Recent content by Jim Marlowe

If DHT isn't tested, impossible to say. But I haven't heard that low estrogen (without an ai) causes "spaciness." I've heard the exact opposite: higher DHT improves thinking. That's what Hans Amato talks about.

Right. My suspicion is that they are comparatively low. If you were "locked in," I would guess higher DHT (relative to just T levels). "Spaciness" I wonder is relatively low DHT. Just speculation.

I'd be curious to know what DHT levels are at peak "spaciness."

From Georgi Dinkov: https://haidut.me/?p=2747

If you're feeling anxiety, it could be the result of the low or slow MAO-A gene, which can result in an imbalance of serotonin to dopamine. Basically serotonin is too high. If that is a factor then the solution could actually be to use whatever exogenous T you are using in a MORE in pulsatile...

Ray Peat on why "normal" thyroid function is misleading based the arbitrary determination that only five percent of the population was hypothyroid.

You wish it was lower as a result of cardiac fitness or lower because you subscribe to the rate-of-living theory?

It broad terms, it is suboptimal energy production from various causes including in large part consumption of PUFA. Burning glucose primarily (not entirely) through oxidative phosphorylation is the most efficient method (i.e. produces the most electrons for ATP). Bioenergetics rejects the rate...

Sure, that's what conventional wisdom would say. What Danny is saying is that the combination is indicative of hypothyroidism. From Roddy: "Prolonged cortisol excess and adrenaline can lower TSH" — Ray Peat "Aging, infection, trauma, prolonged cortisol excess, somatostatin, dopamine or...

Here's a post on X.com by Danny Roddy discussing the bioenergetic interpretation of high cholesterol, low TSH, low blood estrogen with high testosterone, and high SHBG.

I would look into increasing magnesium and potassium consumption. Magnesium by way of drinking magnesium bicarbonate following Dr. William Davis's protocol. If you search his podcast and articles, you'll find his explanation on how he treated patients with magnesium deficiency. Also look into...

Have you changed the way you eat in light of the Tesamorelin? The conventional advice is to take it at least 90 minutes away from food. If you were used to eating any carbs before bed, it is possible that it is not the Tesamorelin itself, but the fasted state. You might see what happens if...

No. I have used Magnoil, which is magnesium (either L-pidolate or sulfate) and DMSO. It works great. However, I understand in recent years there have been reassessments about the use of DMSO in compounds. I know some people experience skin irritation, but I've never had that happen. I am not...

I'm not going to keep doing this, but here is Georgi Dinkov (timestamped) discussing his self-funded research regarding pro-metabolic treatment of cancer in mice. Again, from the "bioenergetic" perspective, Georgi talks about lipolysis in cancer metabolism, the similarity between Type 1...