cannot tolerate SERMs. I have, however, been entertaining the idea of using GnRH or hCG as a way to "prime" the body before coming off TRT...
  7. J

    Pituitary restart while on TRT: promising initial results with GnRH plus enclomiphene

    The literature body on people who have experienced shutdown for a prolonged period (however, some of this is using GnRH analogues, as in the case of prostate cancer research). It does seem most people, anecdotally, recover more quickly than 9-12 months, but often these people were just cycling...
  8. J

    Pituitary restart while on TRT: promising initial results with GnRH plus enclomiphene

    I appreciate the thoughtful response. Nine to twelve months to get to a baseline level of HPTA function just sounds absolutely brutal, but perhaps it's the way to go in my case, where so many systems are completely out of whack. Maybe throwing it into a tailspin and letting it re-calibrate...
  9. J

    Pituitary restart while on TRT: promising initial results with GnRH plus enclomiphene

    By the way, is there ANY literature suggesting that GnRH/gonadorelin can be used as a substitute for hCG with respect to maintaining testicular function (while on TRT, ofc)? Maybe @readalot would know? I know a lot of clinics chose to switch over, but I can't find any of the clinics citing...
  10. J

    Pituitary restart while on TRT: promising initial results with GnRH plus enclomiphene

    Great stuff, @Cataceous I'd like to hear your opinion regarding using GnRH alone as a restart tool -- a potential application you referenced in your initial post. I've finally decided to get off TRT. I started exogenous T to see if it could help with symptoms of PSSD (post-SSRI...disaster)...
  11. J

    SERM "PCT" Alternatives

    Fair points. I read through your TRT protocol and the theory behind it. It was definitely interesting. If I recall correctly, you mentioned synthetic GnRH potentially being used as a PCT tool after long-term TRT. Do you see gonadorelin as being a viable PCT alternative in isolation? It is my...
  12. J

    SERM "PCT" Alternatives

    @BigTex The publication you sent me showed that a single dose 100 ug dose of trip caused a HUGE rise in LH, peaking at about 40 mIU/mL within 30 minutes, and then slowly falling back down. I've heard people mention the risk of irreversibly damaging the HPTA with tript, and giving the dosing...
  13. J

    SERM "PCT" Alternatives

    I'm going to read more literature before attempting it, and hopefully even get a script from the doc under whom I have been using TRT. Thanks for the link.
  14. J

    SERM "PCT" Alternatives

    @Dicky And for anyone else curious, I have been running 22 mg EOD for several months and feel like shit. These are my blood results I recently received from Quest: DHT: 72 [12-65] -H E2, sensitive: 32 [ < 29 ] TT: 856 [250-1100 ng/dL] (lol did they finally raise the range) FT: 135 [35-155...
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