Recent content by FDV70

That's right, not as much as phlebotomy.

So first we need to understand where serum ferritin originates. Ferritin comes in different types (isoforms) (adapted from my site): H-ferritin (Heavy chain, FTH1). “Heavy” but stores less iron. Typically stores 500–1,500 iron atoms. Heavy has a less stable ferrihydrite core which allows for...

hCG is just an LH stand-in. There is no mechanism for it to reduce hepcidin either directly or indirectly. "And your second: Can you clarify -- my understanding is that the high hematocrit on TRT is due to most iron being utilized for red blood cell production in lieu of being bound via...

It's either something I wrote or something of mine someone added to Here is the whole protocol https://vorck.com/erythrocytosis.html Here is the trial version of Protocol 2: https://vorck.com/protocol-revision-apr2025.html

Thanks so much FunkOdyssey! 8 units was good for 2 hours. Much appreciated. [The only curious thing was that it took 10 minutes to 'hit' even with massaging it around, but no matter.]

I finally got bimix that works, I was getting a premix product and not a lyophilized product. It was probably inert from lack of refrigeration. I did 4 units of a 30mg Papaverine, 1mg Phentolamine per 1ml product. I got a chub for about 40 minutes. My "antidote" vial is on backorder so I want...

All of you, I want to thank you on this -- I ordered a lyophilized vial and THAT worked. It is clear to me that the bimix I was using before was probably dead on arrival from being a premixed product and not being refrigerated. Also, I used a half inch needle and put it to full depth and it...

I have written letters to their medical director and CEO on two different occasions. By their public posts and SEC Form 10-K it is clear they think their product is only for PV and hemochromatosis. Their tweets show they don't realize there are ANY other issues from low hepcidin. It makes me...

https://vorck.com/erythrocytosis.html The study is from 2014, the same year erythroferrone was discovered, which is the missing link here and the reason the connection between RBCs and hepcidin is vague in the link. Erythroferrone is produced by erythroblasts (immature RBCs) in response to...

In ******** groups. TRT Community and Nelson's TRT FB group, Testosterone Replacement Therapy Discussion. Guys at 56 all the time, guys at 60 a few a month freaking out.

Wow that's fucked up. I am on ChatGPT 4.o and typed: "read this Fixing High Hemoglobin or Hematocrit and Low Ferritin While on TRT then I want to ask questions" "Tell me what causes low ferritin while on TRT and how to fix it." It gave completely wrong information, as it did to you. I then...

Remember that you need to train your AI model first. AI has NO IDEA that we cannot build ferritin on TRT, never mind why. It's why AI says dumb shit like take vitamin C. Consume heme iron (JFC NO THAT WILL NOT HELP, CLAUDE!!!!!). Everything it tells you to do will drive hemoglobin higher...

The signal to noise ratio pollutes the whole discussion. I see SO MANY people comparing TRT to living at elevation. Except people at elevation STOP going up, because the mechanism of their erythrocytosis if activation of HIF1 and HIF2 which increase EPO but in TRT, Testosterone has a direct...

IP6 and curcumin both chelate iron, so those will lower ferritin. I wonder if he had inflammation "fighting" his lowering. Lactoferrin will transport iron anywhere in parallel with transferrin, so that is neither here nor there. It's just more carrying capacity. Zinc isn't involved in the...

If you can build ferritin past 30, you can do my protocol generally. What concerns me is that you have a saturation of 94%. That's fasting I presume. I gotta ask. C282Y is a disorder of the pathway we use to build the ferritin, the BMP/SMAD pathway (there are two pathways, IL-6 and BMP/SMAD)...