Recent content by edward

Morning erections that go away rapidly after that first urination are actually pseudoerections.

The most important things to do in order to minimize the risk of fibrosis (scar tissue formation) from penile injection therapy are: 1) Use a very fine or small gauge needle (30 or 31G) to reduce tissue trauma. 2) Stretch the penis out while grasping the glans before the injection and while...

I have treated thousands of patients with intracavernous pharmacotherapy (trimix or quadmix), and in some cases the patient built up a tolerance over time requiring increasingly higher doses or more potent formulas. Assuming your technique is good and the compounding pharmacy is formulating the...

High E2 increases SHBG which in turn reduces free T. That is the relationship here.

Doxazosin (Cardura) does not help ED symptoms. Many BP meds dilate blood vessels and some can cause ED symptoms. If you have generalized anxiety, which I believe you mentioned, that for sure can cause ED just like depression can. Cialis 5mg daily is marketed for ED but IMO it frequently doesn’t...

The ratio of zinc to copper should be ~10:1. If you’re taking a MVI, check the amount of copper in it. For zinc 40mg, the intake of copper should be ~4mg. If the MVI has less copper than 4mg, then it should be supplemented accordingly. It’s my understanding that zinc is only effective in this...

Thanks for your comment. Penile injection therapy must be individualized as to the potency and dose of the formula due to differences in severity of ED and as to the needle length due to differences in penile shaft thickness. I worked part time for a multinational company which exclusively...

I made an inadvertent error regarding my recommendation for the length of the needle. I meant to write 5/16” which is 8 mm. One consideration is the thickness of one’s penile shaft. If a patient is on the thicker side then a 1/2” needle should be fine. If the penile shaft is less thick or...

I as a physician used to prescribe trimix. I recommend the B-D 1 ml or 100 unit syringe with a 31 gauge, 3/16” length (labeled ultrashort) needle. You should inject straight in and all the way at the 10:00 or 2:00 position near the base of the penis. The penis should be pulled or stretched out...

Thanks again. I’m on SQ T-cyp which takes longer to be absorbed than IM so I suspect that the peak blood level takes somewhat longer to achieve. I’ll likely continue taking the AI 24 hrs. after my shot and see what the labs show; then do a new post.

I think that SQ T-cyp takes longer to peak than IM. What type of injection do you use? Also, do you take anastrazole and if so when relative to the T shot?

I saw a post by you I believe Vince advocating the use of an AI (anastrazole) 24 hours after a T-cyp injecition so that the AI and T-cyp would peak at the same time. It’s my understanding that the T-max or peak blood level for anastrazole is at ~1 hr. with a half-life of ~50 hours and that T-cyp...