Recent content by Jim Marlowe

  1. J

    Kyzatrex - sudden emptiness feeling in head

    If DHT isn't tested, impossible to say. But I haven't heard that low estrogen (without an ai) causes "spaciness." I've heard the exact opposite: higher DHT improves thinking. That's what Hans Amato talks about.
  2. J

    Kyzatrex - sudden emptiness feeling in head

    Right. My suspicion is that they are comparatively low. If you were "locked in," I would guess higher DHT (relative to just T levels). "Spaciness" I wonder is relatively low DHT. Just speculation.
  3. J

    Kyzatrex - sudden emptiness feeling in head

    I'd be curious to know what DHT levels are at peak "spaciness."
  4. J

    Should I continue trt or not?

    From Georgi Dinkov: https://haidut.me/?p=2747
  5. J

    Anxiety from Kyzatrex?

    If you're feeling anxiety, it could be the result of the low or slow MAO-A gene, which can result in an imbalance of serotonin to dopamine. Basically serotonin is too high. If that is a factor then the solution could actually be to use whatever exogenous T you are using in a MORE in pulsatile...
  6. J

    Bioenergetics - Low TSH, low estradiol and high testosterone as indicative of suppressed thyroid function with high "tissue-bound" estrogen.

    Ray Peat on why "normal" thyroid function is misleading based the arbitrary determination that only five percent of the population was hypothyroid.
  7. J

    Bioenergetics - Low TSH, low estradiol and high testosterone as indicative of suppressed thyroid function with high "tissue-bound" estrogen.

    You wish it was lower as a result of cardiac fitness or lower because you subscribe to the rate-of-living theory?
  8. J

    Bioenergetics - Low TSH, low estradiol and high testosterone as indicative of suppressed thyroid function with high "tissue-bound" estrogen.

    It broad terms, it is suboptimal energy production from various causes including in large part consumption of PUFA. Burning glucose primarily (not entirely) through oxidative phosphorylation is the most efficient method (i.e. produces the most electrons for ATP). Bioenergetics rejects the rate...
  9. J

    Bioenergetics - Low TSH, low estradiol and high testosterone as indicative of suppressed thyroid function with high "tissue-bound" estrogen.

    Sure, that's what conventional wisdom would say. What Danny is saying is that the combination is indicative of hypothyroidism. From Roddy: "Prolonged cortisol excess and adrenaline can lower TSH" — Ray Peat "Aging, infection, trauma, prolonged cortisol excess, somatostatin, dopamine or...
  10. J

    Bioenergetics - Low TSH, low estradiol and high testosterone as indicative of suppressed thyroid function with high "tissue-bound" estrogen.

    Here's a post on X.com by Danny Roddy discussing the bioenergetic interpretation of high cholesterol, low TSH, low blood estrogen with high testosterone, and high SHBG.
  11. J

    My CAC calcium score is high- Should I take vitamin K?

    I would look into increasing magnesium and potassium consumption. Magnesium by way of drinking magnesium bicarbonate following Dr. William Davis's protocol. If you search his podcast and articles, you'll find his explanation on how he treated patients with magnesium deficiency. Also look into...
  12. J

    Everything Tesamorelin

    Have you changed the way you eat in light of the Tesamorelin? The conventional advice is to take it at least 90 minutes away from food. If you were used to eating any carbs before bed, it is possible that it is not the Tesamorelin itself, but the fasted state. You might see what happens if...
  13. J

    Injectable Progesterone SC may not be the best route of administration

    No. I have used Magnoil, which is magnesium (either L-pidolate or sulfate) and DMSO. It works great. However, I understand in recent years there have been reassessments about the use of DMSO in compounds. I know some people experience skin irritation, but I've never had that happen. I am not...
  14. J

    Injectable Progesterone SC may not be the best route of administration

    I'm not going to keep doing this, but here is Georgi Dinkov (timestamped) discussing his self-funded research regarding pro-metabolic treatment of cancer in mice. Again, from the "bioenergetic" perspective, Georgi talks about lipolysis in cancer metabolism, the similarity between Type 1...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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