Recent content by billsman

Can you elaborate on "Top it off that you will not be hammering the s**t out of your CNS or DOPAMINE 24/7!?" How does test affect dopamine?

I will be starting Kyzatrex soon, as I've had high crit due to injection. One wonders if there's any real difference in the three other than dose.

I'm beginning to wonder whether a hepcidin-mimetic would be of any help. As I understand it, increased hepcidin results in lower ferroportin levels, which decrease iron absorption from the gut. This, then, reduces the production of red blood cells. But if iron absorption is reduced, how would...

Thanks for responding. It's been a long-standing issue and hydration doesn't move the reading much. High crit started when I moved to injectable test. My low ferratin and low iron have resulted in bad fatigue.

My reading is that the testosterone pills like Jatenzo are least likely to elevate crit. My assumption is that this is due to its bid dosing, resulting in less of a spike. So why are so few guys taking Jatenzo? I tried it when it first came out, but was disappointed -- but perhaps I didn't...

Can you clarify what you mean by H&H?

Man, I was prescribed 10,000 IU x 5 ml water -- 1.3 cc dose 3x per week for 10 years. Yeah, I had gyno after that mess.

I'm afraid you're correct about rusfertide. However, my hope is that there will be competitors in the future. I tried Jatenzo in the past and it didn't produce good levels for me. I'm not looking for supra-levels -- just 500s. I've been on TRT for over 25 years, but I've only had high...

So I am at a point where my iron and ferritin are chronically low. I take xyotsed 100 mg per week. I do TP every 2 months. Something has to give. My question: other than gels, are there other TRT that do not produce erythrocytosis?

You're correct. Thanks for pointing that out.

Some may be interested to know that the FDA approved rusfertide as a breakthrough treatment for PV. Not sure that's going to help folks like me with chronically low ferritin. From what I can find out thus far, the out-of-pocket cost would be $120k per year. But at least there is a...

Your first point: Are you saying that E2 elevations via hCG are produced in the testes? And your second: Can you clarify -- my understanding is that the high hematocrit on TRT is due to most iron being utilized for red blood cell production in lieu of being bound via ferritin. Thx for...

Do we understand why hCG does not lower ferritin via hepcidin?

Anyone know if rusfertide is coming out soon? I know it is in phase III. That would be a game changer.

I appreciate the response. I was on hCG for 10 years to have kids. At the end, I had irritability and high estradiol. I know the latter can be controlled with an AI. I am considering returning to hCG as my ferritin levels have been very low for many years. I have been on TRT for 28 years...