Many signs of aging, such as sexual dysfunction, visceral obesity, impaired bone and muscle strength, bear a close resemblance to features of hypogonadism in younger men. The statistical decline of serum testosterone in aging men is solidly documented. ...
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*When Prof. Alex Vermeulen from Gent/Belgium in the 1970s started his pioneering work on the decline of testosterone levels in aging men, his work seemed to most professionals only of theoretical interest (for review:1). But further studies have substantiated that, with age, a significant percentage of men over the age of 60 years have serum testosterone levels below the lower limits of normal for young adult men (aged 20–30 years) 2, 3. Now, 30–40 years later, the pathophysiological implications of this decline, sometimes amounting to outright testosterone deficiency, have become clearer
Abstract. The free and nonspecifically bound plasma hormone levels generally reflect the clinical situation more accurately than total plasma hormone levels. He
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