Recent content by billsman
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Is Rusfertide FDA Approved to Manage Erythrocytosis in Polycythemia Vera?
I'm beginning to wonder whether a hepcidin-mimetic would be of any help. As I understand it, increased hepcidin results in lower ferroportin levels, which decrease iron absorption from the gut. This, then, reduces the production of red blood cells. But if iron absorption is reduced, how would...- billsman
- Post #11
- Forum: Testosterone Side Effect Management
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Warning for Men on TRT: Low Ferritin is Bad
Thanks for responding. It's been a long-standing issue and hydration doesn't move the reading much. High crit started when I moved to injectable test. My low ferratin and low iron have resulted in bad fatigue.- billsman
- Post #228
- Forum: Testosterone Side Effect Management
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Warning for Men on TRT: Low Ferritin is Bad
My reading is that the testosterone pills like Jatenzo are least likely to elevate crit. My assumption is that this is due to its bid dosing, resulting in less of a spike. So why are so few guys taking Jatenzo? I tried it when it first came out, but was disappointed -- but perhaps I didn't...- billsman
- Post #226
- Forum: Testosterone Side Effect Management
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Warning for Men on TRT: Low Ferritin is Bad
Can you clarify what you mean by H&H?- billsman
- Post #224
- Forum: Testosterone Side Effect Management
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HCG Reconstitution Calculator- HCG Dosage Calculator
Man, I was prescribed 10,000 IU x 5 ml water -- 1.3 cc dose 3x per week for 10 years. Yeah, I had gyno after that mess.- billsman
- Post #12
- Forum: "How to" Guides
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Is Rusfertide FDA Approved to Manage Erythrocytosis in Polycythemia Vera?
I'm afraid you're correct about rusfertide. However, my hope is that there will be competitors in the future. I tried Jatenzo in the past and it didn't produce good levels for me. I'm not looking for supra-levels -- just 500s. I've been on TRT for over 25 years, but I've only had high...- billsman
- Post #9
- Forum: Testosterone Side Effect Management
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Is Rusfertide FDA Approved to Manage Erythrocytosis in Polycythemia Vera?
So I am at a point where my iron and ferritin are chronically low. I take xyotsed 100 mg per week. I do TP every 2 months. Something has to give. My question: other than gels, are there other TRT that do not produce erythrocytosis?- billsman
- Post #6
- Forum: Testosterone Side Effect Management
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Is Rusfertide FDA Approved to Manage Erythrocytosis in Polycythemia Vera?
You're correct. Thanks for pointing that out.- billsman
- Post #3
- Forum: Testosterone Side Effect Management
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Is Rusfertide FDA Approved to Manage Erythrocytosis in Polycythemia Vera?
Some may be interested to know that the FDA approved rusfertide as a breakthrough treatment for PV. Not sure that's going to help folks like me with chronically low ferritin. From what I can find out thus far, the out-of-pocket cost would be $120k per year. But at least there is a...- billsman
- Thread
- ferratin rusfertide
- Replies: 10
- Forum: Testosterone Side Effect Management
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Warning for Men on TRT: Low Ferritin is Bad
Your first point: Are you saying that E2 elevations via hCG are produced in the testes? And your second: Can you clarify -- my understanding is that the high hematocrit on TRT is due to most iron being utilized for red blood cell production in lieu of being bound via ferritin. Thx for...- billsman
- Post #216
- Forum: Testosterone Side Effect Management
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Warning for Men on TRT: Low Ferritin is Bad
Do we understand why hCG does not lower ferritin via hepcidin?- billsman
- Post #214
- Forum: Testosterone Side Effect Management
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Warning for Men on TRT: Low Ferritin is Bad
Anyone know if rusfertide is coming out soon? I know it is in phase III. That would be a game changer.- billsman
- Post #212
- Forum: Testosterone Side Effect Management
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Warning for Men on TRT: Low Ferritin is Bad
I appreciate the response. I was on hCG for 10 years to have kids. At the end, I had irritability and high estradiol. I know the latter can be controlled with an AI. I am considering returning to hCG as my ferritin levels have been very low for many years. I have been on TRT for 28 years...- billsman
- Post #210
- Forum: Testosterone Side Effect Management
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Warning for Men on TRT: Low Ferritin is Bad
Sorry, maybe I missed it, but could you point me to your resource on TRT and erythroferrone flooding? I've had ferritin levels below 12 for three years and need to understand the process better.- billsman
- Post #208
- Forum: Testosterone Side Effect Management
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Chronically low ferratin levels
I have been on TRT for 28 years. As with most people who are long-term folks, I've had issues with high red blood cell production for years. I use therapeutic phlebotomies every two months to keep my crit in line. But my ferritin has been low for many years. I'm around 15 and just tired all...- billsman
- Thread
- ferratin
- Replies: 1
- Forum: Testosterone Side Effect Management
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